Advertisement

Ureteropyeloscopic Treatment of Upper Urinary Tract Urothelial Malignancy

Chapter
  • 433 Downloads

Abstract

The treatment of upper urinary tract urothelial malignancy has paralleled similar therapies in the lower urinary tract. The majority of bladder tumors that are superficial, non-invasive, and low grade in histology are treated endoscopically, not with extirpative surgery. Prohibitive factors historically with regard to treating upper tract lesions endoscopically have been the large size and poor directability of the original ureteroscopes and the limited efficacy and availability of energy sources to treat these lesions. This has evolved as endoscopic instrumentation has improved. Endoscope miniaturization with improved mechanics have allowed for complete inspection of the entire upper urinary tract, and the application of various wavelengths of laser light energy employed to both coagulate and resect upper tract urothelial tumors have remarkably changed how these lesions are treated.

Keywords

Lower Urinary Tract High Grade Lesion Extirpative Surgery Intramural Segment Ureteroscopic Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Huffman JL, Bagley DH, Lyon ES, et al. Endoscopic diagnosis and treatment of upper-tract urothelial tumors: a preliminary report. Cancer. 1985;55:1422–8.PubMedCrossRefGoogle Scholar
  2. 2.
    Johnson GB, Portela D, Grasso M. Advanced ureteroscopy: wireless and sheathless. J Endourol. 2006;20(8):552–5.PubMedCrossRefGoogle Scholar
  3. 3.
    Grasso M, Fraiman M, Levine M. Ureteropyeloscopic diagnosis and treatment of upper urinary tract urothelial malignancies. Urology. 1999;54(2):240–6.PubMedCrossRefGoogle Scholar
  4. 4.
    Grasso M, Bagley DH. A 7.5/8.2 French actively deflectable, flexible ureteroscope: a new device for both diagnostic and therapeutic upper urinary tract endoscopy. Urology. 1994;43:435–41.PubMedCrossRefGoogle Scholar
  5. 5.
    Johnson GB, Grasso M. Exaggerated primary endoscope deflection: initial clinical experience with prototypic flexible ureteroscopes: the first 115 procedures. BJU. 2003;93(1):109–14.CrossRefGoogle Scholar
  6. 6.
    Bagley DH, Kulp DA, Bibbo M. Ureteroscopic biopsy optimized by cytopathologic techniques. J Urol. 1994;151:387A.Google Scholar
  7. 7.
    Abdel-Razzak OM, Ehya H, Cubler-Goodman A, Bagley DH. Ureteroscopic biopsy in the upper urinary tract. Urology. 1994;44:451–7.PubMedCrossRefGoogle Scholar
  8. 8.
    Keeley FX, Kulp DA, Bibbo M, et al. Diagnostic accuracy of ureteroscopic biopsy in upper tract transitional cell carcinoma. J Urol. 1997;157:33–7.PubMedCrossRefGoogle Scholar
  9. 9.
    Cutress ML, Stewart GD, Wells-Cole S, Phipps S, Thomas BG, Tolley DA. Long-term endoscopic management of upper tract urothelial carcinoma: 20-year single-centre experience. BJU Int. 2012;110(11):1608–17.PubMedCrossRefGoogle Scholar
  10. 10.
    Daneshmand S, Quek ML, Huffman JL. Endoscopic management of upper urinary tract transitional cell carcinoma: long-term experience. Cancer. 2003;98:55–60.PubMedCrossRefGoogle Scholar
  11. 11.
    Keeley Jr FX, Bibbo M, Bagley DH. Ureteroscopic treatment and surveillance of upper urinary tract transitional cell carcinoma. J Urol. 1997;157(5):1560–5.PubMedCrossRefGoogle Scholar
  12. 12.
    Canfield SE, Dinney CP, Droller MJ. Surveillance and management of recurrence for upper tract transitional cell carcinoma. Urol Clin North Am. 2003;30(4):791–802.PubMedCrossRefGoogle Scholar
  13. 13.
    Johnson G, Fraiman M, Grasso M. Broadening experience with the retrograde endoscopic management of upper urinary tract urothelial malignancies. BJU Int. 2005;95 Suppl 2:110–3.PubMedCrossRefGoogle Scholar
  14. 14.
    Johnson GB, Grasso M. Ureteroscopic management of upper urinary tract transitional cell carcinoma. Curr Opin Urol. 2005;15(2):89–93.PubMedCrossRefGoogle Scholar
  15. 15.
    Bagley DH, Grasso M. Ureteroscopic laser treatment of upper urinary tract neoplasms. World J Urol. 2010;28:143–9.PubMedCrossRefGoogle Scholar
  16. 16.
    Schmeller NT, Hofstetter AG. Laser treatment of ureteral tumors. J Urol. 1989;141:840–3.PubMedGoogle Scholar
  17. 17.
    Floratos DL, de la Rosette JJ. Lasers in urology. BJU Int. 1999;84(2):204–11.PubMedCrossRefGoogle Scholar
  18. 18.
    von Eschenbach A. Chapter 6: Superficial bladder cancer. In: Smith JA (editors) Lasers in urologic surgery. Yearbook Medical Publishing; 1989. The University of Michigan. p 57–66.Google Scholar
  19. 19.
    Ali Ansari M, Mohajerani E. Mechanisms of laser-tissue interaction: optical properties of tissue. J Lasers Med Sci. 2011;2(3):119–25.Google Scholar
  20. 20.
    Nargund VH, Tanabalan CK, Kabir MN. Management of non-muscle-invasive (superficial) bladder cancer. Semin Oncol. 2012;39(5):559–72.PubMedCrossRefGoogle Scholar
  21. 21.
    Martinez-Pineiro JA, Garcia Matres MJ, Martinez-Pineiro L. Endourological treatment of upper tract urothelial carcinomas: analysis of a series of 59 tumors. J Urol. 1996;156(2 Pt 1):377–85.PubMedCrossRefGoogle Scholar
  22. 22.
    Keeley Jr FX, Bagley DH. Adjuvant mitomycin C following endoscopic treatment of upper tract transitional cell carcinoma. J Urol. 1997;158(6):2074–7.PubMedCrossRefGoogle Scholar
  23. 23.
    Aboumarzouk OM, Somani B, Ahmad S, Nabi G, Townell N, Kata SG. Mitomycin C instillation following ureterorenoscopic laser ablation of upper urinary tract carcinoma. Urol Ann. 2013;5(3):184–9.PubMedCentralPubMedCrossRefGoogle Scholar
  24. 24.
    Audenet F, Traxer O, Bensalah K, Rouprêt M. Upper urinary tract instillations in the treatment of urothelial carcinomas: a review of technical constraints and outcomes. World J Urol. 2013;31(1):45–52.PubMedCrossRefGoogle Scholar
  25. 25.
    Cutress ML, Stewart GD, Zakikhani P, Phipps S, Thomas BG, Tolley DA. Ureteroscopic and percutaneous management of upper tract urothelial carcinoma (UTUC): systematic review. BJU Int. 2012;110(5):614–28.PubMedCrossRefGoogle Scholar
  26. 26.
    Chew BH, Pautler SE, Denstedt JD. Percutaneous management of upper-tract transitional cell carcinoma. J Endourol. 2005;19(6):658–63.PubMedCrossRefGoogle Scholar
  27. 27.
    Irwin BH, Berger AK, Brandina R, Stein R, Desai MM. Complex percutaneous resections for upper-tract urothelial carcinoma. J Endourol. 2010;24(3):367–70.PubMedCrossRefGoogle Scholar
  28. 28.
    Rouprêt M, Traxer O, Tligui M, et al. Upper urinary tract transitional cell carcinoma: recurrence rate after percutaneous endoscopic resection. Eur Urol. 2007;51(3):709–14.PubMedCrossRefGoogle Scholar
  29. 29.
    Grasso M, Fishman AI, Cohen J, Alexander B. Ureteroscopic and extirpative treatment of upper urinary tract urothelial carcinoma: a 15-year comprehensive review of 160 consecutive patients. BJU Int. 2012;110(11):1618–26.PubMedCrossRefGoogle Scholar
  30. 30.
    van der Heijden AG, Witjes JA. Recurrence, progression, and follow-up in non–muscle-invasive bladder cancer. Eur Urol. 2009;8(Suppl):556–62.CrossRefGoogle Scholar
  31. 31.
    Berger A, Haber GP, Kamoi K, et al. Laparoscopic radical nephroureterectomy for upper tract transitional cell carcinoma: oncological outcomes at 7 years. J Urol. 2008;180:849–54.PubMedCrossRefGoogle Scholar
  32. 32.
    Elliott DS, Blute ML, Patterson DE, Bergstralh EJ, Segura JW. Long-term follow-up of endoscopically treated upper urinary tract transitional cell carcinoma. Urology. 1996;47(6):819–25.PubMedCrossRefGoogle Scholar
  33. 33.
    Martínez-Piñeiro JA, García Matres MJ, Martínez-Piñeiro L. Endourological treatment of upper tract urothelial carcinomas: analysis of a series of 59 tumors. J Urol. 1996;156(2 Pt 1):377–85.PubMedCrossRefGoogle Scholar
  34. 34.
    Leow JJ, Martin-Doyle W, Fay AP, Choueiri TK, Chang SL, Bellmunt J. A systematic review and meta-analysis of adjuvant and neoadjuvant chemotherapy for upper tract urothelial carcinoma. Eur Urol. 2014;66(3):529–41.PubMedCrossRefGoogle Scholar
  35. 35.
    Grossman HB, Natale RB, Tangen CM, Speights VO, et al. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med. 2003;349(9):859–66.PubMedCrossRefGoogle Scholar
  36. 36.
    Porten S, Siefker-Radtke AO, Xiao L, et al. Neoadjuvant chemotherapy improves survival of patients with upper tract urothelial carcinoma. Cancer. 2014;120(12):1794–9.PubMedCentralPubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Department of UrologyNew York Medical CollegeValhallaUSA
  2. 2.Department of UrologyLenox Hill HospitalNew YorkUSA
  3. 3.Department of UrologyLenox Hill HospitalNew YorkUSA
  4. 4.Department of UrologyNew York Medical CollegeValhallaUSA

Personalised recommendations