Abstract
Several infections are associated with increased risk of developing cancer. For example, persistent infection with high-risk strains of human papillomavirus causes cervical cancer. Our understanding of the association between infection and cancer in lesbian, bisexual and transgender (LBT) women is hampered by an absence of population-based data for LBT women. Formal epidemiologic studies of cancer, in general, and infection-associated cancer, in particular, among LBT individuals are lacking. This absence of robust epidemiologic data makes our understanding of infection-related cancer in the LBT women limited and speculative. This chapter attempts to summarize available epidemiologic data for infection-associated cancers in LBT women, highlight gaps in our knowledge, review interventions that have been used to reduce risk for infection-associated cancers in LBT women, and discuss challenges to research and policy that must be addressed in order prevent infection-associated cancers and reduce cancer disparities experienced by LBT women.
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References
de Martel C, Ferlay J, Franceschi S, Vignat J, Bray F, Forman D, et al. Global burden of cancers attributable to infections in 2008: A review and synthetic analysis. Lancet Oncol. 2012;13(6):607–15.
Seer*Stat–incidence [Internet].www.seer.cancer.gov. Accessed 1 Feb 2014.
Mosher WD, Chandra A, Jones J. Sexual behavior and selected health measures: men and women 15–44 years of age, united states, 2002. Adv Data. 2005;15(362):1–55.
Gates GJ. How many people are lesbian, gay, bisexual and transgender? UCLA: The Williams Institute; 2011.
Tracy JK, Lydecker AD, Ireland L. Barriers to cervical cancer screening among lesbians. J Womens Health (Larchmt). 2010;19(2).
Tracy JK, Schluterman NH, Greenberg DR. Understanding cervical cancer screening among lesbians: a national survey. BMC Public Health. 2013;13(1):442.
Matthews AK, Brandenburg DL, Johnson TP, Hughes TL. Correlates of underutilization of gynecological cancer screening among lesbian and heterosexual women. Prev Med. 2004;38(1):105–13.
Schneider A, Koutsky LA. Natural history and epidemiological features of genital HPV infection. IARC Sci Publ. 1992;119:25–52.
Munoz N, Castellsague X, de Gonzalez AB, Gissmann L. Chapter 1: HPV in the etiology of human cancer. Vaccine. 2006;24 Suppl 3:S3/1–10.
Centers for disease control and prevention (CDC) [Internet]. (2014). www.cdc.gov. Accessed 1 Feb 2014.
Dunne EF, Unger ER, Sternberg M, McQuillan G, Swan DC, Patel SS, et al. Prevalence of HPV infection among females in the United States. JAMA. 2007;297(8):813–9.
Marrazzo JM, Koutsky LA, Stine KL, Kuypers JM, Grubert TA, Galloway DA, et al. Genital human papillomavirus infection in women who have sex with women. J Infect Dis. 1998;178(6):1604–9.
Marrazzo JM, Stine K, Koutsky LA. Genital human papillomavirus infection in women who have sex with women: a review. Am J Obstet Gynecol. 2000;183(3):770–4.
HIV-AIDS basics [Internet]. Washington, DC: US Department of Health and Human Services; (2012) [updated 6/6/2012]. http://www.aids.gov/hiv-aids-basics/. Accessed: 6 June 2012
Kwakwa HA, Ghobrial MW. Female-to-female transmission of human immunodeficiency virus. Clin Infect Dis. 2003;36(3):e40–1.
Chan SK, Thornton LR, Chronister KJ, Meyer J, Wolverton M, Johnson CK, et al. Likely female-to-female sexual transmission of HIV–Texas, 2012. MMWR Morb Mortal Wkly Rep. 2014;63(10):209–12.
Dworkin SL. Who is epidemiologically fathomable in the HIV/AIDS epidemic? Gender, sexuality, and intersectionality in public health. Cult Health Sex. 2005;7(6):615–23.
Herbst JH, Jacobs ED, Finlayson TJ, McKleroy VS, Neumann MS, Crepaz N, et al. Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review. AIDS Behav. 2008;12(1):1–17.
Baral SD, Poteat T, Stromdahl S, Wirtz AL, Guadamuz TE, Beyrer C. Worldwide burden of HIV in transgender women: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13(3):214–22.
Custer B, Sullivan SD, Hazlet TK, Iloeje U, Veenstra DL, Kowdley KV. Global epidemiology of hepatitis B virus. J Clin Gastroenterol. 2004;38(10 Suppl 3):S158–68.
Wasley A, Kruszon-Moran D, Kuhnert W, Simard EP, Finelli L, McQuillan G, et al. The prevalence of hepatitis B virus infection in the United States in the era of vaccination. J Infect Dis. 2010;202(2):192–201.
Fethers K, Marks C, Mindel A, Estcourt CS. Sexually transmitted infections and risk behaviours in women who have sex with women. Sex Transm Infect. 2000;76(5):345–9.
Nuttbrock L, Hwahng S, Bockting W, Rosenblum A, Mason M, Macri M, et al. Lifetime risk factors for HIV/sexually transmitted infections among male-to-female transgender persons. J Acquir Immune Defic Syndr. 2009;52(3):417–21.
Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med. 2006;144(10):705–14.
Corey L, Wald A, Celum CL, Quinn TC. The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: A review of two overlapping epidemics. J Acquir Immune Defic Syndr. 2004;35(5):435–45.
Freeman EE, Weiss HA, Glynn JR, Cross PL, Whitworth JA, Hayes RJ. Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS. 2006;20(1):73–83.
Corey L. The current trend in genital herpes. Progress in prevention. Sex Transm Dis. 1994;21(2 Suppl):S38–44.
Ashley RL, Wald A. Genital herpes: review of the epidemic and potential use of type-specific serology. Clin Microbiol Rev. 1999;12(1):1–8.
Roberts C. Genital herpes in young adults: changing sexual behaviours, epidemiology and management. Herpes. 2005;12(1):10–4.
Marrazzo JM, Stine K, Wald A. Prevalence and risk factors for infection with herpes simplex virus type-1 and -2 among lesbians. Sex Transm Dis. 2003;30(12):890–5.
Xu F, Sternberg MR, Markowitz LE. Women who have sex with women in the united states: Prevalence, sexual behavior and prevalence of herpes simplex virus type 2 infection-results from national health and nutrition examination survey 2001–2006. Sex Transm Dis. 2010;37(7):407–13.
Marrazzo JM. Even NHANES evolves: some surprising findings about women who have sex with women. Sex Transm Dis. 2010;37(7):414–5.
Rosario M, Meyer-Bahlburg HF, Hunter J, Gwadz M. Sexual risk behaviors of gay, lesbian, and bisexual youths in New York city: prevalence and correlates. AIDS Educ Prev. 1999;11(6):476–96.
Bauer GR, Welles SL. Beyond assumptions of negligible risk: sexually transmitted diseases and women who have sex with women. Am J Public Health. 2001;91(8):1282–6.
Rowen TS, Breyer BN, Lin TC, Li CS, Robertson PA, Shindel AW. Use of barrier protection for sexual activity among women who have sex with women. Int J Gynaecol Obstet. 2013;120(1):42–5.
Scheer S, Peterson I, Page-Shafer K, Delgado V, Gleghorn A, Ruiz J, et al. Sexual and drug use behavior among women who have sex with both women and men: results of a population-based survey. Am J Public Health. 2002;92(7):1110–2.
Bauer GR, Jairam JA, Baidoobonso SM. Sexual health, risk behaviors, and substance use in heterosexual-identified women with female sex partners: 2002 US national survey of family growth. Sex Transm Dis. 2010;37(9):531–7.
Roberts SJ, Grindel CG, Patsdaughter CA, DeMarco R, Tarmina MS. Lesbian use and abuse of alcohol: results of the Boston lesbian health project II. Subst Abus. 2004;25(4):1–9.
Drabble L, Trocki K. Alcohol consumption, alcohol-related problems, and other substance use among lesbian and bisexual women. J Lesbian Stud. 2005;9(3):19–30.
Hyde Z, Comfort J, McManus A, Brown G, Howat P. Alcohol, tobacco and illicit drug use amongst same-sex attracted women: results from the western australian lesbian and bisexual women’s health and well-being survey. BMC Public Health. 2009;9:317,2458-9-317.
Chappin SR, Tross S, Sanchez JP, Dermatis H, Galanter M. Alcohol consumption patterns: gay and lesbian urban ethnic minority members. Subst Abus. 2010;31(1):71–3.
Newcomb ME, Heinz AJ, Mustanski B. Examining risk and protective factors for alcohol use in lesbian, gay, bisexual, and transgender youth: a longitudinal multilevel analysis. J Stud Alcohol Drugs. 2012;73(5):783–93.
Feldman J, Bockting W. Transgender health. Minn Med. 2003;86(7):25–32.
Nemoto T, Operario D, Keatley J, Nguyen H, Sugano E. Promoting health for transgender women: transgender resources and neighborhood space (TRANS) program in san francisco. Am J Public Health. 2005;95(3):382–4.
Nemoto T, Bodeker B, Iwamoto M, Sakata M. Practices of receptive and insertive anal sex among transgender women in relation to partner types, sociocultural factors, and background variables. AIDS Care. 2014;26(4):434–40.
Advisory committee on immunization practices (ACIP) [Internet]. Atlanta, GA: Centers for Disease Control; 2014 [updated February 27, 2014]. http://www.cdc.gov/vaccines/acip/. Accessed 1 March 2014.
Jemal A, Simard EP, Dorell C, Noone AM, Markowitz LE, Kohler B, et al. Annual report to the nation on the status of cancer, 1975–2009, featuring the burden and trends in human papillomavirus(HPV)-associated cancers and HPV vaccination coverage levels. J Natl Cancer Inst. 2013;105(3):175–201.
Deol AK, Heath-Toby A. HIV risk for lesbians, bisexuals and other women who have sex with women. Whitepaper. Gay Men’s Health Crisis; 2009.
Kim JJ. Targeted human papillomavirus vaccination of men who have sex with men in the USA: a cost-effectiveness modelling analysis. Lancet Infect Dis. 2010;10(12):845–52.
Kim JJ. Focus on research: weighing the benefits and costs of HPV vaccination of young men. N Engl J Med. 2011;364(5):393–5.
Kim JJ. Weighing the benefits and costs of HPV vaccination of young men. N Engl J Med. 2011;364(5):393–5.
Cox P, McNair R. Risk reduction as an accepted framework for safer-sex promotion among women who have sex with women. Sex Health. 2009;6(1):15–8.
Marrazzo JM. “Can I get herpes from my girlfriend?” Lesbians’ sexual health. In: Dibble SL, Robertson PA, editors. Lesbian health 101: a clinician’s guide. San Francisco: UCSF Nursing Press; 2010. p. 55–66.
Marrazzo JM, Coffey P, Bingham A. Sexual practices, risk perception and knowledge of sexually transmitted disease risk among lesbian and bisexual women. Perspect Sex Reprod Health. 2005;37(1):6–12.
Bockting WO, Robinson BE, Forberg J, Scheltema K. Evaluation of a sexual health approach to reducing HIV/STD risk in the transgender community. AIDS Care. 2005;17(3):289–303.
Taylor RD, Bimbi DS, Joseph HA, Margolis AD, Parsons JT. Girlfriends: evaluation of an HIV-risk reduction intervention for adult transgender women. AIDS Educ Prev. 2011;23(5):469–78.
Wei C, Herrick A, Raymond HF, Anglemyer A, Gerbase A, Noar SM. Social marketing interventions to increase HIV/STI testing uptake among men who have sex with men and male-to-female transgender women. Cochrane Database Syst Rev. 2011;9:CD009337. doi(9):CD009337.
McNair R. Risks and prevention of sexually transmissible infections among women who have sex with women. Sex Health. 2005;2(4):209–17.
Mercer CH, Bailey JV, Johnson AM, Erens B, Wellings K, Fenton KA, et al. Women who report having sex with women: British national probability data on prevalence, sexual behaviors, and health outcomes. Am J Public Health. 2007;97(6):1126–33.
Laumann EO, Gagnon J, Michael R, Michaels S. The social organization of sexuality: sexual practices in the United States. Chicago: University of Chicago Press; 1994.
Bauer GR, Jairam JA. Are lesbians really women who have sex with women (WSW)? Methodological concerns in measuring sexual orientation in health research. Women Health. 2008;48(4):383–408.
Everett BG. Sexual orientation disparities in sexually transmitted infections: examining the intersection between sexual identity and sexual behavior. Arch Sex Behav. 2013;42(2):225–36.
Brown JP, Tracy JK. Lesbians and cancer: an overlooked health disparity. Cancer Causes Control. 2008;19(10).
McNair R. Lesbian and bisexual women’s sexual health. Aust Fam Physician. 2009;38(6):388–93.
Sell RL, Dunn PM. Inclusion of lesbian, gay, bisexual and transgender people in tobacco use-related surveillance and epidemiological research. J LGBT Health Res. 2008;4(1):27–42.
Boehmer U, Miao X, Ozonoff A. Cancer survivorship and sexual orientation. Cancer. 2011;117(16):3796–804.
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Tracy, J. (2015). Understanding and Reducing Risks via Infection in LBT Women. In: Boehmer, U., Elk, R. (eds) Cancer and the LGBT Community. Springer, Cham. https://doi.org/10.1007/978-3-319-15057-4_3
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