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Glomerular Filtration Rate in Renal Damage

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Assessment of Preclinical Organ Damage in Hypertension

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Abstract

Renal function is mainly represented by the glomerular filtration (GF), which is dependent on the number and function of the nephrons. Glomerular filtration declines progressively after the third decade with a progressive loss of 1 % per year. In addition to diseases producing direct damage in the glomerular structures, high blood pressure values, diabetes, and dyslipidemia are the main factors increasing the rate of GF decline over the years. Other functional parameters of the kidney such as renal plasma flow or tubular functions are not measured in daily practice in hypertension and are not related to risk for cardiovascular disease (CVD).

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Authors and Affiliations

  1. Hypertension Unit, Internal Medicine, Hospital Clinico, INCLIVA Research Institute, University of Valencia, Valencia, Spain

    Josep Redon, Gernot Pichler & Fernando Martinez

  2. CIBERObn, Health Institute Carlos III, Madrid, Spain

    Josep Redon

  3. Avda Blasco Ibañez, 17, 46010, Valencia, Spain

    Josep Redon

Authors
  1. Josep Redon
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  2. Gernot Pichler
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  3. Fernando Martinez
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Correspondence to Josep Redon .

Editor information

Editors and Affiliations

  1. Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

    Enrico Agabiti Rosei

  2. IRCCS Istituto Auxologico Italiano, University of Milano-Bicocca, Milano, Italy

    Giuseppe Mancia

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© 2015 Springer International Publishing Switzerland

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Redon, J., Pichler, G., Martinez, F. (2015). Glomerular Filtration Rate in Renal Damage. In: Agabiti Rosei, E., Mancia, G. (eds) Assessment of Preclinical Organ Damage in Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-319-15603-3_15

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  • DOI: https://doi.org/10.1007/978-3-319-15603-3_15

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-15602-6

  • Online ISBN: 978-3-319-15603-3

  • eBook Packages: MedicineMedicine (R0)

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