Abstract
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a cytotoxic T-cell lymphoma with an excellent prognosis. Patients present with recurrent, generally painless, erythematous subcutaneous tumors on the trunk and extremities, often followed by lipoatrophy. Of note, this diagnosis previously encompassed two different diseases: lymphomas composed of alpha/beta-type T cells and lymphomas of gamma/delta T cells [1]. In the most recent WHO-EORTC guidelines, these have now been separated into SPTCL and primary cutaneous gamma/delta T-cell lymphoma (pcGDTCL), respectively [2]. Older studies, which lumped together both the alpha/beta and gamma/delta lymphomas, may report lower 5-year survival rates and poorer prognosis, reflecting the more aggressive course of pcGDTCL. This chapter discusses the clinical presentation, prognosis, and treatment of SPTCL, as well as its histopathology and immunohistochemistry. The chapter closes with a differential diagnosis and a clinical case.
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Goyal, A., Carter, J.B., Duncan, L.M. (2015). Subcutaneous Panniculitis-Like T-Cell Lymphoma. In: Carter, J., Goyal, A., McDivitt Duncan, L. (eds) Atlas of Cutaneous Lymphomas. Springer, Cham. https://doi.org/10.1007/978-3-319-17217-0_8
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DOI: https://doi.org/10.1007/978-3-319-17217-0_8
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