CIDANE: Comprehensive Isoform Discovery and Abundance Estimation

Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9029)


High-throughput sequencing of cellular RNA (RNA-seq) allows to assess the set of all RNA molecules, the transcriptome, produced by a cell at a high resolution, under various conditions. The assembly of short sequencing reads to full-length transcripts, however, poses profound challenges to bioinformatics tools.


Integer Linear Programming Abundance Estimation Result Optimization Problem Lasso Regression Regularization Path 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Center for Computational BiologyJohns Hopkins University School of MedicineBaltimoreUSA
  2. 2.Toyota Technological Institute at ChicagoChicagoUSA
  3. 3.Department of Mathematics and Computer Science, Institute of Computer ScienceFreie Universität BerlinBerlinGermany
  4. 4.Life SciencesCentrum Wiskunde & Informatica (CWI)AmsterdamThe Netherlands

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