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Understanding and Reducing Risks via Infection in LBT Women

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Cancer and the LGBT Community

Abstract

Several infections are associated with increased risk of developing cancer. For example, persistent infection with high-risk strains of human papillomavirus causes cervical cancer. Our understanding of the association between infection and cancer in lesbian, bisexual and transgender (LBT) women is hampered by an absence of population-based data for LBT women. Formal epidemiologic studies of cancer, in general, and infection-associated cancer, in particular, among LBT individuals are lacking. This absence of robust epidemiologic data makes our understanding of infection-related cancer in the LBT women limited and speculative. This chapter attempts to summarize available epidemiologic data for infection-associated cancers in LBT women, highlight gaps in our knowledge, review interventions that have been used to reduce risk for infection-associated cancers in LBT women, and discuss challenges to research and policy that must be addressed in order prevent infection-associated cancers and reduce cancer disparities experienced by LBT women.

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References

  1. de Martel C, Ferlay J, Franceschi S, Vignat J, Bray F, Forman D, et al. Global burden of cancers attributable to infections in 2008: A review and synthetic analysis. Lancet Oncol. 2012;13(6):607–15.

    Article  PubMed  Google Scholar 

  2. Seer*Stat–incidence [Internet].www.seer.cancer.gov. Accessed 1 Feb 2014.

  3. Mosher WD, Chandra A, Jones J. Sexual behavior and selected health measures: men and women 15–44 years of age, united states, 2002. Adv Data. 2005;15(362):1–55.

    Google Scholar 

  4. Gates GJ. How many people are lesbian, gay, bisexual and transgender? UCLA: The Williams Institute; 2011.

    Google Scholar 

  5. Tracy JK, Lydecker AD, Ireland L. Barriers to cervical cancer screening among lesbians. J Womens Health (Larchmt). 2010;19(2).

    Google Scholar 

  6. Tracy JK, Schluterman NH, Greenberg DR. Understanding cervical cancer screening among lesbians: a national survey. BMC Public Health. 2013;13(1):442.

    Article  PubMed Central  PubMed  Google Scholar 

  7. Matthews AK, Brandenburg DL, Johnson TP, Hughes TL. Correlates of underutilization of gynecological cancer screening among lesbian and heterosexual women. Prev Med. 2004;38(1):105–13.

    Article  PubMed  Google Scholar 

  8. Schneider A, Koutsky LA. Natural history and epidemiological features of genital HPV infection. IARC Sci Publ. 1992;119:25–52.

    PubMed  Google Scholar 

  9. Munoz N, Castellsague X, de Gonzalez AB, Gissmann L. Chapter 1: HPV in the etiology of human cancer. Vaccine. 2006;24 Suppl 3:S3/1–10.

    Google Scholar 

  10. Centers for disease control and prevention (CDC) [Internet]. (2014). www.cdc.gov. Accessed 1 Feb 2014.

  11. Dunne EF, Unger ER, Sternberg M, McQuillan G, Swan DC, Patel SS, et al. Prevalence of HPV infection among females in the United States. JAMA. 2007;297(8):813–9.

    Article  CAS  PubMed  Google Scholar 

  12. Marrazzo JM, Koutsky LA, Stine KL, Kuypers JM, Grubert TA, Galloway DA, et al. Genital human papillomavirus infection in women who have sex with women. J Infect Dis. 1998;178(6):1604–9.

    Article  CAS  PubMed  Google Scholar 

  13. Marrazzo JM, Stine K, Koutsky LA. Genital human papillomavirus infection in women who have sex with women: a review. Am J Obstet Gynecol. 2000;183(3):770–4.

    Article  CAS  PubMed  Google Scholar 

  14. HIV-AIDS basics [Internet]. Washington, DC: US Department of Health and Human Services; (2012) [updated 6/6/2012]. http://www.aids.gov/hiv-aids-basics/. Accessed: 6 June 2012

  15. Kwakwa HA, Ghobrial MW. Female-to-female transmission of human immunodeficiency virus. Clin Infect Dis. 2003;36(3):e40–1.

    Article  PubMed  Google Scholar 

  16. Chan SK, Thornton LR, Chronister KJ, Meyer J, Wolverton M, Johnson CK, et al. Likely female-to-female sexual transmission of HIV–Texas, 2012. MMWR Morb Mortal Wkly Rep. 2014;63(10):209–12.

    PubMed  Google Scholar 

  17. Dworkin SL. Who is epidemiologically fathomable in the HIV/AIDS epidemic? Gender, sexuality, and intersectionality in public health. Cult Health Sex. 2005;7(6):615–23.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Herbst JH, Jacobs ED, Finlayson TJ, McKleroy VS, Neumann MS, Crepaz N, et al. Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review. AIDS Behav. 2008;12(1):1–17.

    Article  PubMed  Google Scholar 

  19. Baral SD, Poteat T, Stromdahl S, Wirtz AL, Guadamuz TE, Beyrer C. Worldwide burden of HIV in transgender women: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13(3):214–22.

    Article  PubMed  Google Scholar 

  20. Custer B, Sullivan SD, Hazlet TK, Iloeje U, Veenstra DL, Kowdley KV. Global epidemiology of hepatitis B virus. J Clin Gastroenterol. 2004;38(10 Suppl 3):S158–68.

    Article  PubMed  Google Scholar 

  21. Wasley A, Kruszon-Moran D, Kuhnert W, Simard EP, Finelli L, McQuillan G, et al. The prevalence of hepatitis B virus infection in the United States in the era of vaccination. J Infect Dis. 2010;202(2):192–201.

    Article  PubMed  Google Scholar 

  22. Fethers K, Marks C, Mindel A, Estcourt CS. Sexually transmitted infections and risk behaviours in women who have sex with women. Sex Transm Infect. 2000;76(5):345–9.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  23. Nuttbrock L, Hwahng S, Bockting W, Rosenblum A, Mason M, Macri M, et al. Lifetime risk factors for HIV/sexually transmitted infections among male-to-female transgender persons. J Acquir Immune Defic Syndr. 2009;52(3):417–21.

    Article  PubMed Central  PubMed  Google Scholar 

  24. Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med. 2006;144(10):705–14.

    Article  PubMed  Google Scholar 

  25. Corey L, Wald A, Celum CL, Quinn TC. The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: A review of two overlapping epidemics. J Acquir Immune Defic Syndr. 2004;35(5):435–45.

    Article  PubMed  Google Scholar 

  26. Freeman EE, Weiss HA, Glynn JR, Cross PL, Whitworth JA, Hayes RJ. Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS. 2006;20(1):73–83.

    Article  PubMed  Google Scholar 

  27. Corey L. The current trend in genital herpes. Progress in prevention. Sex Transm Dis. 1994;21(2 Suppl):S38–44.

    CAS  PubMed  Google Scholar 

  28. Ashley RL, Wald A. Genital herpes: review of the epidemic and potential use of type-specific serology. Clin Microbiol Rev. 1999;12(1):1–8.

    CAS  PubMed Central  PubMed  Google Scholar 

  29. Roberts C. Genital herpes in young adults: changing sexual behaviours, epidemiology and management. Herpes. 2005;12(1):10–4.

    PubMed  Google Scholar 

  30. Marrazzo JM, Stine K, Wald A. Prevalence and risk factors for infection with herpes simplex virus type-1 and -2 among lesbians. Sex Transm Dis. 2003;30(12):890–5.

    Article  PubMed  Google Scholar 

  31. Xu F, Sternberg MR, Markowitz LE. Women who have sex with women in the united states: Prevalence, sexual behavior and prevalence of herpes simplex virus type 2 infection-results from national health and nutrition examination survey 2001–2006. Sex Transm Dis. 2010;37(7):407–13.

    PubMed  Google Scholar 

  32. Marrazzo JM. Even NHANES evolves: some surprising findings about women who have sex with women. Sex Transm Dis. 2010;37(7):414–5.

    PubMed  Google Scholar 

  33. Rosario M, Meyer-Bahlburg HF, Hunter J, Gwadz M. Sexual risk behaviors of gay, lesbian, and bisexual youths in New York city: prevalence and correlates. AIDS Educ Prev. 1999;11(6):476–96.

    CAS  PubMed  Google Scholar 

  34. Bauer GR, Welles SL. Beyond assumptions of negligible risk: sexually transmitted diseases and women who have sex with women. Am J Public Health. 2001;91(8):1282–6.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  35. Rowen TS, Breyer BN, Lin TC, Li CS, Robertson PA, Shindel AW. Use of barrier protection for sexual activity among women who have sex with women. Int J Gynaecol Obstet. 2013;120(1):42–5.

    Article  PubMed Central  PubMed  Google Scholar 

  36. Scheer S, Peterson I, Page-Shafer K, Delgado V, Gleghorn A, Ruiz J, et al. Sexual and drug use behavior among women who have sex with both women and men: results of a population-based survey. Am J Public Health. 2002;92(7):1110–2.

    Article  PubMed Central  PubMed  Google Scholar 

  37. Bauer GR, Jairam JA, Baidoobonso SM. Sexual health, risk behaviors, and substance use in heterosexual-identified women with female sex partners: 2002 US national survey of family growth. Sex Transm Dis. 2010;37(9):531–7.

    Article  PubMed  Google Scholar 

  38. Roberts SJ, Grindel CG, Patsdaughter CA, DeMarco R, Tarmina MS. Lesbian use and abuse of alcohol: results of the Boston lesbian health project II. Subst Abus. 2004;25(4):1–9.

    Article  PubMed  Google Scholar 

  39. Drabble L, Trocki K. Alcohol consumption, alcohol-related problems, and other substance use among lesbian and bisexual women. J Lesbian Stud. 2005;9(3):19–30.

    Article  PubMed  Google Scholar 

  40. Hyde Z, Comfort J, McManus A, Brown G, Howat P. Alcohol, tobacco and illicit drug use amongst same-sex attracted women: results from the western australian lesbian and bisexual women’s health and well-being survey. BMC Public Health. 2009;9:317,2458-9-317.

    Article  Google Scholar 

  41. Chappin SR, Tross S, Sanchez JP, Dermatis H, Galanter M. Alcohol consumption patterns: gay and lesbian urban ethnic minority members. Subst Abus. 2010;31(1):71–3.

    Article  PubMed  Google Scholar 

  42. Newcomb ME, Heinz AJ, Mustanski B. Examining risk and protective factors for alcohol use in lesbian, gay, bisexual, and transgender youth: a longitudinal multilevel analysis. J Stud Alcohol Drugs. 2012;73(5):783–93.

    Article  PubMed Central  PubMed  Google Scholar 

  43. Feldman J, Bockting W. Transgender health. Minn Med. 2003;86(7):25–32.

    PubMed  Google Scholar 

  44. Nemoto T, Operario D, Keatley J, Nguyen H, Sugano E. Promoting health for transgender women: transgender resources and neighborhood space (TRANS) program in san francisco. Am J Public Health. 2005;95(3):382–4.

    Article  PubMed Central  PubMed  Google Scholar 

  45. Nemoto T, Bodeker B, Iwamoto M, Sakata M. Practices of receptive and insertive anal sex among transgender women in relation to partner types, sociocultural factors, and background variables. AIDS Care. 2014;26(4):434–40.

    Article  PubMed  Google Scholar 

  46. Advisory committee on immunization practices (ACIP) [Internet]. Atlanta, GA: Centers for Disease Control; 2014 [updated February 27, 2014]. http://www.cdc.gov/vaccines/acip/. Accessed 1 March 2014.

  47. Jemal A, Simard EP, Dorell C, Noone AM, Markowitz LE, Kohler B, et al. Annual report to the nation on the status of cancer, 1975–2009, featuring the burden and trends in human papillomavirus(HPV)-associated cancers and HPV vaccination coverage levels. J Natl Cancer Inst. 2013;105(3):175–201.

    Article  PubMed Central  PubMed  Google Scholar 

  48. Deol AK, Heath-Toby A. HIV risk for lesbians, bisexuals and other women who have sex with women. Whitepaper. Gay Men’s Health Crisis; 2009.

    Google Scholar 

  49. Kim JJ. Targeted human papillomavirus vaccination of men who have sex with men in the USA: a cost-effectiveness modelling analysis. Lancet Infect Dis. 2010;10(12):845–52.

    Article  PubMed Central  PubMed  Google Scholar 

  50. Kim JJ. Focus on research: weighing the benefits and costs of HPV vaccination of young men. N Engl J Med. 2011;364(5):393–5.

    Article  CAS  PubMed  Google Scholar 

  51. Kim JJ. Weighing the benefits and costs of HPV vaccination of young men. N Engl J Med. 2011;364(5):393–5.

    Article  CAS  PubMed  Google Scholar 

  52. Cox P, McNair R. Risk reduction as an accepted framework for safer-sex promotion among women who have sex with women. Sex Health. 2009;6(1):15–8.

    Article  PubMed  Google Scholar 

  53. Marrazzo JM. “Can I get herpes from my girlfriend?” Lesbians’ sexual health. In: Dibble SL, Robertson PA, editors. Lesbian health 101: a clinician’s guide. San Francisco: UCSF Nursing Press; 2010. p. 55–66.

    Google Scholar 

  54. Marrazzo JM, Coffey P, Bingham A. Sexual practices, risk perception and knowledge of sexually transmitted disease risk among lesbian and bisexual women. Perspect Sex Reprod Health. 2005;37(1):6–12.

    Article  PubMed Central  PubMed  Google Scholar 

  55. Bockting WO, Robinson BE, Forberg J, Scheltema K. Evaluation of a sexual health approach to reducing HIV/STD risk in the transgender community. AIDS Care. 2005;17(3):289–303.

    Article  CAS  PubMed  Google Scholar 

  56. Taylor RD, Bimbi DS, Joseph HA, Margolis AD, Parsons JT. Girlfriends: evaluation of an HIV-risk reduction intervention for adult transgender women. AIDS Educ Prev. 2011;23(5):469–78.

    Article  PubMed  Google Scholar 

  57. Wei C, Herrick A, Raymond HF, Anglemyer A, Gerbase A, Noar SM. Social marketing interventions to increase HIV/STI testing uptake among men who have sex with men and male-to-female transgender women. Cochrane Database Syst Rev. 2011;9:CD009337. doi(9):CD009337.

    PubMed  Google Scholar 

  58. McNair R. Risks and prevention of sexually transmissible infections among women who have sex with women. Sex Health. 2005;2(4):209–17.

    Article  PubMed  Google Scholar 

  59. Mercer CH, Bailey JV, Johnson AM, Erens B, Wellings K, Fenton KA, et al. Women who report having sex with women: British national probability data on prevalence, sexual behaviors, and health outcomes. Am J Public Health. 2007;97(6):1126–33.

    Article  PubMed Central  PubMed  Google Scholar 

  60. Laumann EO, Gagnon J, Michael R, Michaels S. The social organization of sexuality: sexual practices in the United States. Chicago: University of Chicago Press; 1994.

    Google Scholar 

  61. Bauer GR, Jairam JA. Are lesbians really women who have sex with women (WSW)? Methodological concerns in measuring sexual orientation in health research. Women Health. 2008;48(4):383–408.

    Article  PubMed  Google Scholar 

  62. Everett BG. Sexual orientation disparities in sexually transmitted infections: examining the intersection between sexual identity and sexual behavior. Arch Sex Behav. 2013;42(2):225–36.

    Article  PubMed Central  PubMed  Google Scholar 

  63. Brown JP, Tracy JK. Lesbians and cancer: an overlooked health disparity. Cancer Causes Control. 2008;19(10).

    Google Scholar 

  64. McNair R. Lesbian and bisexual women’s sexual health. Aust Fam Physician. 2009;38(6):388–93.

    PubMed  Google Scholar 

  65. Sell RL, Dunn PM. Inclusion of lesbian, gay, bisexual and transgender people in tobacco use-related surveillance and epidemiological research. J LGBT Health Res. 2008;4(1):27–42.

    PubMed  Google Scholar 

  66. Boehmer U, Miao X, Ozonoff A. Cancer survivorship and sexual orientation. Cancer. 2011;117(16):3796–804.

    Article  PubMed  Google Scholar 

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Correspondence to J. Kathleen Tracy .

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Tracy, J. (2015). Understanding and Reducing Risks via Infection in LBT Women. In: Boehmer, U., Elk, R. (eds) Cancer and the LGBT Community. Springer, Cham. https://doi.org/10.1007/978-3-319-15057-4_3

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