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This chapter systematically reviews the literature on business incubators and business incubation. Focusing on the primary research orientations—i.e. studies centering on incubator development, configurations, development, incubator-incubation impacts, and theorizing about incubators-incubation—problems with extant research are analyzed and opportunities for future research are identified. From our review, it is clear that research has just begun to scratch the surface of the incubator-incubation phenomenon. This chapter discusses the main results from the international cases studies and provides the conceptual framework and a thorough review of the international literature.