Pompholyx, or dyshidrotic eczema, is a chronic dermatitis that mainly affects the hands and, less frequently, the feet. The condition causes highly pruritic vesicles to form on the palms and lateral aspects of the fingers, with some individuals experiencing a burning sensation. The etiology of pompholyx is thought to be multifactorial and is known to be exacerbated by a number of factors, including emotional stress, smoking, contact allergies, eczema, and compromised immune state. Treatment of pompholyx should aim to limit any known causal factors as well as address the inflammation seen in acute flares. Potent topical corticosteroids are first-line treatment. Individuals who do not respond to topical corticosteroids may be treated with a topical immunomodulators such as tacrolimus. The condition tends to be chronic and recurrent.
KeywordsDyshidrotic eczema Eczema Pompholyx Hand eczema Vesicles Vesicular dermatitis Chronic Topical steroid Corticosteroid Prednisone Phototherapy
- 5.Doshi DN, Cheng CE, Kimball AB. Chapter 16. Vesicular palmoplantar eczema. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick’s dermatology in general medicine. 8th ed. New York: McGraw-Hill; 2012. Available from: http://accessmedicine.mhmedical.com.ezproxy.cul.columbia.edu/content.aspx?bookid=392&Sectionid=41138711. Accessed 18 Nov 2014.Google Scholar