Obesity-Related Comorbidities



Obesity contributes to the development of many diseases that increase the risk of mortality and worsen the quality of life. Recent studies indicate that, relative to the normal weight category, the main contribution to excess mortality in obesity comes from higher levels of BMI, while overweight appears associated with significantly lower all-cause mortality. However, BMI does not take into account body composition and body distribution and it has been clearly established that the preferential accumulation of fat in the upper body and visceral districts is more harmful because it is associated with an increased risk of developing diabetes, dyslipidemia, and hypertension. This chapter will briefly discuss the main metabolic, cardiovascular, respiratory, psychiatric, osteoarticular, oncologic, and endocrine dysfunctions associated with obesity.


Metabolic syndrome Osteoarthritis Respiratory dysfunctions Cancer Endocrine dysfunctions 


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© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Obesity Center at the Endocrinology UnitUniversity Hospital of PisaPisaItaly

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