Advertisement

Living Donor Nephrectomy

  • Matteo RavaioliEmail author
  • Flavia F. Neri
  • Lorenzo Maroni
  • Massimo Del Gaudio
  • Annalisa Amaduzzi
  • Giorgio Ercolani
  • Antonio Daniele Pinna

Abstract

Kidney transplantation (KT) is the principal treatment of end-stage renal disease (ESRD) because it improves patient survival and quality of life compared to dialysis.

Living kidney donation (LKD) is the main strategy to overcome the organ shortage since the procedure is relatively safe for the donors and has improved graft survival with respect to cadaveric kidney donation (CKD).

There are many different surgical techniques for living donor nephrectomy, and over the years laparoscopic nephrectomy became advocated by many high-volume centers, but donor safety and recipient outcome still remain the principal end points for any surgical strategy.

Concluding, an open minimally invasive or laparoscopic approach is now considered the best option for living donor nephrectomy. The choice between minimal invasive and laparoscopic, and between the different laparoscopic techniques, should be based on the local expertise of the surgeons.

Keywords

Kidney transplantation Living kidney donation Laparoscopic approach Cadaveric kidney donation Surgical techniques 

References

  1. 1.
    Ratner LE, Ciseck LJ, Moore RG, et al. Laparoscopic live donor nephrectomy. Transplantation. 1995;60:1047–9.PubMedGoogle Scholar
  2. 2.
    Wolf Jr JS, Tchetgen MB, Merion RM. Hand-assisted laparoscopic live donor nephrectomy. Urology. 1998;52:885–7.CrossRefPubMedGoogle Scholar
  3. 3.
    Gill IS, Rassweiler JJ. Retroperitoneoscopic renal surgery: our approach. Urology. 1999;54:734–8.CrossRefPubMedGoogle Scholar
  4. 4.
    Wadstrom J, Lindstrom P. Hand-assisted retroperitoneoscopic living donor nephrectomy; initial 10 cases. Transplantation. 2002;73:1839–40.CrossRefPubMedGoogle Scholar
  5. 5.
    Matas AJ, Bartlett ST, Leichtman AB, Delmonico FL. Morbidity and mortality after living kidney donation, 1999–2001: survey of United States transplant centers. Am J Transplant. 2003;3:830–4.PubMedGoogle Scholar
  6. 6.
    Wilson CH, Sanni A, Rix DA, Soomro NA. Laparoscopic versus open nephrectomy for live kidney donors. Cochrane Database Syst Rev. 2011 Nov 9;(11):CD006124.  doi: 10.1002/14651858.CD006124.pub2.
  7. 7.
    Nephrol Dial Transplant. European Renal Best Practice Transplantation Guideline Development Group. 2013;28: ii1–71 doi:  10.1093/ndt/gft218 http://ndt.oxfordjournals.org/ at Oxford Journals on 4 Oct 2013.
  8. 8.
    Minnee RC, Idu MM. Laparoscopic donor nephrectomy. Neth J Med. 2010;68(5):199–206.PubMedGoogle Scholar
  9. 9.
    Tanabe K, Miyamoto N, Ishida H, et al. Retroperitoneoscopic live donor nephrectomy (RPLDN): establishment and initial experience of RPLDN at a single center. Am J Transplant. 2005;5:739.CrossRefPubMedGoogle Scholar
  10. 10.
    Maartense S, Idu M, Bemelman FJ, Balm R, Surachno S, Bemelman WA. Hand-assisted laparoscopic live donor nephrectomy. Br J Surg. 2004;91(3):344–8.CrossRefPubMedGoogle Scholar
  11. 11.
    Wadstrom J. Hand-assisted retroperitoneoscopic live donor nephrectomy: experience from the first 75 consecutive cases. Transplantation. 2005;80:1060.CrossRefPubMedGoogle Scholar
  12. 12.
    Horgan S, Benedetti E, Moser F. Robotically assisted donor nephrectomy for kidney transplantation. Am J Surg. 2004;188(4A Suppl):45S–51.CrossRefPubMedGoogle Scholar
  13. 13.
    Giacomoni A, Di Sandro S, Lauterio A, et al. Evolution of robotic nephrectomy for living donation: from hand-assisted to totally robotic technique. Int J Med Robot. 2014;10(3):286–93.Google Scholar
  14. 14.
    Kaouk JH, Khalifeh A, Laydner H, et al. Transvaginal hybrid natural orifice transluminal surgery robotic donor nephrectomy: first clinical application. Urology. 2012;80(6):1171–5.CrossRefPubMedGoogle Scholar
  15. 15.
    Fonouni H, Mehrabi A, Golriz M, et al. Comparison of the laparoscopic versus open live donor nephrectomy: an overview of surgical complications and outcome. Langenbecks. 2014;399(5):543–51.CrossRefGoogle Scholar
  16. 16.
    Banga N, Nicol D. Techniques in laparoscopic donor nephrectomy. BJU Int. 2012;110(9):1368–73.CrossRefPubMedGoogle Scholar
  17. 17.
    Dols LF, Kok NF, d’Ancona FC, et al. Randomized controlled trial comparing hand-assisted retroperitoneoscopic versus standard laparoscopic donor nephrectomy. Transplantation. 2014;97(2):161–7.CrossRefPubMedGoogle Scholar
  18. 18.
    Liu N, Wazir R, Wang J, Wang KJ. Maximizing the donor pool: left versus right laparoscopic live donor nephrectomy-systematic review and meta-analysis. Int Urol Nephrol. 2014;46(8):1511–9.CrossRefPubMedGoogle Scholar
  19. 19.
    Omoto K, Nozaki T, Inui M, et al. Impact of right-sided nephrectomy on long-term outcomes in retroperitoneoscopic live donor nephrectomy at single center. J Transplant. 2013;2013:546373.PubMedCentralCrossRefPubMedGoogle Scholar
  20. 20.
    Chedid MF, Muthu C, Nyberg SL, et al. Living donor kidney transplantation using laparoscopically procured multiple renal artery kidneys and right kidneys. J Am Coll Surg. 2013;217(1):144–52.CrossRefPubMedGoogle Scholar
  21. 21.
    Hamidi V, Andersen MH, Oyen O, et al. Cost effectiveness of open versus laparoscopic living-donor nephrectomy. Transplantation. 2009;87(6):831–8.CrossRefPubMedGoogle Scholar
  22. 22.
    Florian TF. Laparoscopic living donor nephrectomy: making optimal use of donors without doing harm. Transplantation 2014;15;98(11):1144.Google Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Matteo Ravaioli
    • 1
    Email author
  • Flavia F. Neri
    • 1
  • Lorenzo Maroni
    • 2
  • Massimo Del Gaudio
    • 1
  • Annalisa Amaduzzi
    • 1
  • Giorgio Ercolani
    • 3
  • Antonio Daniele Pinna
    • 3
  1. 1.Department of General Surgery and TransplantationSant’Orsola-Malpighi Hospital, University of BolognaBolognaItaly
  2. 2.Division of General and Transplant SurgeryUniversity of BolognaBolognaItaly
  3. 3.Department of Medical and Surgical SciencesSant’Orsola-Malpighi Hospital, Alma Mater Studiorum – University of BolognaBolognaItaly

Personalised recommendations