Hand, Foot, and Mouth Disease

  • Danya Reich
  • Corinna Eleni Psomadakis
  • Bobby Buka


Hand, foot, and mouth disease (HFMD) is an enteroviral illness, typically of childhood, which causes painful vesicular lesions in the mouth, on the palms, and on the soles of the feet. HFMD is most commonly caused by coxsackievirus, though a more severe form can be caused by enterovirus 71. Typical HFMD is self-resolving within 7–10 days; however, physicians may provide supportive care and symptomatic relief in the form of oral anesthetics. After symptoms have resolved, patients may continue shedding viral particles for up to 5 weeks so contact precautions and good hygiene practices are recommended.


Hand, foot, and mouth disease HFMD Coxsackie Enterovirus Coxsackievirus A6 A16 Enterovirus 71 Fecal–oral transmission Pediatric Vesicles Virus Prodromal symptoms Malaise Fever Symptomatic relief Self limiting 


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Copyright information

© Springer International Publishing Switzerland 2017

Open Access This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Danya Reich
    • 1
  • Corinna Eleni Psomadakis
    • 2
  • Bobby Buka
    • 3
  1. 1.Department of Family MedicineMount Sinai School of Medicine Attending Mount Sinai Doctors/Beth Israel Medical Group-WilliamsburgBrooklynUSA
  2. 2.School of Medicine Imperial College LondonLondonUK
  3. 3.Department of DermatologyMount Sinai School of MedicineNew YorkUSA

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