Abstract
Abnormal embryonic development of the vascular system causes a variety of vascular anomalies. Vasculogenesis is genetically determined with a specific sequence of formation, selective regression, and remodeling that must occur in the correct sequence to produce the typical mature vascular system. Investigation into the genes and signaling pathways that guide this complex process are crucial to understanding how vascular anomalies develop and may ultimately provide clues for therapeutic intervention or treatment of these conditions.
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References
Patel-Hett S, D’Amore PA. Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol. 2011;55(4–5):353–63. doi:10.1387/ijdb.103213sp.
Fancher TT, Muto A, Fitzgerald TN, Magri D, Gortler D, Nishibe T, Dardik A. Control of blood vessel identity: from embryo to adult. Ann Vasc Dis. 2008;1(1):28–34. doi:10.3400/avd.AVDrev07011. Epub 2008 Feb 15.
Hong YK, Detmar M. Prox1, master regulator of the lymphatic vasculature phenotype. Cell Tissue Res. 2003;314(1):85–92. Oct. Epub 2003 Jul 22.
Schneider DJ, Moore JW. Patent ductus arteriosus. Circulation. 2006;114(17):1873–82.
Kenny D, Hijazi ZM. Coarctation of the aorta: from fetal life to adulthood. Cardiol J. 2011;18(5):487–95.
Cinà CS, Althani H, Pasenau J, Abouzahr L. Kommerell’s diverticulum and right-sided aortic arch: a cohort study and review of the literature. J Vasc Surg. 2004;39(1):131–9.
Ciervo A, Kahn M, Pangilinan AJ, Dardik H. Absence of the brachial artery: report of a rare human variation and review of upper extremity arterial anomalies. J Vasc Surg. 2001;33(1):191–4.
van Hooft IM, Zeebregts CJ, van Sterkenburg SM, de Vries WR, Reijnen MM. The persistent sciatic artery. Eur J Vasc Endovasc Surg. 2009;37(5):585–91.
Pillai J. A current interpretation of popliteal vascular entrapment. J Vasc Surg. 2008;48(6 Suppl):61S–5; discussion 65S.
Spentzouris G, Zandian A, Cesmebasi A, Kinsella CR, Muhleman M, Mirzayan N, Shirak M, Tubbs RS, Shaffer K, Loukas M. The clinical anatomy of the inferior vena cava: a review of common congenital anomalies and considerations for clinicians. Clin Anat. 2014;27(8):1234–43.
Natsis K, Tsitouridis I, Totlis T, Levva S, Tsikaras P, Skandalakis P. Proposal for classification of the circumaortic renal collar’s morphology. Am Surg. 2008;74(12):1190–4.
Uhl JF, Gillot C, Chahim M. Anatomical variations of the femoral vein. J Vasc Surg. 2010;52(3):714–9.
Vural E, Ramakrishnan J, Cetin N, et al. The expression of vascular endothelial growth factor and its receptors in port-wine stains. Otolaryngol Head Neck Surg. 2008;139:560.
Shirley MD, Tang H, Gallione CJ, et al. Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ. N Engl J Med. 2013;368:1971.
Gloviczki P, Driscoll DJ. Klippel-Trenaunay syndrome: current management. Phlebology. 2007;22(6):291–8.
Jacob AG, Driscoll DJ, Shaughnessy WJ, et al. Klippel-Trénaunay syndrome: spectrum and management. Mayo Clin Proc. 1998;73:28.
Koltowska K, Betterman KL, Harvey NL, Hogan BM. Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature. Development. 2013;140(9):1857–70.
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Foster, T.R., Chin, J.A., Brownson, K.E., Bai, H., Dardik, A. (2016). Embryological Basis for Vascular Anomalies. In: Bhattacharya, N., Stubblefield, P. (eds) Human Fetal Growth and Development. Springer, Cham. https://doi.org/10.1007/978-3-319-14874-8_27
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DOI: https://doi.org/10.1007/978-3-319-14874-8_27
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