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General Principles of Cancer Chemotherapy

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Pediatric Cancer in Africa

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Learning Objectives

By the end of this chapter, you will be able to:

  • Describe the cell cycle and basic concepts regarding tumor growth

  • Name the different classes of chemotherapeutic agents

  • Understand the mechanisms of action of the chemotherapeutic agents used most often in the treatment of childhood cancer

  • Discuss the requirements and precautions for the safe administration of chemotherapy

  • Discuss the toxicity of chemotherapy and the preventive measures that should be taken

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Suggested Reading

  • Adamson PC, Bagatelli R, Balis FM, Blaney SM (2014) General principles of chemotherapy. In: Pizzo PA, Poplack GD (eds) Principles and practices of paediatric oncology, 6th edn. Lippincott Williams & Wilkins, Philadelphia, pp 279–355

    Google Scholar 

  • http://chemoth.com/types

  • Neuss MN, Polovich M, McNiff K, Gilmore TR, LeFebvre KB, Schulmeister L, Jacobson JO (2013) Updated American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety Standards Including Standards for the Safe Administration and Management of Oral Chemotherapy. Oncol Nurs Forum 40(3):225–233

    Article  PubMed  Google Scholar 

  • Safe handling of hazardous chemotherapy drugs in limited-resource settings (2013). A WHO and PAHO publication. www.paho.org

  • Taʂkin-Tok T, Gowder S Anticancer drug—friend or foe. Chapter 9. http://www.intechopen.com/books/pharmacology-and-therapeutics

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Author information

Authors and Affiliations

  1. South African Medical Research Council, Cape Town, South Africa

    Daniela Cristina Stefan

  2. Université Mohammed VI des Sciences de la Santé Cheikh Khalifa Hospital, Casablanca, Morocco

    Mhamed Harif

Authors
  1. Daniela Cristina Stefan
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  2. Mhamed Harif
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Stefan, D.C., Harif, M. (2017). General Principles of Cancer Chemotherapy. In: Pediatric Cancer in Africa. Springer, Cham. https://doi.org/10.1007/978-3-319-17936-0_23

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  • DOI: https://doi.org/10.1007/978-3-319-17936-0_23

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17935-3

  • Online ISBN: 978-3-319-17936-0

  • eBook Packages: MedicineMedicine (R0)

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