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Methods for Delivering and Evaluating the Efficacy of Cognitive Enhancement

  • Chapter
Cognitive Enhancement

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 228))

Abstract

Cognitive deficits are related to impaired everyday functioning in multiple conditions and in healthy individuals. Treatment of cognitive functioning can be facilitated through either pharmacological or remediation strategies. The critical goals of cognitive enhancement are to improve everyday functioning in multiple domains. This chapter describes the strategies that are most desirable for the treatment of cognitive impairments and detection of potential benefits of treatment in cognitive and functional domains. These strategies include the use of performance-based assessments of cognition and functioning and the appropriate use of observational strategies to detect changes. Finally, we define several outcome-related goals and discuss the practicality of their measurement.

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Author information

Authors and Affiliations

  1. University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1450, Miami, FL, 33136, USA

    Philip D. Harvey

  2. Research Service, Bruce W. Carter VA Medical Center, Miami, FL, USA

    Philip D. Harvey

  3. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA

    Richard S. E. Keefe

Authors
  1. Philip D. Harvey
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  2. Richard S. E. Keefe
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Corresponding author

Correspondence to Philip D. Harvey .

Editor information

Editors and Affiliations

  1. Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA

    Kathleen M. Kantak

  2. Roche Pharmaceutical Research and Early Development; Neuroscience, Ophthalmology and Rare Diseases, F. Hoffmann-La Roche Ltd., Basel, Switzerland

    Joseph G. Wettstein

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Harvey, P.D., Keefe, R.S.E. (2015). Methods for Delivering and Evaluating the Efficacy of Cognitive Enhancement. In: Kantak, K., Wettstein, J. (eds) Cognitive Enhancement. Handbook of Experimental Pharmacology, vol 228. Springer, Cham. https://doi.org/10.1007/978-3-319-16522-6_1

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