Public Health Gerontology and Active Aging

Chapter

Abstract

As a consequence of the reduction in birth rate and of the progressive increment in life expectancy, the population of Western nations is aging at a rate even faster than demographers’ projections with an unprecedented appearance of centenarians and super-centenarians. The peculiar aspects in this “epidemiological transition” require up-to-date knowledge to face a new type of “patient” and a joint effort of health professionals to target the negative aspects of aging, with a renewed attention toward primary prevention interventions, especially on the main modifiable risk factors. Currently, many studies underline how interventions targeting modifiable risk factors are cost-effective, and can potentially lead to cost reduction for health care organizations and society. From 2002, the World Health Organization (WHO) has defined the concept of “active aging” as “the process of optimizing opportunities for health, participation and security in order to enhance quality of life as people age,” but in the past years the “active aging” notion has evolved, pointing out that the aspects related with the promotion of healthy lifestyles must be started at an early age, but they are not able alone to guarantee a successful senescence and must be accompanied to a particular attention to the social and cultural aspects. This chapter aims to review the current evidences regarding the new challenge represented by the public health gerontology, helping health professionals and stakeholders to promote active aging and taking care of an aging population.

Keywords

Active aging Healthy aging Longevity Epidemiologic transition Aged Life expectancy Oldest old Prevention Policy 

References

  1. 1.
    Gorman M (1999) Development and the rights of older people. In: Randel J et al (Eds) The ageing and development report: poverty, independence and the world’s older people. Earthscan Publications Ltd, London, p 3–21Google Scholar
  2. 2.
    WHO (2013) Definition of an older or elderly person. http://www.who.int/healthinfo/survey/ageingdefnolder/en/index.html. Accessed 20 Aug 2013
  3. 3.
    Baltes PB, Smith J (2003) New frontiers in the future of aging: from successful aging of the young old to the dilemmas of the fourth age. Gerontology 49(2):123–135CrossRefPubMedGoogle Scholar
  4. 4.
    WHO (2013) Global health and aging. http://www.who.int/ageing/publications/global_health.pdf. Accessed 20 Aug 2013
  5. 5.
    WHO Regional Office for the Western Pacific (2013) Ageing and health a health promotion approach for developing countries. http://www.wpro.who.int/publications/pub_9290610662/en/index.html. Accessed 20 Aug 2013
  6. 6.
    Bowling A, Dieppe P (2005) What is successful ageing and who should define it? Br Med J 331:1548–1551CrossRefGoogle Scholar
  7. 7.
    WHO (2001) Active ageing makes the difference. http://www.who.int/ageing/publications/alc_embrace2001_en.pdf. Accessed 22 Aug 2013
  8. 8.
    WHO (2002) Active ageing: a policy frame work. http://whqlibdoc.who.int/hq/2002/WHO_NMH_NPH_02.8.pdf. Accessed 21 Aug 2013
  9. 9.
    Europe's response to world ageing—Promoting economic and social progress in an ageing world. A contribution of the European Commission to the 2nd World Assembly on Ageing. COM (2002) 143 Final. BrusselsGoogle Scholar
  10. 10.
    Oxley H (2009) Policies for healthy ageing: an overview. OECD health working papers. no 42. DELSA/HEA/WD/HWP (2009) 1Google Scholar
  11. 11.
    Vaillant GE (2002) Aging well: surprising guideposts to a happier life from the Landmark Harvard study of adult development. Little Brown, BostonGoogle Scholar
  12. 12.
    Ryff CD (1989) Beyond Ponce de Leon and life satisfaction: new directions in quest of successful aging. Int J Behav Dev 12:35–55CrossRefGoogle Scholar
  13. 13.
    Leon DA (2011) Trends in European life expectancy: a salutary view. Int J Epidemiol 40:271–277CrossRefPubMedGoogle Scholar
  14. 14.
    European Commission (2011) The 2012 ageing report: underlying assumptions and projection methodologies. Brussels: Joint Report prepared by the European Commission (DG ECFIN) and the Economic Policy Committee (AWG). European Economy 4/2011 37–45, 113–114Google Scholar
  15. 15.
    European Commission—Directorate-General for Economic and Financial Affairs (2012) The 2012 Ageing Report: economic and budgetary projections for the EU27 Member States (2010–2060). Joint Report prepared by the European Commission (DG ECFIN) and the Economic Policy Committee (AWG). EUROPEAN ECONOMY 2/2012 +Google Scholar
  16. 16.
    Kannisto V (2001) Development of oldest-old mortality, 1950–1990: evidence from 28 developed countries. Odense University Press, OdenseGoogle Scholar
  17. 17.
    Robine JM, Saito Y, Jagger C (2003) The emergence of extremely old people: the case of Japan. Exp Gerontol 38:735–739CrossRefPubMedGoogle Scholar
  18. 18.
    OECD (2011) Ageing, health and innovation: policy reforms to facilitate healthy and active ageing in OECD countries. OECD:delsa/hea (2011) 14Google Scholar
  19. 19.
    Stauner G (2008) The future of social security systems and demographic change. Eur View 7:203–208CrossRefGoogle Scholar
  20. 20.
    Bloom DE, Canning D (2008) Global demographic change: dimensions and economic significance. Popul Dev Rev 34:17–51Google Scholar
  21. 21.
    United Nations (2008) World population prospects, 2008 revisionGoogle Scholar
  22. 22.
    Centers for Disease Prevention and Control (2003) Public health and aging: trends in ageing—United States and worldwide. MMWR Weekly 52(6):101–106Google Scholar
  23. 23.
    Lagiewka K (2012) European innovation partnership on active and healthy ageing: triggers of setting the headline target of 2 additional healthy life years at birth at EU average by 2020. Arch Public Health 70(1):23CrossRefPubMedCentralPubMedGoogle Scholar
  24. 24.
    Fries JF, Bruce B, Chakravarty E (2011) Compression of morbidity 1980–2011: a focused review of paradigms and progress. J Aging Res 2011: 261702. doi:10.4061/2011/261702CrossRefPubMedCentralPubMedGoogle Scholar
  25. 25.
    Ahtonen A (2012). Healthy and active ageing: turning the ‘silver’ economy into gold. European Policy Centre. POLICY BRIEFGoogle Scholar
  26. 26.
    World Bank data. http://data.worldbank.org/country/united-states. Accessed 21 Aug 2013
  27. 27.
    Liberman SM, Lee J, Anderson T et al. (2003) Reducing the growth of medicare spending: geographic versus patient-based strategies. Health Aff (Millwood) (Suppl Web Exclusives) W3–603–13.Google Scholar
  28. 28.
    McKee M, Healy J (2002) Pressures for change. In: McKee M, Healy J (Eds) Hospitals in a changing Europe. Open University Press, Buckingham, p 36–58Google Scholar
  29. 29.
    Casey B et al (2003) Policies for an ageing society: recent measures and areas for further reform. OECD, ParisCrossRefGoogle Scholar
  30. 30.
    Anderson G, Hussey P (2001) Comparing health system performance in OECD countries. Health Affairs 20:219–232CrossRefPubMedGoogle Scholar
  31. 31.
    The European Union (2012) The council endorses the 2012 ageing report: economic and budgetary projections for the 27 EU Member States (2010–2060). European Economy 2012(2)Google Scholar
  32. 32.
    Rechel B et al (2009) Investing in hospitals of the future. WHO Regional Office for Europe, CopenhagenGoogle Scholar
  33. 33.
    Rechel B, Doyle Y, Grundy E, McKee M (2009) How can health systems respond to population ageing? Health Systems and Policy AnalysisGoogle Scholar
  34. 34.
    The Swedish National Institute of Public Health (2007) Healthy ageing: a challenge for Europe. HuskvarnaGoogle Scholar
  35. 35.
    Ramage-Morin PL, Shields M, Martel L (2010) Health-promoting factors and good health among Canadians in mid- to late life. Health Rep 21(3):45–53PubMedGoogle Scholar
  36. 36.
    Centers for Disease Control and Prevention and The Merck Company Foundation (2007) The state of aging and health in America 2007. The Merck Company Foundation, Whitehouse StationGoogle Scholar
  37. 37.
    Ljubuncic P, Globerson A, Reznick AZ (2008) Evidence-based roads to the promotion of health in old age. J Nutr Health Aging 12(2):139–143CrossRefPubMedGoogle Scholar
  38. 38.
    Peel NM, McClure RJ, Bartlett HP (2005) Behavioral determinants of healthy aging. Am J Prev Med 28(3):298–304CrossRefPubMedGoogle Scholar
  39. 39.
    Newman AB, Arnold AM, Naydeck BL et al (2003) Successful aging: effect of subclinical cardiovascular disease. Arch Intern Med 163:2315–2322CrossRefPubMedGoogle Scholar
  40. 40.
    Vaillant GE, Mukamal K (2011) Successful aging. Am J Psychiatry 158:839–847CrossRefGoogle Scholar
  41. 41.
    Rimm EB, Klatsky A, Grobbee D, Stampfer MJ (1996) Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits. BMJ 312(7033):731–736CrossRefPubMedCentralPubMedGoogle Scholar
  42. 42.
    Ilomäki J, Paljärvi T, Korhonen MJ et al (2013) Prevalence of concomitant use of alcohol and sedative-hypnotic drugs in middle and older aged persons: a systematic review. Ann Pharmacother 47(2):257–268CrossRefPubMedGoogle Scholar
  43. 43.
    Meier P, Seitz HK (2008) Age, alcohol metabolism and liver disease. Curr Opin Clin Nutr Metab Care 11:21–26CrossRefPubMedGoogle Scholar
  44. 44.
    Alcohol Research UK (2011) Working with older drinkers. Alcohol Research, LondonGoogle Scholar
  45. 45.
    Reid MC, Boutros NN, O’Connor PG, Cadariu A, Concato J (2002) The health-related effects of alcohol use in older persons: a systematic review. Subst Abus 23(3):149–164PubMedGoogle Scholar
  46. 46.
    Panza F, Capurso C, D'Introno A et al (2009) Alcohol drinking, cognitive functions in older age, predementia, and dementia syndromes. J Alzheimers Dis 17(1):7–31PubMedGoogle Scholar
  47. 47.
    Peters R, Peters J, Warner J, Beckett N, Bulpitt C (2008) Alcohol, dementia and cognitive decline in the elderly: a systematic review. Age Ageing 37(5):505–512CrossRefPubMedGoogle Scholar
  48. 48.
    Anderson P, Scafato E, Galluzzo L, VINTAGE project Working Group (2012) Alcohol and older people from a public health perspective. Ann Ist Super Sanita 48(3):232–247CrossRefPubMedGoogle Scholar
  49. 49.
    Sayer AA, Syddall HE, Gilbody HJ, Dennison EM, Cooper C (2004) Does sarcopenia originate in early life? Findings from the Hertfordshire Cohort Study. J Gerontol 59A:930–934CrossRefGoogle Scholar
  50. 50.
    Robinson SM, Simmonds SJ, Jameson KA et al (2012) Muscle strength in older community-dwelling men is related to type of milk feeding in infancy. J Geront A Biol Sci Med Sci 67:990–996CrossRefGoogle Scholar
  51. 51.
    Sayer AA, Robinson SM, Patel HP, Shavlakadze T, Cooper C, Grounds MD (2013) New horizons in the pathogenesis, diagnosis and management of sarcopenia. Age Ageing 42(2):145–150. doi:10.1093/ageing/afs191CrossRefPubMedCentralPubMedGoogle Scholar
  52. 52.
    Cooper R, Kuh D, Hardy R (2010) Objectively measured physical capability levels and mortality: systematic review and meta-analysis. Br Med J 341:c4467CrossRefGoogle Scholar
  53. 53.
    Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R (2004) The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc 52:80–85CrossRefPubMedGoogle Scholar
  54. 54.
    Nieuwenhuizen WF, Weenen H, Rigby P, Hetherington MM (2010) Older adults and patients in need of nutritional support: review of current treatment options and factors influencing nutritional intake. Clin Nutr 29(2):160–169. doi:10.1016/j.clnu.2009.09.003CrossRefPubMedGoogle Scholar
  55. 55.
    Murphy C (2008) The chemical senses and nutrition in older adults. J Nutr Elder 27(3–4):247–265CrossRefPubMedGoogle Scholar
  56. 56.
    Robinson S, Cooper C, Aihie SA (2012) Nutrition and sarcopenia: a review of the evidence and implications for preventive strategies. J Aging Res 2012:510801Google Scholar
  57. 57.
    Houston DK, Nicklas BJ, Ding J et al (2008) Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr 87:150–155PubMedGoogle Scholar
  58. 58.
    Milne AC, Potter J, Vivanti A, Avenell A (2009) Protein and energy supplementation in elderly people at risk from malnutrition. Cochrane Database Syst Rev 15(2):CD003288. doi:10.1002/14651858.CD003288.pub3Google Scholar
  59. 59.
    Guo SS, Wu W, Chumlea WC, Roche AF (2002) Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr 76:653–658PubMedGoogle Scholar
  60. 60.
    Guo SS, Roche AF, Chumlea WC, Gardner JD, Siervogel RM (1994) The predictive value of childhood body mass index values for overweight at age 35 y. Am J Clin Nutr 59:810–819PubMedGoogle Scholar
  61. 61.
    McNaughton SA, Crawford D, Ball K, Salmon J (2012) Understanding determinants of nutrition, physical activity and quality of life among older adults: the Wellbeing, Eating and Exercise for a Long Life (WELL) study. Health Qual Life Outcomes 10:109CrossRefPubMedCentralPubMedGoogle Scholar
  62. 62.
    Shepherd A (2009) Nutrition through the life span. Part 3: adults aged 65 years and over. Br J Nur 18(5):301–307CrossRefGoogle Scholar
  63. 63.
    Robinson SM, Jameson KA, Batelaan SF et al (2008) Diet and its relationship with grip strength in community-dwelling older men and women: the Hertfordshire cohort study, J Am Geriatr Soc 56(1):84–90CrossRefPubMedCentralPubMedGoogle Scholar
  64. 64.
    Södergren M, McNaughton SA, Salmon J, Ball K, Crawford DA (2012) Associations between fruit and vegetable intake, leisure-time physical activity, sitting time and self-rated health among older adults: cross-sectional data from the WELL study. BMC Public Health 12:551CrossRefPubMedCentralPubMedGoogle Scholar
  65. 65.
    Bandayrel K, Wong S (2011) Systematic literature review of randomized control trials assessing the effectiveness of nutrition interventions in community-dwelling older adults. J Nutr Educ Behav 43:251–262CrossRefPubMedGoogle Scholar
  66. 66.
    Cooper R, Kuh D, Hardy R, Mortality Review Group, FALCon and HALCyon Study Teams (2010) Objectively measured physical capability levels and mortality: systematic review and meta-analysis. Br Med J 341:c4467CrossRefGoogle Scholar
  67. 67.
    Pedersen BK, Saltin B (2006) Evidence for prescribing exercise as therapy in chronic disease. Scand J Med Sci Sports 16(S1):3–63CrossRefPubMedGoogle Scholar
  68. 68.
    Walker KZ, O'Dea K, Gomez M, Girgis S, Colagiuri R (2010) Diet and exercise in the prevention of diabetes. J Hum Nutr Diet 23(4):344–352CrossRefPubMedGoogle Scholar
  69. 69.
    Kelley GA, Kelley KS (2006) Aerobic exercise and HDL2-C: a meta-analysis of randomized controlled trials. Atherosclerosis 184(1): 207–215CrossRefPubMedCentralPubMedGoogle Scholar
  70. 70.
    Adami PE, Negro A, Lala N, Martelletti P (2010) The role of physical activity in the prevention and treatment of chronic diseases. Clinica Clin Ter 161(6):537–541Google Scholar
  71. 71.
    Warburton DE, Charlesworth S, Ivey A, Nettlefold L, Bredin SS (2010) A systematic review of the evidence for Canada's Physical Activity Guidelines for Adults. Int J Behav Nutr Phys Act 7:39CrossRefPubMedCentralPubMedGoogle Scholar
  72. 72.
    Lee CD, Folsom AR, Blair SN (2003) Physical activity and stroke risk. A meta-analysis. Stroke 34:2475–2482CrossRefPubMedGoogle Scholar
  73. 73.
    Halle M, Schoenberg MH (2009) Physical activity in the prevention and treatment of colorectal carcinoma. Dtsch Arztebl Int 106(44):722–727PubMedCentralPubMedGoogle Scholar
  74. 74.
    Monninkhof EM, Elias SG, Vlems FA et al (2007) Physical activity and breast cancer: a systematic review. Epidemiology 18(1):137–157CrossRefPubMedGoogle Scholar
  75. 75.
    Reimers CD, Knapp G, Reimers AK (2012) Does physical activity increase life expectancy? A review of the literature. J Aging Res 2012:243958CrossRefPubMedCentralPubMedGoogle Scholar
  76. 76.
    Nusselder WJ, Looman CW, Franco OH, Peeters A, Slingerland AS, Mackenbach JP (2008) The relation between non-occupational physical activity and years lived with and without disability. Epidemiol Community Health 62(9):823–828CrossRefGoogle Scholar
  77. 77.
    Dunsky A, Netz Y (2012) Physical activity and sport in advanced age: is it risky? A summary of data from articles published between 2000–2009. Curr Aging Sci 5(1):66–71CrossRefPubMedGoogle Scholar
  78. 78.
    Paillard-Borg S, Fratiglioni L, Xu W, Winblad B, Wang HX (2012) An active lifestyle postpones dementia onset by more than one year in very old adults. J Alzheimers Dis 31(4):835–842PubMedGoogle Scholar
  79. 79.
    Callaghan P (2004) Exercise: a neglected intervention in mental health care? J Psychiatr Ment Health Nurs 11(4):476–483CrossRefPubMedGoogle Scholar
  80. 80.
    Landi F, Abbatecola AM, Provinciali M (2010) Moving against frailty: does physical activity matter? Biogerontology 11(5):537–545CrossRefPubMedGoogle Scholar
  81. 81.
    Angevaren M, Aufdemkampe G, Verhaar HJ, Aleman A, Vanhees L (2008) Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. Cochrane Database Syst Rev (3):CD005381Google Scholar
  82. 82.
    Figueira HA, Figueira AA, Cader SA et al (2012) Effects of a physical activity governmental health programme on the quality of life of elderly people. Scand J Public Health 40(5):418–422CrossRefPubMedGoogle Scholar
  83. 83.
    Liu CJ, Latham NK (2009) Progressive resistance strength training for improving physical function in older adults. Cochrane Database Syst Rev (3):CD002759Google Scholar
  84. 84.
    Samitz G, Egger M, Zwahlen M (2011) Domains of physical activity and all-cause mortality: systematic review and doseresponse meta-analysis of cohort studies. Int J Epidemiol 40(5):1382–1400CrossRefPubMedGoogle Scholar
  85. 85.
    Munro J, Brazier J, Davey R, Nicholl J (1997) Physical activity for the over-65s: could it be a cost-effective exercise for the NHS? J Public Health Med 19(4):397–402CrossRefPubMedGoogle Scholar
  86. 86.
    Munro JF, Nicholl JP, Brazier JE, Davey R, Cochrane T (2003) Cost effectiveness of a community based exercise programme in over 65 year olds: cluster randomised trial. J Epidemiol Community Health 58(12):1004–1010CrossRefGoogle Scholar
  87. 87.
    Rhodes RE, Mark RS, Temmel CP (2012) Adult sedentary behavior: a systematic review. Am J Prev Med 42(3):e3–e28CrossRefPubMedGoogle Scholar
  88. 88.
    Inoue S, Sugiyama T, Takamiya T, Oka K, Owen N, Shimomitsu T (2012) Television viewing time is associated with overweight/obesity among older adults, independent of meeting physical activity and health guidelines. J Epidemiol 22(1):50–56CrossRefPubMedCentralPubMedGoogle Scholar
  89. 89.
    Hill K et al (2004) An analysis of research on preventing falls and falls injury in older people: community, residential care and hospital settings (2004 update). National Ageing Research Institute and Centre for Applied Gerontology, report to the Australian Government, Department of Health and Ageing, Injury Prevention Section: Melbourne.Google Scholar
  90. 90.
    Stevens JA, Corso PS, Finkelstein EA, Miller TR (2006) The cost of fatal and non-fatal falls among older adults. Injury Prevention 12:290–295CrossRefPubMedCentralPubMedGoogle Scholar
  91. 91.
    Gillespie LD, Robertson MC, Gillespie WJ, Gates S, Clemson LM, Lamb SE (2012) Interventions for preventing falls in elderly people. Cochrane Database Syst Rev 9:CD007146PubMedGoogle Scholar
  92. 92.
    Cameron ID, Gillespie LD, Robertson MC et al (2012) Interventions for preventing falls in older people in care facilities and hospitals. Cochrane Database Syst Rev 12:CD005465PubMedGoogle Scholar
  93. 93.
    Neyens JC, van Haastregt JC, Dijcks BP et al (2011) Effectiveness and implementation aspects of interventions for preventing falls in elderly people in long-term care facilities: a systematic review of RCTs. J Am Med Dir Assoc 12(6):410–425CrossRefPubMedGoogle Scholar
  94. 94.
    McClure R, Turner C, Peel N, Spinks A, Eakin E, Hughes K (2005) Population-based interventions for the prevention of fall-related injuries in older people. Cochrane Database Syst Rev (1):CD004441Google Scholar
  95. 95.
  96. 96.
    Kempton A et al (2000) Older people can stay on their feet: final results of a community-based falls prevention programme. Health Promot Int 15(1):27–33CrossRefGoogle Scholar
  97. 97.
    Robertson MC, Gardner MM, Devlin N, McGee R, Campbell AJ (2001) Effectiveness and economic evaluation of a nurse delivered home exercise programme to prevent falls. Controlled trial in multiple centres. Br Med J 322(7288):701–704CrossRefGoogle Scholar
  98. 98.
    Wilson C, Datta K (2001) Tai Chi for prevention of fractures in a nursing home population: an economic analysis. J Clin Outcomes Manag 8:19–27Google Scholar
  99. 99.
    Schrijvers EM, Verhaaren BF, Koudstaal PJ, Hofman A, Ikram MA, Breteler MM (2012) Is dementia incidence declining? Trends in dementia incidence since 1990 in the Rotterdam Study. Neurology 78:1456–1463CrossRefPubMedGoogle Scholar
  100. 100.
    WHO (2012) Mental Health Gap Action Programme (mhGAP). http://www.who.int/mental_health/mhGAP_nl_June_2012.pdf. Accessed 17 Aug 2013
  101. 101.
    WHO (2012) Dementia: a public health priority. WHO, Geneva. http://whqlibdoc.who.int/publications/2012/9789241564458_eng.pdf. Accessed 17 Aug 2013
  102. 102.
    Solomon A, Sippola R, Soininen H et al (2010) Lipid-lowering treatment is related to decreased risk of dementia: a population-based study (FINRISK). Neurodegener Dis 7(1–3):180–182. doi:10.1159/000295659CrossRefPubMedGoogle Scholar
  103. 103.
    Rovio S, Kåreholt I, Helkala EL et al (2005) Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease. Lancet Neurol 4(11):705–711CrossRefPubMedGoogle Scholar
  104. 104.
    Frisardi V, Panza F, Seripa D et al (2010) Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms. J Alzheimers Dis 22(3):715–740. doi:10.3233/JAD-2010-100942PubMedGoogle Scholar
  105. 105.
    Xu WL, Qiu CX, Wahlin A, Winblad B, Fratiglioni L (2004) Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology 63(7):1181–1186CrossRefPubMedGoogle Scholar
  106. 106.
    National Center for Health Statistics (2007) Trends in health and aging. Trends in causes of death among older persons in the United States. http://www.cdc.gov/nchs/agingact.htm. Accessed 16 Aug 2007
  107. 107.
    Thompson WW, Matthew R et al (2009) Estimating influenza-associated deaths in the United States. Am J Public Health 99(2):S225–S230. doi:10.2105/AJPH.2008.151944CrossRefPubMedGoogle Scholar
  108. 108.
    Ludwig E, Unal S, Bogdan M et al (2012) Opportunity for healthy ageing: lessening the burden of adult pneumococcal disease in Central and Eastern Europe, and Israel. Cent Eur J Public Health 20(2):121–125PubMedGoogle Scholar
  109. 109.
    Assaad U, El-Masri I, Porhomayon J, El-Solh AA (2012) Pneumonia immunization in older adults: review of vaccine effectiveness and strategies. Clin Interv Aging 7:453–461PubMedCentralPubMedGoogle Scholar
  110. 110.
    Goronzy JJ, Weyand CM (2013) Understanding immunosenescence to improve responses to vaccines. Nat Immunol 14(5):428–436CrossRefPubMedCentralPubMedGoogle Scholar
  111. 111.
    Goodwin K, Viboud C, Simonsen L (2006) Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine 24(8):1159–1169CrossRefPubMedGoogle Scholar
  112. 112.
    Weinberger B, Grubeck-Loebenstein B (2012) Vaccines for the elderly. Clin Microbiol Infect. 18(5):100–108. doi:10.1111/j.1469-0691.2012.03944.xCrossRefPubMedGoogle Scholar
  113. 113.
    Derhovanessian E, Pawelec G (2012) Vaccination in the elderly. Microb Biotechnol 5(2):226–232CrossRefPubMedCentralPubMedGoogle Scholar
  114. 114.
    Centers for Disease Control and Prevention (CDC) (2006) Recommended adult immunization schedule: United States, October 2006-September 2007. MMWR Morb Mortal Wkly Rep 55:Q1–Q4Google Scholar
  115. 115.
    Bader M.S (2007) Immunization for the elderly. Am J Med Sci 334(6):481–486CrossRefPubMedGoogle Scholar
  116. 116.
    Nicholas JA, Hall WJ (2011) Screening and preventive services for older adults. Mt Sinai J Med 78(4):498–508CrossRefPubMedCentralPubMedGoogle Scholar
  117. 117.
    Flaherty JH (2008) Cancer screening in older patients: life expectancy, prioritization, and health literacy. Am Fam Physician 78(12):1336–1338PubMedGoogle Scholar
  118. 118.
    Terret C, Castel-Kremer E, Albrand G, Droz JP (2009) Effects of comorbidity on screening and early diagnosis of cancer in elderly people. Lancet Oncol 10(1):80–87. doi:10.1016/S1470-2045(08)70336-XCrossRefPubMedGoogle Scholar
  119. 119.
    Clarfield AM (2010). Screening in frail older people: an ounce of prevention or a pound of trouble? J Am Geriatr Soc 58(10):2016–2021CrossRefPubMedGoogle Scholar
  120. 120.
    Hoffe S, Balducci L (2012) Cancer and age: general considerations. Clin Geriatr Med 28(1):1–18CrossRefPubMedGoogle Scholar
  121. 121.
    Eckstrom E, Feeny DH, Walter LC, Perdue LA, Whitlock EP (2013) Individualizing cancer screening in older adults: a narrative review and framework for future research. J Gen Int Med 28(2):292–298CrossRefGoogle Scholar
  122. 122.
    Albert RH, Clark MM (2008) Cancer screening in the older patient. Am Fam Physician 78(12):1369–1374, 1376PubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Andrea Poscia
    • 1
  • Francesco Landi
    • 2
  • Agnese Collamati
    • 2
  1. 1.Institute of Public Health, Section of HygieneUniversità Cattolica del Sacro CuoreRomeItaly
  2. 2.Institute of GerontologyUniversità Cattolica del Sacro CuoreRomeItaly

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