Abstract
Surface modification approaches can be mainly regarded as by either a physical or a chemical means (note the biological ones are considered as a subset of chemical ones), or both. This chapter focuses on the physical means, particularly, a morphological approach to surface modification. Through illustration of how the area of a planar surface can be increased significantly by adding nanoscopic structures to the surface and that most of these nanostructures may be deemed useless for biosensor applications, it argues for a particular need of biosensors, namely, the need for aqua-robust nanostructures having the highest exposed surface area possible. Following that, it presents with full technical detail the processes to form aqua-robust nanopillar structures along with brief discussions on the underlying science. All the discussions are in the form of case studies, thus providing a practical guide for readers who might want to develop similar surfaces. This chapter ends with, again, a detailed discussion of a recently patented procedure on how to form integrated micro and nano structures on-a-chip for possible biosensor applications.
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Zhang, G. (2015). Morphological Surface Modification. In: Nanoscale Surface Modification for Enhanced Biosensing. Springer, Cham. https://doi.org/10.1007/978-3-319-17479-2_2
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DOI: https://doi.org/10.1007/978-3-319-17479-2_2
Publisher Name: Springer, Cham
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