Skip to main content

Borreliosis

  • Chapter
  • First Online:
  • 1867 Accesses

Abstract

Bacteria of the genus Borrelia are responsible for causing numerous diseases that can affect humans and also animals. Among these diseases we have Lyme disease and relapsing fever. Lyme disease, whose etiological agents are bacteria of the Borrelia burgdorferi s.l., is considered a major emerging zoonosis, especially in the northern hemisphere. Very important in the past, but now with a reduced number of accounts, due to a decrease in its vector, the louse, relapsing fever is caused by at least 15 different Borrelia species. Several other borreliosis affect animals and deserve significant attention. Avian and bovine borreliosis can be cited as examples of these. Currently, the main method of control and prophylaxis of these diseases is the control of their vectors, since there are no vaccines for them. Epidemiological studies are also of great value for the control of borreliosis, since they allow monitoring the endemic areas for these ills.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Notes

  1. 1.

    See Chap. 3 for more information on the history of Lyme disease (CBM).

  2. 2.

    See Chap. 34 for more information on paralysis caused by ticks (CBM).

References

  • Barbour AG (1984) Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med 57(4):521–525

    CAS  PubMed  PubMed Central  Google Scholar 

  • Barbour AG, Maupin GO, Teltow GJ et al (1996) Identification of an uncultivable Borrelia species in the hard tick Amblyomma americanum: possible agent of a Lyme disease-like illness. J Infect Dis 173:403–409

    Article  CAS  PubMed  Google Scholar 

  • Berger BW (1989) Dermatologic manifestations of Lyme disease. Rev Infect Dis 11:S1475

    Article  PubMed  Google Scholar 

  • Berger BW, Kaplan MH, Rothenberg IR, Barbour AG (1985) Isolation and characterization of Lyme disease spirochete from the skin of patients with erythema chronicum migrans. J Am Acad Dermatol 13:444–449

    Article  CAS  PubMed  Google Scholar 

  • Burgdorfer W, Barbour AG, Hayes SF et al (1982) Lyme disease-a tick-borne spirochetosis? Science 216:1317–1319

    Article  CAS  PubMed  Google Scholar 

  • Burgdorfer W, Barbour AG, Hayes SF et al (1983) Erythema chronicum migrans: a tick borne spirochetosis. Acta Trop 40:79–83

    CAS  PubMed  Google Scholar 

  • Burgdorfer W, Lane RS, Barbour AG et al (1985) The western black-legged tick, Ixodes pacificus: a vector of Borrelia burgdorferi. Am J Trop Med Hyg 34:925–930

    Google Scholar 

  • Cavalier-Smith T (2002) The neomuran origin of archaebacteria, the negibacterial root of the universal tree and bacterial megaclassification. Int J Syst Evol Microbiol 52:7–76

    Article  CAS  PubMed  Google Scholar 

  • Ciceroni L, Bartoloni A, Guglielmetti P et al (1994) Prevalence of antibodies to Borrelia burgdorferi, Borrelia parkeri and Borrelia turicatae in human settlements of the Cordillera Province, Bolivia. J Trop Med Hyg 97:13–17

    CAS  PubMed  Google Scholar 

  • Clark KL, Leydet BF, Threlkeld C (2014) Geographical and genospecies distribution of Borrelia burgdorferi sensu lato DNA detected in humans in the USA. J Med Microbiol 63:674–684

    Article  CAS  PubMed  Google Scholar 

  • Costa IP, Yoshinari NH, Barros PJL et al (1996) Doença de Lyme em Mato Grosso do Sul: relato de três casos clínicos, incluindo o primeiro relato de meningite de Lyme no Brasil. Rev Hosp Clín Fac Med Sao Paulo 51:253–257

    CAS  PubMed  Google Scholar 

  • Costa IP, Bonoldi VL, Yoshinari NH (2002) Search for Borrelia sp. in ticks collected from potential reservoirs in an urban forest reserve in the State of Mato Grosso do Sul, Brazil: a short report. Mem Inst Oswaldo Cruz 97:631–635

    Article  PubMed  Google Scholar 

  • Cutler SJ (2009) Relapsing fever—a forgotten disease revealed. J Appl Microbiol 108:1115–1122

    Article  PubMed  Google Scholar 

  • Dunaj J, Moniuszko A, Zajkowska J et al (2013) The role of PCR in diagnostics of Lyme borreliosis. Przegl Epidemiol 67:35–39

    PubMed  Google Scholar 

  • El-Bahnsawy MM, Labib NA, Abdel-Fattah MA et al (2012) Louse and tick borne relapsing fevers. J Egypt Soc Parasitol 42:625–638

    PubMed  Google Scholar 

  • Flach AJ, Lavoie PE (1990) Episcleritis, conjunctivitis, and keratitis as ocular manifestations of Lyme disease. Ophthalmology 97:973–975

    Article  CAS  PubMed  Google Scholar 

  • Fonseca AH, Salles RS, Salles SAN et al (2005) Borreliose de Lyme simile: uma doença emergente e relevante para a dermatologia no Brasil. An Bras Dermatol 80:171–178

    Article  Google Scholar 

  • Fraser CM, Casjens S, Huang WM et al (1997) Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390:580–586

    Google Scholar 

  • Hall MR, Hanks D, Kvasnicka W et al (2002) Diagnosis of epizootic bovine abortion in Nevada and identification of the vector. J Vet Diagn Invest 14:205–210

    Article  PubMed  Google Scholar 

  • Halperin JJ (1997) Neuroborreliosis: central nervous system involvement. Semin Neurol 17:19–24

    Article  CAS  PubMed  Google Scholar 

  • Hampson DJ, Swayne DE (2013) Avian intestinal spirochetosis. In: Saif YM (ed) Diseases of poultry, 13th edn. Wiley, New York, pp 922–940

    Google Scholar 

  • Hoogstraal H (1985) Argasid and nuttalliellid ticks as parasites and vectors. Adv Parasitol 24:135–238

    Article  CAS  PubMed  Google Scholar 

  • Hossain H, Wellensiek HJ, Geyer R et al (2001) Structural analysis of glycolipids from Borrelia burgdorferi. Biochimie 83:683–692

    Article  CAS  PubMed  Google Scholar 

  • Koning J, Hoogkamp-Korstanje JA (1986) Diagnosis of Lyme disease by demonstration of spirochetes in tissue biopsies. Zbl Bakt Hyg A 263:179–188

    Google Scholar 

  • Lee SH, Vigliotti VS, Vigliotti JS et al (2010) Increased sensitivity and specificity of Borrelia burgdorferi 16S ribosomal DNA detection. Am J Clin Pathol 133:569–576

    Article  CAS  PubMed  Google Scholar 

  • Lemos ER, Alvarenga FB, Cintra ML et al (2001) Spotted fever in Brazil: a seroepidemiological study and description of clinical cases in an endemic area in the state of São Paulo. Am J Trop Med Hyg 65:329–334

    PubMed  Google Scholar 

  • MacDonald AB (2006) Plaques of Alzheimer's disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete. Med Hypothesis 67:592–600

    Article  CAS  Google Scholar 

  • Magnarelli LA, Anderson JF, Schreier AB et al (1987) Clinical and serologic studies of canine borreliosis. J Am Vet Med Assoc 191:1089–1094

    CAS  PubMed  Google Scholar 

  • Malane MS, Grant-Kels JM, Feder H et al (1991) Diagnosis of Lyme disease based on dermatologic manifestations. Ann Intern Med 114:490–498

    Article  CAS  PubMed  Google Scholar 

  • McCoy BN, Maïga O, Schwan TG (2014) Detection of Borrelia theileri in Rhipicephalus geigyi from Mali. Ticks Tick Borne Dis 5:401–403

    Article  PubMed  PubMed Central  Google Scholar 

  • Montandon CE, Yoshinari NH, Milagres BS et al (2014) Evidence of Borrelia in wild and domestic mammals from the state of Minas Gerais, Brazil. Rev Bras Parasitol Vet 23:287–290

    Article  PubMed  Google Scholar 

  • Nadelman RB, Nowakowski J, Fish D et al (2001) Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite. N Engl J Med 345:79–84

    Article  CAS  PubMed  Google Scholar 

  • Nadelman RB, Hanincová K, Mukherjee P et al (2012) Differentiation of reinfection from relapse in recurrent Lyme disease. N Engl J Med 367:1883–1890

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Piesman J, Mather TN, Sinsky RJ et al (1987) Duration of tick attachment and Borrelia burgdorferi transmission. J Clin Microbiol 25:557–558

    CAS  PubMed  PubMed Central  Google Scholar 

  • Rogers AB, Smith RD, Kakoma I (1999) Serologic cross-reactivity of antibodies against Borrelia theileri, Borrelia burgdorferi, and Borrelia coriaceae in cattle. Am J Vet Res 60:694–697

    Google Scholar 

  • Saif YM (ed) (2013) Diseases of poultry, 13th edn. Wiley, New York

    Google Scholar 

  • Shapiro ED (2015) Repeat or persistent Lyme disease: persistence, recrudescence or reinfection with Borrelia burgdorferi? F1000 Prime Rep 7:11

    Article  Google Scholar 

  • Shapiro ED, Gerber MA, Holabird NB et al (1992) A controlled trial of antimicrobial prophylaxis for Lyme disease after deer-tick bites. N Engl J Med 327:1769–1773

    Article  CAS  PubMed  Google Scholar 

  • Silva AM, Fikrig E (1997) Borrelia burgdorferi genes selectively expressed in ticks and mammals. Parasitol Today 13:267–270

    Article  PubMed  Google Scholar 

  • Smith RD, Brener J, Osorno M, Ristic M (1978) Pathobiology of Borrelia theileri in the tropical cattle tick, Boophilus microplus. J Invertebr Pathol 32:182–190

    Article  CAS  PubMed  Google Scholar 

  • Stanchi NO, Balague LJ (1993) Lyme disease: antibodies against Borrelia burgdorferi in farm workers in Argentina. Rev Saúde Públ 27:305–307

    Article  CAS  Google Scholar 

  • Steere AC, Coburn J, Glickstein L (2004) The emergence of Lyme disease. J Clin Invest 113:1093–1101

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Steere AC, Grodzicki RI, Kornblatt AN et al (1983) The spirochetal etiology of Lyme disease. New Engl J Med 308:733–740

    Google Scholar 

  • Steere AC, Mchugh G, Damle N, Sikand VK (2008) Prospective study of serologic tests for Lyme disease. Clin Infect Dis 47:188–195

    Article  PubMed  Google Scholar 

  • Teglas MB, Mapes S, Hodzic E et al (2011) Co-infection of Ornithodoros coriaceus with the relapsing fever spirochete, Borrelia coriaceae, and the agent of epizootic bovine abortion. Med Vet Entomol 25:337–343

    Article  CAS  PubMed  Google Scholar 

  • Yoshinari NH (2009) Uma longa jornada para entender a Borrelia burgdorferi no Brasil. Rev Bras Reumatol 49:483–486

    Google Scholar 

  • Yoshinari NH, Oyafuso LK, Monteiro FGV et al (1993) Doença de Lyme. Relato de um caso observado no Brasil. Rev Hosp Clín Fac Med Sao Paulo 48:170–174

    CAS  PubMed  Google Scholar 

  • Yoshinari NH, Barros PJL, Gauditano G et al (2000) Report of 57 cases of Lyme-like disease (LLD) in Brazil. Arthritis Rheum 43:S188

    Google Scholar 

  • Yoshinari NH, Abrão MG, Bonoldi VL et al (2003) Coexistence of antibodies to tick—borne agents of babesiosis and Lyme borreliosis in patients from Cotia county, State of São Paulo, Brazil. Mem Inst Oswaldo Cruz 98:311–318

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Cláudio Mafra .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Mafra, C., Montandon, C.E. (2017). Borreliosis. In: Marcondes, C. (eds) Arthropod Borne Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-13884-8_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-13884-8_13

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13883-1

  • Online ISBN: 978-3-319-13884-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics