Study of the Histogram of the Hippocampus in MRI Using the α-stable Distribution
The hippocampus is a grey matter region of the brain which is known to be affected by Alzheimer’s disease at the earliest stage. Its segmentation is important in order to measure its degree of atrophy.
We study the histogram of the intensity values of the hippocampus for 18 magnetic resonance images from the Internet Brain Segmentation Repository. In this dataset, manually-guided segmentation results are also provided. We use this database and the manual segmentation information to select the hippocampus of each of the images for the study of its histogram.
The histogram of intensity values of the left and right hippocampus for each image in the database are unimodal, heavy tailed and lightly skewed, for that reason, they can be fitted in a parsimonious way using the alpha-stable distribution. This results can be used to design a procedure to perform the segmentation of the hippocampus.
KeywordsMagnetic Resonance Image brain processing hippocampus alpha-stable distribution
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