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Tracking Red Blood Cells Flowing through a Microchannel with a Hyperbolic Contraction: An Automatic Method

  • B. Taboada
  • F. C. Monteiro
  • R. Lima
Chapter
Part of the Lecture Notes in Computational Vision and Biomechanics book series (LNCVB, volume 19)

Abstract

The present chapter aims to assess the motion and deformation index of red blood cells (RBCs) flowing through a microchannel with a hyperbolic contraction using an image analysis based method. For this purpose, a microchannel containing a hyperbolic contraction was fabricated in polydimethylsiloxane by using a soft-lithography technique and the images were captured by a standard high-speed microscopy system. An automatic image processing and analyzing method has been developed in a MATLAB environment, not only to track both healthy and exposed RBCs motion but also to measure the deformation index along the microchannel. The keyhole model has proved to be a promising technique to track automatically healthy and exposed RBCs flowing in this kind of microchannels.

Keywords

Optical Flow Bilateral Filter Atomic Region Motion Segmentation Deformation Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgements

The authors acknowledge the financial support provided by PTDC/SAUBEB/105650/2008, PTDC/SAU-ENB/116929/2010, EXPL/EMS-SIS/2215/2013 from FCT (Science and Technology Foundation), COMPETE, QREN and European Union (FEDER).

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.ESTiG, IPB, C. Sta. ApoloniaBragançaPortugal
  2. 2.CEFT, FEUP, R. Dr. Roberto FriasPortoPortugal
  3. 3.University of MinhoMechanical Engineering DepartmentGuimarãesPortugal

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