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Measuring Hemoglobin Levels in the Optic Nerve Head for Glaucoma Management

  • Manuel Gonzalez-de-la-Rosa
  • Marta Gonzalez-Hernandez
  • Carmen Mendez-Hernandez
  • Elena Garcia-Martin
  • Francisco Fumero-Bautista
  • Silvia Alayon
  • Jose Sigut

Abstract

Description of the method Laguna ONhE that measures the amount of hemoglobin at the optic nerve head from color fundus pictures. It shows the basis of the method and its application to glaucoma and other pathologies that affect the optic nerve.

The amount of hemoglobin is one of the most important indexes in optic nerve perfusion. This chapter gives a thorough explanation of the method, as well as its graphic and numeric results.

Keywords

Optic Neuritis Optic Nerve Head Central Retinal Artery Lamina Cribrosa Glaucomatous Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

  1. 1.
    Gonzalez de la Rosa M, Gonzalez-Hernandez M, Sigut J et al (2013) Measuring hemoglobin levels in the optic nerve head: comparisons with other structural and functional parameters of glaucoma. Invest Ophthalmol Vis Sci 54(1):482–489CrossRefPubMedGoogle Scholar
  2. 2.
    Denniss J (2013) Estimation of hemoglobin levels in the optic nerve head for glaucoma management. Invest Ophthalmol Vis Sci 54(2):1515CrossRefPubMedGoogle Scholar
  3. 3.
    Gonzalez de la Rosa M, Gonzalez-Hernandez M, Sigut J et al (2013) Author response: estimation of hemoglobin levels in the optic nerve head for glaucoma management. Invest Ophthalmol Vis Sci 54(3):2011–2012CrossRefPubMedGoogle Scholar
  4. 4.
    Bambo MP, Garcia-Martin E, Perez-Olivan S et al (2013) Diagnostic ability of a new method for measuring haemoglobin levels in the optic nerve head in multiple sclerosis patients. Br J Ophthalmol 97(12):1543–1548CrossRefPubMedGoogle Scholar
  5. 5.
    Bambo M, Garcia-Martin E, Perez-Olivan S et al (2014) Detecting optic atrophy in multiple sclerosis patients using new colorimetric analysis software: from idea to application. Semin Ophthalmol:1–4. doi: 10.3109/08820538.2014.962171
  6. 6.
    Mendez-Hernandez C, Garcia-Feijoo J, Arribas-Pardo P et al (2014) Reproducibility of optic nerve head hemoglobin measures. J Glaucoma. 27 Oct 2014 [Epub ahead of print]. PMID: 25350818Google Scholar
  7. 7.
    Bambo MP, Garcia-Martin E, Satue M et al (2014) Measuring hemoglobin levels in the optic disc of Parkinson’s disease patients using new colorimetric analysis software. Parkinsons Dis 2014:946540PubMedCentralPubMedGoogle Scholar
  8. 8.
    Pena-Betancor C, Gonzalez-Hernandez M, Fumero-Batista F et al (2015) Estimation of the relative amount of hemoglobin in the cup and neuroretinal rim using stereoscopic color fundus images. Invest Ophthalmol Vis Sci 56(3):1562–1568CrossRefPubMedGoogle Scholar
  9. 9.
    Bambo MP, Garcia-Martin E, Gutierrez-Ruiz F et al (2015) Analysis of optic disk color changes in Alzheimer’s disease: a potential new biomarker. Clin Neurol Neurosurg 132:68–73CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Manuel Gonzalez-de-la-Rosa
    • 1
  • Marta Gonzalez-Hernandez
    • 1
  • Carmen Mendez-Hernandez
    • 2
  • Elena Garcia-Martin
    • 3
  • Francisco Fumero-Bautista
    • 4
  • Silvia Alayon
    • 4
  • Jose Sigut
    • 4
  1. 1.Department of OphthalmologyHospital Universitario de Canarias, University of La LagunaLa LagunaSpain
  2. 2.Department of OphthalmologyHospital Clinico San Carlos, University Complutense of MadridMadridSpain
  3. 3.Department of OphthalmologyHospital Universitario Miguel ServetZaragozaSpain
  4. 4.Department of Systems EngineeringUniversity of La LagunaLa LagunaSpain

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