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DockStar: A Novel ILP Based Integrative Method for Structural Modelling of Multimolecular Protein Complexes (Extended Abstract)

  • Naama Amir
  • Dan Cohen
  • Haim J. WolfsonEmail author
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9029)

Abstract

Atomic resolution modelling of large multimolecular protein complexes is a key task in Structural Cell Biology. A single cell consists of hundreds of different functional complexes.

Keywords

Span Tree Integer Linear Program Israel Science Foundation Macromolecular Assembly Multimolecular Complex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Alber, F., et al.: Determining the architectures of macromolecular assemblies. Nature 450(7170), 683–694 (2007)CrossRefGoogle Scholar
  2. 2.
    Cohen, D., et al.: 3D-Mosaic: An efficient method for integrative modeling of large multimolecular complexes (to be submitted, 2015)Google Scholar
  3. 3.
    Inbar, Y., et al.: Prediction of multimolecular assemblies by multiple docking. Journal of Molecular Biology 349(2), 435–447 (2005)CrossRefGoogle Scholar
  4. 4.
    Karaca, E., et al.: Building macromolecular assemblies by information-driven docking introducing the Haddock multibody docking server. Molecular & Cellular Proteomics 9(8), 1784–1794 (2010)CrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Blavatnik School of Computer ScienceTel Aviv UniversityTel AvivIsrael

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