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Balancing the Contributions of Multiple Neural Systems During Learning and Memory

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The Neurobiological Basis of Memory

Abstract

From the research era in the early 1970s that defined Ray Kesner’s and my early forays into memory research, the identification of memory attributes that depend on different neural systems has led to identification of neuroendocrine mechanisms that regulate memory processing across those systems. This chapter examines important points of convergence between investigations into multiple memory systems and memory modulation. Reviewed here is evidence showing that neurotransmitter release and energy availability within these systems participate importantly in regulating neural processing during times of learning and memory. In particular, the findings reveal neurochemical responses across neural systems while rats are engaged in different learning and memory tasks. These results thereby integrate information about the brain systems that participate in processing different attributes of memory with neurochemical regulation of the processing of different attributes of memory across neural systems.

Research described here was supported by NIA R01 AG07648, NIDA DA024129, NSF IOS 08-43175, and 13-18490, and by a grant from Alzheimer’s Association.

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Authors and Affiliations

  1. Department of Biology, Syracuse University, Life Sciences Complex 107 College Place, 13244, Syracuse, NY, USA

    Paul E. Gold PhD

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Editors and Affiliations

  1. Department of Psychology, Radford University, Radford, Virginia, USA

    Pamela A. Jackson

  2. Department of Cognitive Science, University of California-San Diego, La Jolla, California, USA

    Andrea A. Chiba

  3. Department of Neurological Surgery and Center for Neuroscience, University of California-Davis, Davis, California, USA

    Robert F. Berman

  4. Department of Psychology, University of Illinois at Chicago, Chicago, Illinois, USA

    Michael E. Ragozzino

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Gold, P. (2016). Balancing the Contributions of Multiple Neural Systems During Learning and Memory. In: Jackson, P., Chiba, A., Berman, R., Ragozzino, M. (eds) The Neurobiological Basis of Memory. Springer, Cham. https://doi.org/10.1007/978-3-319-15759-7_12

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