Skip to main content

Physical and Occupational Therapy

  • Chapter
  • First Online:
  • 1742 Accesses

Abstract

Those undergoing hematopoietic stem cell transplant and related treatment are at risk for significant deconditioning and loss of overall functional abilities. The use of physical activity, in the form of both aerobic and strengthening, has been shown to be effective in the prevention and remediation of loss of strength, cancer-related fatigue, loss of cognitive functioning, and decreased quality of life. Rehabilitation services, primarily occupational and physical therapies, are beneficial members of the treatment team and are able to assist with return of function using a variety of techniques including engagement in physical activity.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • AOTA State Affairs Group. Model occupational therapy practice act. Bethesda; 2007.

    Google Scholar 

  • Barsevik A. Energy conservation and cancer-related fatigue. Rehabil Oncol. 2002;20:14–8.

    Google Scholar 

  • Carlson L, Smith D, Russell J, Fibich C, Whittaker T. Individualized exercise program for the treatment of severe fatigue in patients after allogeneic hematopoietic stem-cell transplant: a pilot study. Bone Marrow Transplant. 2006;37:945–54.

    Article  CAS  PubMed  Google Scholar 

  • Chiffelle R, Kenny K. Exercise for fatigue management in hematopoietic stem cell transplantation recipients. Clin J Oncol Nurs. 2013;17:241–4.

    Article  PubMed  Google Scholar 

  • Cooper J. Occupational therapy approach in symptom control. In: Cooper J, editor. Occupational therapy in oncology and palliative care. 2nd edn. Chichester: Wiley; 2006. p. 27–39.

    Google Scholar 

  • Courneya K, Keats M, Turner A. Physical exercise and quality of life in cancer patients following high dose chemotherapy and autologous bone marrow transplantation. Psychooncology. 2000;9:127–36.

    Article  CAS  PubMed  Google Scholar 

  • Danaher Hacker E, Ferrans C, Verlen E, Ravandi F, van Besien K, Gelms J, et al. Fatigue and physical activity in patients undergoing hematopoietic stem cell transplant. Oncol Nurs Forum. 2006;33:614–24.

    Article  Google Scholar 

  • Dimeo F, Stieglitz R, Novelli-Fischer U, Fetscher S, Keul J. Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer. 1999;85:2273–7.

    Article  CAS  PubMed  Google Scholar 

  • Dimeo R, Schwartz S, Wesel N, Voigt A, Thiel E. Effects of an endurance and resistance exercise program on persistent cancer-related fatigue after treatment. Ann Oncol. 2008;19:1495–9.

    Article  CAS  PubMed  Google Scholar 

  • Elter T, Stipanov M, Heuser E, von Bergwelt-Baildon M, Bloch W, Hallek M, et al. Is physical exercise possible in patients with critical cytopenia undergoing intensive chemotherapy for acute leukaemia or aggressive lymphoma? Int J Hematol. 2009;90:199–204.

    Article  CAS  PubMed  Google Scholar 

  • Gillis T, Donovan E. Rehabilitation following bone marrow transplantation. Cancer. 2001;92:998–1007.

    Article  CAS  PubMed  Google Scholar 

  • Hacker E, Larson J, Peace D. Exercise in patients receiving hematopoietic stem cell transplantation: lessons learned and results from a feasibilty study. Oncol Nurs Forum. 2011a;38:216–23.

    Article  PubMed Central  PubMed  Google Scholar 

  • Hacker E, Larson J, Kujath A, Peace D, Rondelli D, Gaston L. Strength training following hematopoietic stem cell transplantation. Cancer Nurs. 2011b;34:238–49.

    Article  PubMed Central  PubMed  Google Scholar 

  • Hayes S, PS D, Parker T, Bashford J, Green A. The role of a mixed type, moderate intensity, exercise program following peripheral blood stem cell transplantation. Br J Sports Med. 2004;38:304–9.

    Article  PubMed Central  PubMed  Google Scholar 

  • James M. Physical therapy for patients after bone marrow transplantation. Phys Ther. 1987;67:946–52.

    CAS  PubMed  Google Scholar 

  • Jarden M, Hovgaard D, Boesen E, Quist M, Adamsen L. Pilot study of a multimodal intervention: mixed-type exercise and psychoeducation in patients undergoing allogeneic stem cell transplantation. Bone Marrow Transplant. 2007;40:793–800.

    Article  CAS  PubMed  Google Scholar 

  • Jarden M, Baadsgaard M, Hovgaard D, Boessen E, Adamsen L. A randomized trial on the effect of a multimodal intervention on physical capacity, functional performance and quality of life in adults undergoing allogenic SCT. Bone Marrow Transplant. 2009;43:725–37.

    Article  CAS  PubMed  Google Scholar 

  • Jobst E. Physical therapy case files: acute care. New York: McGraw Hill Education; 2013.

    Google Scholar 

  • Knols R, de Bruin E, Uebelhart D, Aufdemkampe G, Schanz U, Stenner-Liewen F, et al. Effects of an outpatient physical exercise program on hematopoietic stem-cell transplantation recipients: a randomized control trial. Bone Marrow Transplant. 2001;46:1245–55.

    Article  Google Scholar 

  • Lee J, Moinzadeh L. Organ transplantation. In: Paz J, West M, editors. Acute care handbook for physical therapists. St. Louis: Saunders Elsevier; 2009. p. 419–21.

    Google Scholar 

  • Lee S, Joffe S, Haesook T, Socie G, Gilman A, Wingard J, et al. Physicians’ attitudes about quality of life issues in hematopoietic stem cell transplantation. Blood. 2004;104:2194–200.

    Article  CAS  PubMed  Google Scholar 

  • Longpre’ S, Newman R. The role of occupational therapy in oncology. Bethesda: American Occupational Therapy Association; 2011.

    Google Scholar 

  • Lowrie D. Occupational therapy and cancer-related fatigue. In: Cooper J, editor. Occupational therapy in oncology and palliative care. 2nd edn. Chicester: Wiley; 2006. p. 61–81.

    Google Scholar 

  • Mock V. Evidenced-based treatment for cancer-related fatigue. J Natl Cancer Inst Monogr. 2004;32:112–8.

    Article  PubMed  Google Scholar 

  • Nakago K, Senda M, Touno M, Takahara Y, Inoue H. Influence of exercise on muscle fibers in rats with steroid myopathy. Acta Med Okayama. 1999;53:265–70.

    CAS  PubMed  Google Scholar 

  • NCCN. NCCN clinical practice guidelines in oncology: cancer-related fatigue. National Comprehensive Cancer Network. 2013. http://www.nccn.org/professionals/physician_gls/pdf/fatigue.pdf. Accessed 17 Sept 2013.

  • Okita M, Yoshimura T, Nakano J, Watabe M, Nagai T, Kato K, et al. Effects of treadmill exercise on muscle fibers in mice with steroid myopathy. Jpn Phys Ther Assoc. 2001;4:25–7.

    Article  CAS  Google Scholar 

  • Paul K. Rehabilitation and exercise considerations in hematologic malignancies. Am J Phys Med Rehabil. 2011;90:S76–82.

    Article  PubMed  Google Scholar 

  • Penfold S. The role of the occupational therapist in oncology. Cancer Treat Rev. 1996;22:75–81.

    Article  CAS  PubMed  Google Scholar 

  • Rogge H. Sport in oncological patients. Physiotherapie. 1989;80:540–2.

    Google Scholar 

  • Rosipal N, Mingle L, Smith J, Morris G. Assessment of voluntary exercise behavior and active video gaming among adolescent and young adult patients during hematopoietc stem cell transplantation. J Pediatr Oncol Nurs. 2012;30:24–33.

    Article  PubMed  Google Scholar 

  • van Weert E, Hoekstra-Weebers J, May A, Korstjens I, Ros W, van der Schans C. The development of an evidenced-based physical self-management rehabilitation programme for cancer survivors. Patient Educ Couns. 2008;71:169–90.

    Article  PubMed  Google Scholar 

  • Wilson R, Jacobsen P, Fields K. Pilot study of a home-based aerobic exercise program for sedentary cancer survivors treated with hematopoietic stem cell transplantation. Bone Marrow Transplant. 2005;35:721–7.

    Article  CAS  PubMed  Google Scholar 

  • Winningham M, MacVicar M, Burke C. Exercise for cancer patients. Guidelines and precautions. Phys Sports Med. 1986;14:125–34.

    Google Scholar 

  • Wiskemann J, Huber G. Physical exercise as adjuvant therapy for patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant. 2008;41:321–9.

    Article  CAS  PubMed  Google Scholar 

  • Wiskemann J, Dreger P, Schwerdtfeger R, Bongdong A, Huber G, Kleindienst N, et al. Effects of a partly self-administered exercise program before, during, and after allogeneic stem cell transplantation. Blood. 2011;117:2604–13.

    Article  CAS  PubMed  Google Scholar 

  • Wolin K, Schwartz A, Matthews C, Courneya K, Schmitz K. Implementing the exercise guidelines for cancer survivors. J Support Oncol. 2012;10:171–7.

    Article  PubMed Central  PubMed  Google Scholar 

  • World Confederation for Physical Therapy. World Confederation for Physical Therapy. 2013. http://www.wcpt.org/policy/ps-descriptionPT. Accessed 24 Aug 2013.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jennifer Pidkowicz BSKine, MSOT, OTR/L .

Editor information

Editors and Affiliations

Conclusion

Conclusion

The side effects associated with high-dose chemotherapy and HSCT may result in physical debilitation. The incorporation of physical activity has been shown to minimize the loss of strength, independence, energy, and quality of life. Although the majority of research has been performed on limited sample sizes, it can be inferred by the multitude of studies across the spectrum of cancer diagnoses that physical activity is likely to be beneficial for the HSCT population.

An optimal exercise program has not been defined; however, it has been shown that moderate aerobic activity along with a strengthening routine may help prevent steroid myopathy and improve cancer-related fatigue quality of life.

Occupational and physical therapists are essential members of the HSCT treatment team who provide recommendations on the implementation of physical activity, as well as assist with prevention, remediation, and compensation of the complications associated with treatment.

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Pidkowicz, J. (2015). Physical and Occupational Therapy. In: Maziarz, R., Slater, S. (eds) Blood and Marrow Transplant Handbook. Springer, Cham. https://doi.org/10.1007/978-3-319-13832-9_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-13832-9_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-13831-2

  • Online ISBN: 978-3-319-13832-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics