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Intussusception

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Textbook of Pediatric Gastroenterology, Hepatology and Nutrition

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Abstract

Intussusception represents the most common cause of gastrointestinal obstruction in children aged between 3 months and 3 years. It is the second most frequent acute abdominal surgical emergency in pediatrics after acute appendicitis. Left untreated, intussusception can have serious, potentially life-threatening sequelae. All clinicians involved in the assessment and care of pediatric patients should therefore have a sound understanding of this condition and its management. This chapter provides a comprehensive clinical overview of intussusception, including its pathogenesis, etiology, classification, presentation, epidemiology, diagnosis, management, and prognosis.

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References

  1. Davis CF, McCabe AJ, Raine PAM. The ins and outs of intussusception: history and management over the past fifty years. J Paediatr Surg. 2003;38 (Suppl 7):60–4.

    Article  CAS  Google Scholar 

  2. R obb A, Lander A. Intussusception in infants and young children. Surgery 2008;26(7):291–3.

    Google Scholar 

  3. Saliakellis E, Borrelli O, Thapar N. Paediatric GI emergencies. Best Pract Res Clin Gastroenterol. 2013;27(5):799–817.

    Article  PubMed  Google Scholar 

  4. Morrison SC, Stork E. Documentation of spontaneous reduction of childhood intussusception by ultrasound. Paediatr Radiol. 1990;20(5):358–9.

    Article  CAS  Google Scholar 

  5. Jung C, Hugot J, Barreau F. Payer’s patches: the immune sensors of the intestine. Int J Inflam. 2010;2010:823710. (published online 19/09/2010).

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  6. Bines JE, Liem NT, Justice FA, Son TN, Kirkwood CD, de Campo M, et al. Risk factors for intussusception in infants in Vietnam and Australia: adenovirus implicated, but not rotavirus. J Paediatr. 2006;149(4):452.

    Article  Google Scholar 

  7. Patel MM, Haber P, Baggs J, Zuber P, Bines JE, Parashar UD. Intussusception and rotavirus vaccination: a review of the available evidence. Expert Rev Vaccines. 2009;8(11):1555–64.

    Article  PubMed  Google Scholar 

  8. Nyland CM, Denson LA, Noel JM. Bacterial enteritis as a risk factor for childhood intussusception: a retrospective cohort study. J Paediatr. 156(5):761.

    Google Scholar 

  9. Milbrandt K, Sigalet D. Intussusception associated with a Meckel’s diverticulum and a duplication cyst. J Paediatr Surg. 2008;43(12):e21–3.

    Article  Google Scholar 

  10. Howard N, Pranesh N, Carter P. Colo-colonic intussusception secondary to a lipoma, Int. J Surg Case Rep. 2012;3(2):52–4.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Brichon P, Bertrand Y, Plantaz D. Burkitt’s lymphoma revealed by acute intussusception in children. Ann Chir. 2001;126(7):649–53.

    Article  PubMed  CAS  Google Scholar 

  12. Sasaki T, Fukumori D, Sato M, Sakai K, Ohmori H, Yamamato F. Peutz–Jeghers syndrome associated with intestinal intussusception: a case report. Int Surg. 2002;87(4):256–9.

    PubMed  Google Scholar 

  13. Verma S, Bawa M, Rao K et al. BMJ Case Rep. 2013. doi:10.1136/ bcr-2012-008056.

    Google Scholar 

  14. Deigaard SB, Trap R. Intestinal duplication—an important differential diagnosis to intussusception. Ugeskr Laeger. 2008;170(35):2708.

    Google Scholar 

  15. Nash EF, Stephenson A, Helm EJ, Ho T, Thippanna CM, Ali A, et al. Intussusception in adults with cystic fibrosis: a case series with review of the literature. Dig Dis Sci. 2011;56(12):3695–700.

    Article  PubMed  Google Scholar 

  16. Lu S, Goh P. Traumatic intussusception with intramural haematoma. Paediatr Radiol. 2009;39(4):403–5.

    Article  Google Scholar 

  17. Chang WL, Yang YH, Lin YT, Chiang BL. Gastrointestinal manifestations in Henoch–Schonlein purpura: a review of 261 patients. Acta Paediatr. 2004;93(11):1427–31.

    Article  PubMed  Google Scholar 

  18. Dalshaug GB, Wainer S, Hollaar GL. The Rapunzel syndrome (Trichobezoar) causing atypical intussusception in a child: a case report. J Paediatr Surg. 1999;34(3):479–80.

    Article  CAS  Google Scholar 

  19. Guthrie SO, Rhodes M, Janco R, Stein, SM, Jabs K, Engelhardt B. An infant with Kasabach–Merritt syndrome with associated renal haematoma and intussusception. J Perinatol. 2005;25:143–5.

    Article  PubMed  Google Scholar 

  20. Ramdial PK, Sing Y, Hadley GP, Chotey NA, Mahlakwane MS, Singh B. Paediatric intussusception caused by acquired immunodeficiency syndrome-associated Kaposi sarcoma. Paediatr Surg Int. 2010;26(8):783–87.

    Article  Google Scholar 

  21. Earl TM, Wellen JR, Anderson CD, Nadler M, Doyle MM, Shenoy SS, et al. Small bowel obstruction after paediatric liver transplantation: the unusual is the usual. J Am Coll Surg. 2011;212(1):62–7.

    Article  PubMed  Google Scholar 

  22. Furuya Y, Wakahara T, Akimoto H, Long CM, Yanagie H, Yasuhara H. A case of postoperative recurrent intussusception associated with indwelling bowel tube. World J Gastrointest Surg. 2010;2(3):85–8.

    Article  PubMed Central  PubMed  Google Scholar 

  23. Yang G, Wang X, Jiang W, Ma J, Zhao J, Liu W. Postoperative intussusception in children and infants: a systematic review. Paediatr Surg Int. 29:1273–9.

    Google Scholar 

  24. Jiang J, Jiang B, Parashar U, Nguyen T, Bines J, Patel MM. Childhood intussusception: a literature review. PLoS One. 2013;8(7):e68482.

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  25. Nguyen DT, Lai E, Cunningham T, and Moore TC. In utero intussusception producing ileal atresia and meconium peritonitis with and without free air. Paediatr Surg Int. 1995;10(5–6):406–8.

    Google Scholar 

  26. Huebner BR, Azarow KS, Cusick RA. Intestinal atresia due to intrauterine intussusception of a Meckel’s diverticulum. J Paediatr Surg Case Rep. 2013;1(8):232–4.

    Article  Google Scholar 

  27. Samad L, Cortina-Borja M, El Bashir H, Sutcliffe AG, Marven S, Cameron JC, et al. Intussusception incidence among infants in the UK and Republic of Ireland: a pre- rotavirus vaccine prospective surveillance study. Vaccine 2013;31(38):4098–102.

    Article  PubMed Central  PubMed  Google Scholar 

  28. Wong KB, Lui CT, Fung HT. How do adult and paediatric intussusceptions differ? A 10-year retrospective study. Hong Kong J Emerg Med. 2012;19(4).

    Google Scholar 

  29. Marinis A, Yiallourou A, Samanides L, Dafnios N, Anastasopoulos G, Vassiliou J, et al. Intussusception of the bowel in adults: a review. World J Gastroenterol. 2009;15(4):407–11.

    Article  PubMed Central  PubMed  Google Scholar 

  30. Erkan N, Haciyanli M, Yildirim M, Sayhan H, Vardar E, Polat AF. Intussusception in adults: an unusual and challenging condition for surgeons. Int J Colorectal Dis. 2005;20(5):452.

    Article  PubMed  Google Scholar 

  31. Tate JE, Simonsen L, Viboud C, Steiner C, Patel MM, Curns AT, et al. Trends in intussusception hospitalizations among US infants, 1993–2004: implications for monitoring the safety of the new rotavirus vaccination program. Pediatrics 2008;121(5):e1125–32.

    Article  PubMed Central  PubMed  Google Scholar 

  32. Justice F, Carlin J, Bines J. Changing epidemiology of intussusception in Australia. J Paediatr Child Health. 2005;41(9–10):475–8.

    Article  PubMed  Google Scholar 

  33. Webby RJ, Bines J, Barnes GL, Tindall H, Krause V, Patel M. Intussusception in the Northern Territory: the incidence is low in Aboriginal and Torres Strait Islander children. J Paediatr Child Health. 2006;42(5):235–9.

    Article  PubMed  Google Scholar 

  34. http://whqlibdoc.who.int/hq/2002/WHO_V&B_02.19.pdf. Accessed 12 Dec 2013.

  35. Takeuchi M, Osamura T, Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S. Intussusception among Japanese children: an epidemiologic study using an administrative database. BMC Pediatr. 2012;12:36.

    Article  PubMed Central  PubMed  Google Scholar 

  36. Boudville IC, Phua KB, Quak SH, Lee BW, Han HH, Verstraeten T, et al. The epidemiology of paediatric intussusception in Singapore: 1997–2004. Ann Acad Med Singapore. 2006;35(10):674–9.

    PubMed  Google Scholar 

  37. Rennels MB, Parashar UD, Homlam RC, Le CT, Chang HG, Glass RI. Lack of an apparent association between intussusception and wild or vaccine rotavirus infection. Pediatr Infect Dis J. 1998;17:924–5.

    Article  PubMed  CAS  Google Scholar 

  38. Mandeville K, Chien M, Willyerd FA, Mandell G, Hostetler MA, Bulloch B. Intussusception: clinical presentations and imaging characteristics. Pediatr Emerg Care. 2012;28(9):842–4.

    Article  PubMed  Google Scholar 

  39. Hutson JM, O’Brien M, Woodward AA, Beasley SW, editors. Jones’ clinical paediatric surgery. 6th ed. Oxford: Blackwell; 2008.

    Book  Google Scholar 

  40. http://www.hawaii.edu/medicine/pediatrics/pedtext/s10c04.html. Accessed 12 Dec 2013.

  41. Byrne AT, Geoghegan T, Govender P, Lyburn ID, Colhoun E, Torreggiani WC. The imaging of intussusception. Clin Radiol. 2005;60(1):39–46.

    Article  PubMed  CAS  Google Scholar 

  42. Shehata S, El Kholi N, Sultan A, El Sahwi E. Hydrostatic reduction of intussusception: barium, air, or saline. Pediatr Surg Int. 2000;16(5–6):380–2.

    Article  PubMed  CAS  Google Scholar 

  43. Nayak D, Jagdish S. Ultrasound guided hydrostatic reduction of intussusception in children by saline enema: our experience. Indian J Surg. 2008;70(1):8–13.

    Article  PubMed Central  PubMed  Google Scholar 

  44. Apelt N, Featherstone N, Giuliani S. Laparoscopic treatment of intussusception in children: a systematic review. J Paediatr Surg. 2013;48(8):1789–93.

    Article  Google Scholar 

  45. Hill SJ, Koontz CS, Langness SM, Wulkan ML. Laparoscopic versus open reduction of intussusception in children: experience over a decade. J Laproendosc Adv Surg Tech. 2013;23(2):166–9.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Pediatric Surgery, King’s College Hospital, Denmark Hill, SE5 9RS, London, UK

    Lydia O’Sullivan & Ashish P. Desai

Authors
  1. Lydia O’Sullivan
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  2. Ashish P. Desai
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Correspondence to Ashish P. Desai .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, University of Chicago, Chicago, Illinois, USA

    Stefano Guandalini

  2. Clinical Director Child Health King’s College Hospital, Professor and Director Pediatric Liver, GI and Nutrition Center, London, United Kingdom

    Anil Dhawan

  3. Department of Pediatrics, Hebrew University Hadassah Hospital, Jerusalem, Israel

    David Branski

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O’Sullivan, L., Desai, A. (2016). Intussusception. In: Guandalini, S., Dhawan, A., Branski, D. (eds) Textbook of Pediatric Gastroenterology, Hepatology and Nutrition. Springer, Cham. https://doi.org/10.1007/978-3-319-17169-2_48

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  • DOI: https://doi.org/10.1007/978-3-319-17169-2_48

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17168-5

  • Online ISBN: 978-3-319-17169-2

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