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Coccidioidomycosis

  • Royce H. JohnsonEmail author
  • Arash Heidari
Chapter
Part of the Infectious Disease book series (ID)

Abstract

Coccidioidomycos (CM) is a fungal infection caused by the endemic thermal dysmorphic fungal genus Coccidioides. The illness is usually acquired in the southwestern USA and adjacent areas of Mexico. Primary infection is virtually always pneumonic disease. Disseminated disease may occur in individuals with antecedent pulmonary disease or as a presenting manifestation. Dissemination can occur to any site, but disease of skin, bone, joint, and meninges is most common.

Therapy is complex, often protracted and less than ideal. The primary agents are azoles and amphotericin compounds. Relapses are common.

Keywords

Coccidioidomycosis Coccidioides Fungal infections Fungal pneumonia Fungal osteomyelitis Fungal meningitis Fungal synovitis Fungal skin lesions 

Notes

Acknowledgment

The authors wish to thank D. Caldwell, J. Pusavat, and the recently deceased H. Einstein for their help and/or advice in the preparation of this chapter.

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Suggested Reading

  1. Galgiani JN. Coccidioides species. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. 6th ed. Philadelphia: Elsevier Churchill Livingstone; 2005. p. 3040–51.Google Scholar
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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Department of MedicineDavid Geffen School of Medicine at University of California Los AngelesLos AngelesUSA
  2. 2.Department of MedicineKern Medical CenterBakersfieldUSA
  3. 3.Internal Medicine, Division of Infectious DiseasesKern Medical CenterBakersfieldUSA

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