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Obsessive-Compulsive Disorder

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Anxiety Disorders and Gender

Abstract

Previously classified as an anxiety-related disorder, obsessive-compulsive disorder (OCD) was moved to a new “Obsessive-Compulsive and Related Disorders” section in the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association [APA], 2013). This section also includes body dysmorphic disorder (BDD), hoarding disorder (previously considered a subtype of OCD), trichotillomania (hair-pulling disorder), and excoriation (skin-picking disorder; APA 2013) (see Chap. x). In DSM-5, OCD is characterized by the presence of obsessions and compulsions (Criterion A), which must be time-consuming or cause clinically significant distress or impairment (Criterion B; APA 2013, p. 238). Obsessions are egodystonic “repetitive and persistent thoughts, images, or urges” (APA 2013, p. 238), while compulsions are “repetitive behaviors … that the individual feels driven to perform in response to an obsession or according to rules that must be applied rigidly” (APA 2013, p. 237). Whereas obsessions are strictly mental activities, compulsions can be observable (e.g., checking locks or washing hands) or covert (e.g., counting or mentally repeating certain words or phrases).

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References

  • Abramovitch A, Mittleman A, Henin A, Geller D (2012) Neuroimaging and neuropsychological findings in pediatric obsessive-compulsive disorder: a review and developmental considerations. Neuropsychiatry 2(4):313–329

    Google Scholar 

  • Abramowitz JS (1997) Effectiveness of psychological and pharmacological treatments for obsessive-compulsive disorder: a quantitative review. J Consult Clin Psychol 65(1):44–52

    CAS  PubMed  Google Scholar 

  • Abramowitz JS (2006) The psychological treatment of obsessive-compulsive disorder. Can J Psychiatry 51(7):407–416

    PubMed  Google Scholar 

  • Abramowitz JS, Franklin ME, Foa EB (2002) Empirical status of cognitive-behavioral therapy for obsessive-compulsive disorder: a meta-analytic review. Rom J Cogn Behav Psychotherapies 2:89–104

    Google Scholar 

  • Abramowitz JS, Schwartz SA, Moore KM (2003a) Obsessional thoughts in postpartum females and their partners: content, severity, and relationship with depression. J Clin Psychol Med Settings 10(3):157–164

    Google Scholar 

  • Abramowitz JS, Schwartz SA, Moore KM, Luenzmann KR (2003b) Obsessive-compulsive symptoms in pregnancy and the puerperium: a review of the literature. J Anxiety Disord 17(4):461–478

    PubMed  Google Scholar 

  • Abramowitz JS, Taylor S, McKay D (2009) Obsessive-compulsive disorder. Lancet 374:491–499

    PubMed  Google Scholar 

  • Achenbach TM (1991) Integrative guide for the 1991 CBCL/4-18, YSR, and TRF profiles. University of Vermont, Department of Psychiatry, Burlington

    Google Scholar 

  • Ackerman DL, Greenland S (2002). Multivariate meta-analysis of controlled drug studies for obsessive-compulsive disorder. Journal of clinical psychopharmacology, 22(3), 309–317

    Google Scholar 

  • Alexander GE, Crutcher MD (1990) Functional architecture of the basal ganglia circuits: Neural substrates of parallel processing. Trends Neurosci 13(7):266–271

    CAS  PubMed  Google Scholar 

  • American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. Author, Washington, DC

    Google Scholar 

  • American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Publishing, Arlington

    Google Scholar 

  • Aouizerate B, Guehl D, Cuny E, Rougier A, Bioulac B, Tignol J, Burband P (2004) Pathophysiology of obsessive-compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery, and physiology. Prog Neurobiol 73(3):195–221

    Google Scholar 

  • Apter A, Fallon TJ, King RA, Ratzoni G, Zohar AH, Binder M, Weizman A, Leckman JF, Pauls DL, Kron S, Cohen DJ (1996) Obsessive-compulsive characteristics: from symptoms to syndrome. J Am Acad Child Adolesc Psychiatr 35(7):907–912

    CAS  Google Scholar 

  • Arnold LM (1999) A case series of women with postpartum-onset obsessive-compulsive disorder. Prim Care Companion J Clin Psychiatr 1(4):103–108

    Google Scholar 

  • Arnold PD, Sicard T, Burroughs E, Richter MA, Kennedy JL (2006) Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. Arch Gen Psychiatry 63(7):769–776

    CAS  PubMed  Google Scholar 

  • Aylward EH, Harris GJ, Hoehn-Saric R, Barta PE, Machlin SR, Pearlson GD (1996) Normal caudate nucleus in obsessive-compulsive disorder assessed by quantitative neuroimaging. Arch Gen Psychiatry 53:577–584

    CAS  PubMed  Google Scholar 

  • Baer L, Jenike MA (1992) Personality disorders in obsessive compulsive disorder. Psychiatr Clin North Am 15(4):803–812

    CAS  PubMed  Google Scholar 

  • Bebbington PE (1998) Epidemiology of obsessive-compulsive disorder. Br J Psychiatr Suppl 35:2–6

    Google Scholar 

  • Berlim MT, Neufeld NH, Van den Eyne F (2013) Repetitive transcranial magnetic stimulation (rTMS) for obsessive-compulsive disorder (OCD): an exploratory meta-analysis of randomized and sham-controlled trials. J Psychiatr Res 47(8):999–1006

    PubMed  Google Scholar 

  • Bloch MH, McGuire J, Landeros-Weisenberger A, Leckman JF, Pittenger C (2010). Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder. Molecular psychiatry, 15(8), 850–855

    Google Scholar 

  • Bogetto F, Venturello S, Albert U, Maina G, Ravizza L (1999) Gender-related clinical differences in obsessive-compulsive disorder. Eur Psychiatry 14(8):434–441

    CAS  PubMed  Google Scholar 

  • Brown TA, Di Nardo PA, Barlow DH (1994) Anxiety Disorders Interview Schedule for DSM-IV: adult and lifetime version, clinician manual. Graywind Publications, Albany

    Google Scholar 

  • Burns LG, Keortage SG, Formea GM, Sternberger LG (1996) Revision of the Padua inventory of obsessive compulsive disorder symptoms: distinctions between worry, obsessions, and compulsions. Behav Res Ther 34:163–173

    CAS  PubMed  Google Scholar 

  • Buttolph ML, Holland AD (1990) Obsessive-compulsive disorders in pregnancy and childbirth. In: Jenike MA, Baer L, Minichiello WE (eds) Obsessive-compulsive disorder: theory and management, 2nd edn. Yearbook Medical Publishers, Chicago, pp 89–95

    Google Scholar 

  • Castle DJ, Deale A, Marks IM (1995) Gender differences in obsessive compulsive disorder. Aust N Z J Psychiatr 29(1):114–117

    CAS  Google Scholar 

  • Chambless DL, Baker MJ, Baucom DH, Beutler LE, Calhoun KS, Crits-Christoph P, Daiuto A, DeRubeis R, Detweiler J, Haaga DAF, Bennett Johnson S, McCurry S, Mueser KT, Pope KS, Sanderson WC, Shoham V, Stickle T, Williams DA, Woody SR (1998) Update on empirically validated therapies, II. Clin Psychol 51(1):3–16

    Google Scholar 

  • Chaudron LH, Nirodi N (2010) The obsessive–compulsive spectrum in the perinatal period: a prospective pilot study. Arch Womens Ment Health 13(5):403–410

    PubMed Central  PubMed  Google Scholar 

  • Chelmow D, Halfin VP (1997) Pregnancy complicated by obsessive-compulsive disorder. J Matern Fetal Med 6(1):31–34

    CAS  PubMed  Google Scholar 

  • Christian LM, Storch EA (2009) Cognitive behavioral treatment of postpartum onset obsessive compulsive disorder with aggressive obsessions. Clin Case Stud 8(1):72–83

    Google Scholar 

  • Coles ME, Pinto A, Mancebo MC, Rasmussen SA, Eisen JL (2008) OCD with comorbid OCPD: a subtype of OCD? J Psychiatr Res 42(4):289–296

    PubMed  Google Scholar 

  • de Mathis MA, Alvarenga PD, Funaro G, Torresan RC, Moraes I, Torres AR, Zilberman ML, Hounie AG (2011) Gender differences in obsessive-compulsive disorder: a literature review. Rev Bras Psiquiatr 33(4):390–399

    PubMed  Google Scholar 

  • Decloedt EH, Stein DJ (2010). Current trends in drug treatment of obsessive–compulsive disorder. Neuropsychiatric disease and treatment, 6, 233

    Google Scholar 

  • Dell’Osso B, Altamura AC, Allen A, Marazziti D, Hollander E (2006) Epidemiologic and clinical updates on impulse control disorders: a critical review. Eur Arch Psychiatry Clin Neurosci 256(8):464–475

    PubMed Central  PubMed  Google Scholar 

  • DeRubeis RJ, Crits-Christoph P (1998) Empirically supported individual and group psychological treatments for adult mental disorders. J Consult Clin Psychol 66(1):37–52

    CAS  PubMed  Google Scholar 

  • Dickel DE, Veenstra-VanderWeele J, Cox NJ, Wu X, Fischer DJ, Van Etten-Lee M, Himle JA, Leventhal BL, Cook EH Jr, Hanna GL (2006) Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. Arch Gen Psychiatry 63(7):778–785

    CAS  PubMed  Google Scholar 

  • Diler RS, Kibar M, Avci A (2004) Psychotherapy and regional cerebral blood flow in children with obsessive compulsive disorder. Yonsei Med J 45(1):90–99

    PubMed  Google Scholar 

  • Eisen JL, Phillips KA, Baer L, Beer DA, Atala KD, Rasmussen SA (1998) The brown assessment of beliefs scale: reliability and validity. Am J Psychiatr 155(1):102–108

    CAS  PubMed  Google Scholar 

  • Enoch M, Greenberg BD, Murphy DL, Goldman D (2001) Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive compulsive disorder. Biol Psychiatry 49(4):385–388

    CAS  PubMed  Google Scholar 

  • Fairbrother N, Abramowitz JS (2007) New parenthood as a risk factor for the development of obsessional problems. Behav Res Ther 45(9):2155–2163

    PubMed  Google Scholar 

  • Feske U, Chambless DL (2000) A review of assessment measures for obsessive-compulsive disorder. In: Goodman WK, Rudorfer MV, Maser JD (eds) Obsessive-compulsive disorder: contemporary issues in treatment. Lawrence Erlbaum Associates Publishers, Mahwah, pp 157–182

    Google Scholar 

  • Fineberg NA, Gale TM, Sivakumaran T (2006) A review of antipsychotics in the treatment of obsessive compulsive disorder. J Psychopharmacol 20(1):97–103

    CAS  PubMed  Google Scholar 

  • Fineberg NA, Reghunandanan S, Brown A, Pampaloni I (2013) Pharmacotherapy of obsessive-compulsive disorder: evidence-based treatment and beyond. Aust N Z J Psychiatr 47(2):121–141

    Google Scholar 

  • First MB, Spitzer RL, Gibbon M, Williams JBW (1996) Structured clinical interview for DSM-IV axis I disorders, clinician version (SCID-CV). American Psychiatric Press, Inc., Washington, DC

    Google Scholar 

  • Flosnik DL, Khin EK (2012) Cognitive-behavioral therapy for obsessive-compulsive disorder in pregnancy. Psychiatr Ann 42(7):269–271

    Google Scholar 

  • Foa EB, Huppert JD, Leiberg S, Langner R, Kichic R, Hajcak G, Salkovskis PM (2002) The obsessive–compulsive inventory: development and validation of a short version. Psychol Assess 14(4):485–496

    PubMed  Google Scholar 

  • Foa EB, Yadin E, Lichner TK (2012) Exposure and response (ritual) prevention for obsessive-compulsive disorder: therapist guide. Oxford University Press, New York

    Google Scholar 

  • Forray A, Focseneanu M, Pittman B, McDougle CJ, Epperson CN (2010) Onset and exacerbation of obsessive-compulsive disorder in pregnancy and the postpartum period. J Clin Psychiatry 71(8):1061–1068

    PubMed Central  PubMed  Google Scholar 

  • Frost RO, Steketee G, Tolin DF (2012) Diagnosis and assessment of hoarding disorder. Annu Rev Clin Psychol 8:219–242

    PubMed  Google Scholar 

  • Geller DA, March J, Walter HJ, Bukstein OG, Benson RS, Chrisman A, Farchione TR, Hamilton J, Keable H, Kinlan J, Schoettle U, Siegel M, Stock S (2012) Practice parameter for the assessment and treatment of children and adolescents with obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry 51:98–113

    Google Scholar 

  • Giedd JN, Rapoport JL, Garvey MA, Perlmutter S, Swedo SE (2000) MRI assessment of children with obsessive-compulsive disorders or tics associated with streptococcal infection. Am J Psychiatry 157(2):281–283

    CAS  PubMed  Google Scholar 

  • Gilbert AR, Moore GJ, Keshavan MS, Paulson LD, Narula V, MacMaster FP, Stewart CM, Rosenberg DR (2000) Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine. Arch Gen Psychiatry 57(5):449–456

    CAS  PubMed  Google Scholar 

  • Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS (1989) The Yale-brown obsessive compulsive scale: I. development, use, and reliability. Arch Gen Psychiatry 46(11):1006–1011

    CAS  PubMed  Google Scholar 

  • Graybiel AM, Rauch SL (2000) Toward a neurobiology of obsessive-compulsive disorder. Neuron 28(2):343–347

    CAS  PubMed  Google Scholar 

  • Greenberg BD, Malone DA, Friehs GM, Rezai AR, Kubu CS, Malloy PF, Salloway SP, Okun MS, Goodman WK, Rasmussen SA (2006) Three year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorder. Neuropsychopharmacology 31:2384–2393

    PubMed  Google Scholar 

  • Greist J, Chouinard G, DuBoff E, Halaris A, Kim SW, Koran L, Sikes, C (1995). Double-blind parallel comparison of three dosages of sertraline and placebo in outpatients with obsessive-compulsive disorder. Archives of General Psychiatry, 52(4), 289–295

    Google Scholar 

  • Hanna GL (1995) Demographic and clinical features of obsessive-compulsive disorder in children and adolescents. J Am Acad Child Adolesc Psychiatry 34(1):19–27

    CAS  PubMed  Google Scholar 

  • Hanna GL, Veenstra-VanderWeele J, Cox NJ, Boehnke M, Himle JA, Curtis GC, Leventhal BL, Cook EH (2002) Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands. Am J Med Genet 114:541–552

    PubMed  Google Scholar 

  • Harrison BJ, Soriano-Mas C, Pujol J, Ortiz H, López-Solà M, Hernández-Ribas R, Deus J, Alonso P, Yücel M, Pantelis C, Menchon JM, Cardoner N (2009) Altered corticostriatal functional connectivity in obsessive-compulsive disorder. Arch Gen Psychiatry 66(11):1189–2000

    PubMed  Google Scholar 

  • Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Taubman J, Greenberg BD, Xu K, Arnold PD, Richter MA, Kennedy JL, Murphy DL, Goldman D (2006) Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 78(5):815–826

    PubMed Central  CAS  PubMed  Google Scholar 

  • Jaisoorya TS, Janardhan Reddy YC, Srinath S, Thennarasu K (2009) Sex differences in Indian patients with obsessive-compulsive disorder. Compr Psychiatry 50(1):70–75

    CAS  PubMed  Google Scholar 

  • Jenike MA (2004). Obsessive–compulsive disorder. New England Journal of Medicine, 350(3), 259–265

    Google Scholar 

  • Kang DH, Jang JH, Han JY, Jung WH, Choi JS, Choi CH, Kwon JS (2013) Neural correlates of altered response inhibition and dysfunctional connectivity at rest in obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry 40(10):340–346

    PubMed  Google Scholar 

  • Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Morei P, Williamson D, Ryan N (1997) Schedule for affective disorders and schizophrenia for school-Age children – present and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 36(7):980–988

    CAS  PubMed  Google Scholar 

  • Labad J, Menchon JM, Alonso P, Segalàs C, Jimenez S, Vallejo J (2005) Female reproductive cycle and obsessive-compulsive disorder. J Clin Psychiatry 66(4):428–435

    PubMed  Google Scholar 

  • Labad J, Menchon JM, Alonso P, Segalàs C, Jimenez S, Jaurrieta N, Leckman JF, Vallejo J (2008) Gender differences in obsessive-compulsive symptom dimensions. Depress Anxiety 25(10):832–838

    PubMed  Google Scholar 

  • Lensi P, Cassano GB, Correddu G, Ravagli S, Kunovac JL, Akiskal HS (1996) Obsessive-compulsive disorder: familial-developmental history, symptomatology, comorbidity and course with special reference to gender-related differences. Br J Psychiatry 169(1):101–107

    CAS  PubMed  Google Scholar 

  • Lewin AB, Piacentini J (2010) Evidence-based assessment of child obsessive compulsive disorder: recommendations for clinical practice and treatment research. Child Youth Care Forum 39:73–90

    PubMed Central  PubMed  Google Scholar 

  • Lochner C, Hemmings SM, Kinnear CJ, Moolman-Smook JC, Corfield VA, Knowles JA, Niehaus DJ, Stein DJ (2004) Gender in obsessive–compulsive disorder: clinical and genetic findings. Eur Neuropsychopharmacol 14(2):105–113

    CAS  PubMed  Google Scholar 

  • Maina G, Albert U, Bogetto F, Vaschetto P, Ravizza L (1999) Recent life events and obsessive-compulsive disorder (OCD): the role of pregnancy/delivery. Psychiatry Res 89(1):49–58

    CAS  PubMed  Google Scholar 

  • Mataix-Cols D, Rahman Q, Spiller M, Alonso M, Piffarré J, Menchón JM, Vallejo J (2006) Are there sex differences in neuropsychological functions among patients with obsessive-compulsive disorder? Appl Neuropsychol 13(1):42–50

    PubMed  Google Scholar 

  • Mataix‐Cols D, Frost RO, Pertusa A, Clark LA, Saxena S, Leckman JF, Wilhelm S (2010) Hoarding disorder: a new diagnosis for DSM‐V? Depress Anxiety 27(6):556–572

    PubMed  Google Scholar 

  • Menzies L, Chamberlain SR, Laird AR, Thelen SM, Sahakian BJ, Bullmore ET (2008) Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited. Neurosci Biobehav Rev 32(3):525–549

    PubMed Central  PubMed  Google Scholar 

  • Milad MR, Rauch S (2012) Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways. Trends Cogn Sci 16(1):43–51

    PubMed  Google Scholar 

  • Mink JW (2001). Basal ganglia dysfunction in Tourette’s syndrome: a new hypothesis. Pediatric neurology, 25(3), 190–198

    Google Scholar 

  • Misri S, Milis L (2004) Obsessive-compulsive disorder in the postpartum: open-label trial of quetiapine augmentation. J Clin Psychopharmacol 24(6):624–627

    CAS  PubMed  Google Scholar 

  • Miyake A, Friedman NP, Emerson MJ, Witzki AH, Howerter A, Wager TD (2000) The unity and diversity of executive functions and their contributions to complex “frontal lobe” tasks: a latent variable analysis. Cogn Psychol 41:49–100

    CAS  PubMed  Google Scholar 

  • Mundo E, Bareggi SR, Pirola R, Bellodi L (1999) Effect of acute intravenous clomipromine and antiobsessional response to proserotonergic drugs: is gender a predictive variable? Biol Psychiatry 45:290–294

    CAS  PubMed  Google Scholar 

  • Murphy TK, Storch EA, Lewin AB, Edge PJ, Goodman WK (2012) Clinical factors associated with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. J Pediatr 160(2):314–319

    PubMed Central  PubMed  Google Scholar 

  • National Institute for Health and Clinical Excellence (2005) Obsessive-compulsive disorder: core interventions in the treatment of obsessive-compulsive disorder and body dysmorphic disorder. Institute for Health and Clinical Excellence, National

    Google Scholar 

  • Navarro P, García-Esteve L, Ascaso C, Aguado J, Gelabert E, Martín-Santos R (2008) Non-psychotic psychiatric disorders after childbirth: prevalence and comorbidity in a community sample. J Affect Disord 109(1):171–176

    PubMed  Google Scholar 

  • Nelson EC, Hanna GL, Hudziak JJ, Botterton KN, Heath AC, Todd RD (2001) Obsessive-compulsive scale of the child behavior checklist: specificity, sensitivity, and predictive power. Pediatrics 108(1):E14

    CAS  PubMed  Google Scholar 

  • O’Dwyer AM, Marks I (2000) Obsessive-compulsive disorder and delusions revisited. Br J Psychiatry 176(3):281–284

    PubMed  Google Scholar 

  • Olatunji BO, Davis ML, Powers MB, Smits JA (2012) Cognitive-behavioral therapy for obsessive-compulsive disorder: a meta-analysis of treatment outcome and moderators. J Psychiatr Res 47:33–41

    PubMed  Google Scholar 

  • Pauls DL (2008) The genetics of obsessive compulsive disorder: a review of the evidence. Am J Med Genet C Semin Med Genet 148C(2):133–139

    PubMed  Google Scholar 

  • Pauls DL (2010) The genetics of obsessive-compulsive disorder: a review. Dialogues Clin Neurosci 12(2):149–163

    PubMed Central  PubMed  Google Scholar 

  • Pauls DL, Alsobrook JP, Goodman W, Rasmussen S, Leckman JF (1995) A family study of obsessive-compulsive disorder. Am J Psychiatry 152(1):76–84

    CAS  PubMed  Google Scholar 

  • Rachman S, de Silva P (1978) Abnormal and normal obsessions. Behav Res Ther 16(4):233–248

    CAS  PubMed  Google Scholar 

  • Rasmussen SA, Eisen JL (1990) Epidemiology of obsessive compulsive disorder. J Clin Psychiatry 51(2):10–13

    PubMed  Google Scholar 

  • Rasmussen SA, Eisen JL (1992) The epidemiology and clinical features of obsessive-compulsive disorder. Psychiatr Clin North Am 15(4):743–758

    CAS  PubMed  Google Scholar 

  • Ravi Kishore V, Samar R, Janardhan Reddy YC, Chandrasekhar CR, Thennarasu K (2004) Clinical characteristics and treatment response in poor and good insight obsessive-compulsive disorder. Eur Psychiatry 19(4):202–208

    CAS  PubMed  Google Scholar 

  • Richter MA, Summerfeldt LJ, Antony MM, Swinson RP (2003) Obsessive-compulsive spectrum conditions in obsessive-compulsive disorder and other anxiety disorders. Depress Anxiety 18(3):118–127

    PubMed  Google Scholar 

  • Rolls ET (2004) The functions of the orbitofrontal cortex. Brain Cogn 55:11–29

    PubMed  Google Scholar 

  • Ross LE, McLean LM (2006) Anxiety disorders during pregnancy and the postpartum period: a systematic review. J Clini Psychiatry 67(8):1285–1298

    Google Scholar 

  • Rotge J, Guehl D, Dilharreguy B, Tignol J, Bioulac B, Allard M, Burbaud P, Aouizerate B (2009) Meta-analysis of brain volume changes in obsessive-compulsive disorder. Biol Psychiatry 65:75–83

    PubMed  Google Scholar 

  • Ruscio AM, Stein DJ, Chiu WT, Kessler RC (2010) The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication. Mol Psychiatry 15(1):53–63

    PubMed Central  CAS  PubMed  Google Scholar 

  • Russell EJ, Fawcett JM, Mazmanian D (2013) Risk of obsessive-compulsive disorder in pregnant and postpartum women: a meta-analysis. J Clin Psychiatry 74(4):377–385

    CAS  PubMed  Google Scholar 

  • Salkovskis PM, Harrison J (1984) Abnormal and normal obsessions: a replication. Behav Res Ther 22(5):549–552

    CAS  PubMed  Google Scholar 

  • Sánchez-Meca J, Rosa-Alcázar AI, Iniesta-Sepúlveda M, Rosa-Alcázar Á (2014). Differential efficacy of cognitive-behavioral therapy and pharmacological treatments for pediatric obsessive–compulsive disorder: A meta-analysis. Journal of anxiety disorders, 28(1), 31–44

    Google Scholar 

  • Scahill L, Riddle MA, McSwiggin-Hardin M, Ort SI, King RA, Goodman WK, Cicchetti D, Leckman JF (1997) Children’s Yale-Brown obsessive compulsive scale: reliability and validity. J Am Acad Child Adolesc Psychiatry 36(6):844–852

    CAS  PubMed  Google Scholar 

  • Segalàs C, Alonso P, Labad J, Real E, Pertusa A, Jaurrieta N, Jiménez-Murcia S, Menchón JM, Vallejo J (2010) A case-control study of sex differences in strategic processing and episodic memory in obsessive-compulsive disorder. Compr Psychiatry 51:303–311

    PubMed  Google Scholar 

  • Shafran R, Thordarson DS, Rachman S (1996) Thought-action fusion in obsessive compulsive disorder. J Anxiety Disord 10(5):379–391

    Google Scholar 

  • Sichel DA, Cohen LS, Dimmock JA, Rosenbaum JF (1993) Postpartum obsessive compulsive disorder: a case series. J Clin Psychiatry 54(4):156–159

    CAS  PubMed  Google Scholar 

  • Soomro GM, Altman DG, Rajagopal S, Oakley Browne M (2008). Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD). The Cochrane Library.

    Google Scholar 

  • Spitzer R, Kroenke K, Williams J (1999) Validation and utility of a self-report version of PRIME-MD: the PHQ Primary Care Study. JAMA 282:1737–1744

    CAS  PubMed  Google Scholar 

  • Steketee G, Barlow DH (2002) Obsessive-compulsive disorder. In: Barlow DH (ed) Anxiety and its disorders. The Guilford Press, New York, pp 516–676

    Google Scholar 

  • Steketee G, Frost R, Bogart K (1996) The Yale-Brown Obsessive Compulsive Scale: interview versus self-report. Behav Res Ther 34(8):675–684

    CAS  PubMed  Google Scholar 

  • Steketee G, Chambless DL, Tran GQ (2001) Effects of Axis I and II comorbidity on behavior therapy outcome for obsessive-compulsive disorder and agoraphobia. Compr Psychiatry 42(1):76–86

    CAS  PubMed  Google Scholar 

  • Stewart SE, Yen CH, Stack DE, Jenike MA (2006) Outcome predictors for severe obsessive-compulsive patients in intensive residential treatment. J Psychiatr Res 40(6):511–519

    PubMed  Google Scholar 

  • Stewart SE, Yu D, Sharf JM, Neale BM, Fagerness JA et al (2013) Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry 18:1–11

    Google Scholar 

  • Timpano KR, Abramowitz JS, Mahaffey BL, Mitchell MA, Schmidt NB (2011) Efficacy of a prevention program for postpartum obsessive–compulsive symptoms. J Psychiatr Res 45(11):1511–1517

    PubMed  Google Scholar 

  • Tolin DF (2012) Combining pharmacotherapy and psychological treatments for OCD. In: Steketee G (ed) Oxford handbook of obsessive compulsive and spectrum disorders. Oxford University Press, New York, pp 365–375

    Google Scholar 

  • Tolin DF, Witt ST, Stevens MC (2014) Hoarding disorder and obsessive-compulsive disorder show different patterns of neural activity during response inhibition. Psychiatry Res 221:142–148

    PubMed Central  PubMed  Google Scholar 

  • Torresan RC, de Abreu Ramos-Cerqueira AT, de Mathis MA, Diniz JB, Ferrão YA, Miguel EC, Torres AR (2009) Sex differences in the phenotypic expression of obsessive-compulsive disorder: an exploratory study from Brazil. Compr Psychiatry 50(1):63–69

    PubMed  Google Scholar 

  • Torresan RC, Ramos-Cerqueira ATA, Shavitt RG, do Rosário MC, de Mathis MA, Miguel EC, Torres AR (2013) Symptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorder. Psychiatry Res 209:186–195

    PubMed  Google Scholar 

  • Tükel R, Polat A, Genç A, Bozkurt O, Atlı H (2004) Gender-related differences among Turkish patients with obsessive-compulsive disorder. Compr Psychiatry 45(5):362–366

    PubMed  Google Scholar 

  • Watson HJ, Rees CS (2008). Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder. Journal of Child Psychology and Psychiatry, 49(5), 489–498

    Google Scholar 

  • Wilhelm S, Steketee GS (2006) Cognitive therapy for obsessive compulsive disorder: a guide for professionals. New Harbinger Publications, Oakland

    Google Scholar 

  • Wilhelm S, Buhlmann U, Tolin DF, Meunier SA, Pearlson GD, Reese HE, Cannistraro P, Jenike MA, Rauch SL (2008) Augmentation of behavior therapy with d-cycloserine for obsessive compulsive disorder. Am J Psychiatry 165(3):335–341

    PubMed  Google Scholar 

  • Williams MT (2008) Homosexuality anxiety: a misunderstood form of OCD. In: Sebeki LV (ed) Leading-edge health education issues. Nova Science, New York, pp 195–205

    Google Scholar 

  • Williams MT, Farris SG (2011) Sexual orientation obsessions in obsessive-compulsive disorder: prevalence and correlates. Psychiatry Res 187(1):156–159

    PubMed Central  PubMed  Google Scholar 

  • Williams K, Koran L (1997) Obsessive-compulsive disorder in pregnancy, the puerperium, and the premenstrual. J Clin Psychiatry 58:330–334

    CAS  PubMed  Google Scholar 

  • Zambaldi CF, Cantilino A, Montenegro AC, Paes JA, de Albuquerque TLC, Sougey EB (2009) Postpartum obsessive-compulsive disorder: prevalence and clinical characteristics. Compr Psychiatry 50(6):503–509

    PubMed  Google Scholar 

  • Zar M, Wijma K, Wijma B (2002) Relations between anxiety disorders and fear of childbirth during late pregnancy. Clin Psychol Psychother 9(2):122–130

    Google Scholar 

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Hallion, L.S., Sockol, L.E., Wilhelm, S. (2015). Obsessive-Compulsive Disorder. In: Stein, D., Vythilingum, B. (eds) Anxiety Disorders and Gender. Springer, Cham. https://doi.org/10.1007/978-3-319-13060-6_4

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