Skip to main content
SpringerLink
Log in

Brief Historical Overview of the Clinical Development of ReLEx® Surgical Procedure

  • Chapter
Small Incision Lenticule Extraction (SMILE)

  • 827 Accesses

Abstract

Corneal resectional refractive procedures for the correction of myopia were pioneered by Barraquer and Ruiz [1]. They removed a layer of intrastromal tissue utilizing a microkeratome and called this procedure “in situ keratomileusis.” However, the results of the procedure performed with mechanical devices were not entirely satisfactory [2, 3].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Barraquer JI (1996) The history and evolution of keratomileusis. Int Ophthalmol Clin 36:1–7

    Article  CAS  PubMed  Google Scholar 

  2. Ibrahim O, Waring GO, Salah T, el Maghraby A (1995) Automated in situ Keratomileusis for myopia. J Refract Surg 11:431–441

    CAS  PubMed  Google Scholar 

  3. Wiegand W, Krusenberg B, Kroll P (1995) Keratomileusis in situ bei hochgradiger Myopie. Erste Ergebnisse. Ophthalmologe 92:402–409

    CAS  PubMed  Google Scholar 

  4. Stern D, Schoenlein RW, Puliafito CA (1989) Corneal ablation by nanosecond, picoseconds, and femtosecond lasers at 532 and 625 nm. Arch Ophthalmol 107:567–592

    Article  Google Scholar 

  5. Ito M, Quantock AJ, Malhan S, Schanzlin DJ, Krueger RR (1996) Picosecond laser in situ keratomileusis with a 1053-nm Nd:YFL laser. J Refract Surg 12:721–728

    CAS  PubMed  Google Scholar 

  6. Krueger RR, Juhasz T, Gualano A, Marchi V (1998) The picosecond laser for nonmechanical laser in situ keratomileusis. J Refract Surg 14:467–469

    CAS  PubMed  Google Scholar 

  7. Kurtz RM, Horvath C, Liu HH, Krueger RR, Juhasz T (1998) Lamellar refractive surgery with scanned intrastromal picoseconds and femtosecond laser pulses in animal eyes. J Refract Surg 14:541–548

    CAS  PubMed  Google Scholar 

  8. Heisterkamp A, Mamon T, Kermani O, Drommer W, Welling H, Ertmer W, Lubatschowski H (2003) Intrastromal refractive surgery with ultrashort laser pulses: in vivo study on the rabbit eye. Graefes Arch Clin Exp Ophthalmol 241:511–517

    Article  PubMed  Google Scholar 

  9. Ratkay-Traub I, Ferincz IE, Juhasz T, Kurtz RM, Krueger RR (2003) First clinical results with the femtosecond neodymium-glass laser in refractive surgery. J Refract Surg 19:94–103

    PubMed  Google Scholar 

  10. Nordan LT, Slade SG, Baker RN (2003) Femtosecond laser flap creation for laser in situ keratomileusis: six-months follow-up of the initial US clinical series. J Refract Surg 19:8–14

    PubMed  Google Scholar 

  11. Kezirian GM, Stonecipher KG (2004) Comparison of the IntraLase femtosecond laser and mechanical microkeratome for laser in situ keratomileusis. J Cataract Refract Surg 30:26–32

    Article  Google Scholar 

  12. Durrie DS, Kezirian GM (2005) Femtosecond laser versus mechanical keratome flaps in wavefront-guided laser in situ keratomileusis: prospective contralateral eye study. J Cataract Refract Surg 31:120–126

    Article  PubMed  Google Scholar 

  13. Tran DB, Sarayba MA, Bor Z et al (2005) Randomized prospective clinical study comparing induced aberrations with IntraLase and Hansatome flap creation in fellow eyes: potential impact on wavefront-guided laser in situ keratomileusis. J Cataract Refract Surg 31:97–105

    Article  PubMed  Google Scholar 

  14. Vetter JM, Holzer MP, Teping C, Weingartner WE, Gericke A, Stoffelns B, Pfeiffer N, Sekundo W (2011) Intraocular pressure during corneal flap preparation: comparison among four femtosecond lasers in porcine eyes. J Refract Surg 27:427–433

    Article  PubMed  Google Scholar 

  15. Vetter JM, Faust M, Gericke A, Pfeiffer N, Weingärtner WE, SEkundo W (2012) Intraocular pressure measurements during flap preparation using 2 femtosecond lasers and 1 microkeratome in human donor eyes. J Cataract Refract Surg 38:2011–2018

    Article  PubMed  Google Scholar 

  16. Sekundo W, Gertnere J, Bertelmann T, Solomatin I (2014) One-year refractive results, contrast sensitivity, high-order aberrations and complications after myopic small-incision lenticule extraction (ReLEx SMILE). Graefes Arch Clin Exp Ophthalmol 252(5):837–843

    Article  PubMed  Google Scholar 

  17. Reviglio VE, Kuo IC, Gramajo L et al (2007) Acute rhegmatogenous retinal detachment immediately following laser in situ keratomileusis. J Cataract Refract Surg 33:536–539

    Article  PubMed  Google Scholar 

  18. Blum M, Kunert K, Gille A, Sekundo W (2009) First experience in femtosecond LASIK with the Zeiss VISUMAX® laser. J Refract Surg 25:350–356

    Article  PubMed  Google Scholar 

  19. Sekundo W, Kunert K, Russmann C, Gille A, Bissmann W, Strobrawa G, Stickler M, Bischoff M, Blum M (2008) First efficacy and safety study of femtosecond lenticule extraction for the correction of myopia. J Cataract Refract Surg 34:1513–1520

    Article  PubMed  Google Scholar 

  20. Blum M, Kunert K, Schröder M, Sekundo W (2010) Femtosecond lenticule extraction (FLEX) for the correction of myopia: 6 months results. Graefes Arch Clin Exp Ophthalmol 248:1019–1027

    Article  PubMed  Google Scholar 

  21. Blum M, Kunert KS, Engelbrecht C, Dawczynski J, Sekundo W (2010) Femtosekunden-Lentikel-Extraktion (FLEX) – Ergebnisse nach 12 Monaten bei myopem Astigmatismus. Klin Monatsbl Augenheilkd 227:961–965

    Article  CAS  PubMed  Google Scholar 

  22. Blum M, Flach A, Kunert KS, Sekundo W (2014) Five-year results of refractive lenticule extraction. J Cataract Refract Surg 40:1425–1429

    Article  PubMed  Google Scholar 

  23. Shah R, Shah S (2011) Effect of scanning patterns on the results of femtosecond laser lenticule extraction refractive surgery. J Cataract Refract Surg 37:1636–1647

    Article  PubMed  Google Scholar 

  24. Sekundo W, Kunert K, Blum M (2011) Small incision femtosecond lenticule extraction (SMILE) for the correction of myopia and myopic astigmatism: results of a 6 months prospective study. Br J Ophthalmol 95:335–339

    Article  PubMed  Google Scholar 

  25. Shah R, Shah S, Segupta S (2011) Results of small incision lenticule extraction: all-in-one femtosecond laser refractive surgery. J Cataract Refract Surg 37:127–137

    Article  PubMed  Google Scholar 

  26. Hjortdal JO, Vestergaard AH, Ivarsen A, Ragunathan S, Asp S (2012) Predictors for the outcome of small-incision lenticule extraction for Myopia. J Refract Surg 28:865–871

    Article  PubMed  Google Scholar 

  27. Kamiya K, Shimizu K, Igarashi A, Kobashi H (2014) Visual and refractive outcomes of femtosecond lenticule extraction and small-incision lenticule extraction for myopia. Am J Ophthalmol 157:128–134

    Article  PubMed  Google Scholar 

  28. Kunert KS, Blum M, Duncker GIW, Sietmann R, Heichel J (2011) Surface quality of human corneal lenticules after femtosecond laser surgery for myopia comparing different laser parameters. Graefes Arch Clin Exp Ophthalmol 249:1417–1424

    Article  PubMed  Google Scholar 

  29. Heichelt J, Blum M, Duncker GIW, Sietmann R, Kunert KS (2011) Surface quality of porcine corneal lenticules after Femtosecond Lenticule Extraction. Ophthalmic Res 46:107–112

    Article  Google Scholar 

  30. Reinstein DZ, Archer TJ, Gobbe M (2013) Accuracy and reproducibility of cap thickness in small incision lenticule extraction. J Refract Surg 29:810–815

    Article  PubMed  Google Scholar 

  31. Ozgurhan EB, Agca A, Bozkurt E, Gencer B, Celik U, Cankaya KI, DEmirok A, Yilmaz OF (2013) Accuracy and precision of cap thickness in small incision lenticule extraction. Clin Ophthalmol 7:923–926

    PubMed Central  PubMed  Google Scholar 

  32. Ivarsen A, Asp S, Hjortdal J (2014) Safety and complications of more than 1500 small incision lenticule extraction procedures. Ophthalmology 121:822–882

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Helios Hospital Erfurt, Erfurt, Germany

    Marcus Blum MD

  2. Department of Ophthalmology, Philipps University of Marburg and Universitätsklinikum Giessen & Marburg GmbH, Marburg, Germany

    Walter Sekundo MD

Authors
  1. Marcus Blum MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Walter Sekundo MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Marcus Blum MD .

Editor information

Editors and Affiliations

  1. Department of Ophthalmology, Philipps University of Marburg, Marburg, Germany

    Walter Sekundo

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Blum, M., Sekundo, W. (2015). Brief Historical Overview of the Clinical Development of ReLEx® Surgical Procedure. In: Sekundo, W. (eds) Small Incision Lenticule Extraction (SMILE). Springer, Cham. https://doi.org/10.1007/978-3-319-18530-9_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-18530-9_4

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18529-3

  • Online ISBN: 978-3-319-18530-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation