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Lichen Simplex Chronicus

  • Danya Reich
  • Corinna Eleni Psomadakis
  • Bobby Buka
Chapter

Abstract

Lichen simplex chronicus is a secondary skin condition that occurs in response to severe pruritus, which drives an itch–scratch cycle. Individuals scratch the pruritic areas of the skin and cause them to become thickened, leathery plaques. The initial pruritus may be caused by atopy, or a number of underlying systemic illnesses such as renal or hepatic insufficiency, thyroid disorders, HIV, and lymphoma. Treating the underlying cause is an important element of treating lichen simplex chronicus. The symptoms may be addressed by use of topical corticosteroids or calcineurin inhibitors. Oral antihistamines may provide additional symptomatic relief.

Keywords

Itch–scratch cycle Pruritus Neurodermatitis Leathery skin Lichenification Liver failure Renal failure Renal insufficiency Topical steroid Calcineurin inhibitor Pimecrolimus Tacrolimus Antihistamine 

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Copyright information

© Springer International Publishing Switzerland 2017

Open Access This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Danya Reich
    • 1
  • Corinna Eleni Psomadakis
    • 2
  • Bobby Buka
    • 3
  1. 1.Department of Family MedicineMount Sinai School of Medicine Attending Mount Sinai Doctors/Beth Israel Medical Group-WilliamsburgBrooklynUSA
  2. 2.School of Medicine Imperial College LondonLondonUK
  3. 3.Department of DermatologyMount Sinai School of MedicineNew YorkUSA

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