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Clinical Research and Patient Participation

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Subarachnoid Hemorrhage in Clinical Practice

Part of the book series: In Clinical Practice ((ICP))

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Abstract

This handbook is based on clinical research in patients with an aneurysm or subarachnoid hemorrhage. Clinical research is unthinkable without patients’ willingness to participate, and their collaboration is of great importance not only to improve knowledge on causes, diagnosis, prognosis and therapy of subarachnoid hemorrhage and intracranial aneurysms but also to obtain new ideas.

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References

  1. Nieuwkamp DJ, Setz LE, Algra A, Linn FH, de Rooij NK, Rinkel GJE. Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol. 2009;8(7):635–42.

    Google Scholar 

  2. van der Schaaf IC, Algra A, Wermer MJ, Molyneux AJ, Clarke M, van Gijn J, et al. Endovascular coiling versus neurosurgical clipping for patients with aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2005;(4):CD003085.

    Google Scholar 

  3. Molyneux AJ, Birks J, Clarke A, Sneade M, Kerr RS. The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT). Lancet. 2015;385(9969):691–7.

    Article  PubMed Central  PubMed  Google Scholar 

  4. van Doormaal TP, van der Zwan A, Verweij BH, Regli L, Tulleken CA. Giant aneurysm clipping under protection of an excimer laser-assisted non-occlusive anastomosis bypass. Neurosurgery. 2010;66(3):439–47.

    Article  PubMed  Google Scholar 

  5. Dashti R, Laakso A, Niemela M, Porras M, Hernesniemi J. Microscope-integrated near-infrared indocyanine green videoangiography during surgery of intracranial aneurysms: the Helsinki experience. Surg Neurol. 2009;71(5):543–50.

    Article  PubMed  Google Scholar 

  6. Sarker SJ, Heuschmann PU, Burger I, Wolfe CD, Rudd AG, Smeeton NC, et al. Predictors of survival after haemorrhagic stroke in a multi-ethnic population: the South London Stroke Register (SLSR). J Neurol Neurosurg Psychiatry. 2008;79(3):260–5.

    Article  CAS  PubMed  Google Scholar 

  7. Schaafsma JD, Koffijberg H, Buskens E, Velthuis BK, van der Graaf Y, Rinkel GJE. Cost-effectiveness of magnetic resonance angiography versus intra-arterial digital subtraction angiography to follow-up patients with coiled intracranial aneurysms. Stroke. 2010;41(8):1736–42.

    Article  PubMed  Google Scholar 

  8. Schaafsma JD, Velthuis BK, van den Berg R, Brouwer PA, Majoie CB, Barkhof F, et al. Coil-treated aneurysms: decision making regarding additional treatment based on findings of MR angiography and intraarterial DSA. Radiology. 2012;265(3):858–63.

    Article  PubMed  Google Scholar 

  9. Wermer MJ, Greebe P, Algra A, Rinkel GJE. Incidence of recurrent subarachnoid hemorrhage after clipping for ruptured intracranial aneurysms. Stroke. 2005;36(11):2394–9.

    Article  PubMed  Google Scholar 

  10. Wermer MJ, van der Schaaf IC, Velthuis BK, Algra A, Buskens E, Rinkel GJE. Follow-up screening after subarachnoid haemorrhage: frequency and determinants of new aneurysms and enlargement of existing aneurysms. Brain. 2005;128:2421–9.

    Google Scholar 

  11. Wermer MJ, Koffijberg H, van der Schaaf IC. Effectiveness and costs of screening for aneurysms every 5 years after subarachnoid hemorrhage. Neurology. 2008;70(22):2053–62.

    Article  PubMed  Google Scholar 

  12. Bor AS, Rinkel GJE, van Norden J, Wermer MJ. Long-term, serial screening for intracranial aneurysms in individuals with a family history of aneurysmal subarachnoid haemorrhage: a cohort study. Lancet Neurol. 2014;13(4):385–92.

    Google Scholar 

  13. Greving JP, Wermer MJ, Brown Jr RD, Morita A, Juvela S, Yonekura M, et al. Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies. Lancet Neurol. 2014;13(1):59–66.

    Article  PubMed  Google Scholar 

  14. Bromberg JEC, Rinkel GJE, Algra A, Greebe P, van Duyn CM, Hasan D, et al. Subarachnoid haemorrhage in first and second degree relatives of patients with subarachnoid haemorrhage. BMJ. 1995;311:288–9.

    Google Scholar 

  15. MARS Study Group. Risks and benefits of screening for intracranial aneurysms in first-degree relatives of patients with sporadic subarachnoid hemorrhage. N Engl J Med. 1999;341:1344–50.

    Article  Google Scholar 

  16. Rasing I, Ruigrok YM, Greebe P, Velthuis BK, Witkamp TD, Wermer MJ, et al. Long-term risk of aneurysmal subarachnoid hemorrhage after a negative aneurysm screen. Neurology. 2015;84(9):912–7.

    Article  PubMed  Google Scholar 

  17. Germans MR, Post R, Coert BA, Rinkel GJE, Vandertop WP, Verbaan D. Ultra-early tranexamic acid after subarachnoid hemorrhage (ULTRA): study protocol for a randomized controlled trial. Trials. 2013;14(1):143.

    Article  PubMed Central  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, Utrecht, The Netherlands

    Gabriel J. E. Rinkel & Paut Greebe

Authors
  1. Gabriel J. E. Rinkel
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  2. Paut Greebe
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© 2015 Springer International Publishing Switzerland

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Rinkel, G.J.E., Greebe, P. (2015). Clinical Research and Patient Participation. In: Subarachnoid Hemorrhage in Clinical Practice. In Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-17840-0_7

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  • DOI: https://doi.org/10.1007/978-3-319-17840-0_7

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17839-4

  • Online ISBN: 978-3-319-17840-0

  • eBook Packages: MedicineMedicine (R0)

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