• Danya Reich
  • Corinna Eleni Psomadakis
  • Bobby Buka


Onychomycosis is a common fungal infection of the nails, typically caused by the dermatophyte Trichophyton rubrum. The condition is often preceded by a fungal infection of the skin of the foot called tinea pedis. Onychomycosis causes the affected nail to thicken and typically develop a yellow discoloration. Oral antifungals are the most effective treatment for onychomycosis, which should be commenced after confirming the diagnosis via PAS staining and ensuring the patient has good liver function. Topical treatment is available in the form of ciclopirox or efinaconazole lacquers, which are safer yet less effective than oral antifungals.


Onychomycosis Dermatophytosis Dermatophyte Fungus Fungal infection Toenail Trichophyton rubrum Candida albicans Tinea pedis Yellow nail PAS stain Onycholysis Nail culture Jublia Ciclopirox Penlac Terbinafine Antifungal 


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© Springer International Publishing Switzerland 2017

Open Access This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Danya Reich
    • 1
  • Corinna Eleni Psomadakis
    • 2
  • Bobby Buka
    • 3
  1. 1.Department of Family MedicineMount Sinai School of Medicine Attending Mount Sinai Doctors/Beth Israel Medical Group-WilliamsburgBrooklynUSA
  2. 2.School of Medicine Imperial College LondonLondonUK
  3. 3.Department of DermatologyMount Sinai School of MedicineNew YorkUSA

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