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Primary Cutaneous Marginal Zone Lymphoma

  • Amrita Goyal
  • Joi B. Carter
  • Jeffrey A. Barnes
  • Lyn McDivitt DuncanEmail author
Chapter

Abstract

Primary cutaneous marginal zone lymphoma (pcMZL) is an indolent B-cell lymphoma that commonly presents with red to violaceous plaques, nodules, or tumors. It has an excellent prognosis. This entity has also been known as cutaneous marginal zone lymphoma (CMZL), extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MZL or MALT lymphoma), primary cutaneous immunocytoma, primary cutaneous plasmacytoma, and lymphoma cutis [1, 2]. This chapter will discuss the clinical presentation, prognosis, treatment, histopathology, immunophenotype, and differential diagnosis of pcMZL. It closes with a clinical case, including clinical images and histopathology.

Keywords

Extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT, MZL) Cutaneous marginal zone lymphoma Primary cutaneous marginal zone lymphoma (pcMZL) Centrocyte Monocytoid B cells Lymphoplasmacytoid cells Plasmacytic differentiation Reactive germinal centers Lymphoepithelial lesions 

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Amrita Goyal
    • 1
  • Joi B. Carter
    • 2
  • Jeffrey A. Barnes
    • 3
  • Lyn McDivitt Duncan
    • 4
    Email author
  1. 1.Harvard-MIT Division of Health Sciences and TechnologyHarvard Medical SchoolBostonUSA
  2. 2.Department of DermatologyMassachusetts General Hospital, Harvard Medical SchoolBostonUSA
  3. 3.Comprehensive Cutaneous Lymphoma Program, Department of MedicineMassachusetts General Hospital Cancer CenterBostonUSA
  4. 4.Dermatopathology Service, Department of PathologyMassachusetts General Hospital, Harvard Medical SchoolBostonUSA

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