Abstract
This test is performed to evaluate HPA axis integrity. It is a sensitive alternative test to insulin tolerance test (ITT) in order to evaluate the adrenocorticotrophic hormone (ACTH) reserve.
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References
Fiad TM, Kirby JM, Cunningham SK, McKenna TJ. The overnight single‐dose metyrapone test is a simple and reliable index of the hypothalamic‐pituitary‐adrenal axis. Clin Endocrinol (Oxf). 1994;40(5):603–9.
Steiner H, Bähr V, Exner P, Oelkers P. Pituitary function tests: comparison of ACTH and 11-deoxy-cortisol responses in the metyrapone test and with the insulin hypoglycemia test. Exp Clinic Endocrinol Diabetes. 1994;102(01):33–8.
Gibney J, Healy M, Smith TP, McKenna TJ. A simple and cost-effective approach to assessment of pituitary adrenocorticotropin and growth hormone reserve: Combined use of the overnight metyrapone test and insulin-like growth factor-I standard deviation scores. J Clin Endocrinol Metab. 2008;93(10):3763–8.
Owen LJ, Halsall DJ, Keevil BG. Cortisol measurement in patients receiving metyrapone therapy. Ann Clin Biochem. 2010;47(6):573–5.
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© 2015 Springer International Publishing Switzerland
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Ergin, A., Hamrahian, A., Kennedy, A., Gupta, M. (2015). Metyrapone Stimulation Test. In: The Cleveland Clinic Manual of Dynamic Endocrine Testing. Springer, Cham. https://doi.org/10.1007/978-3-319-13048-4_4
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DOI: https://doi.org/10.1007/978-3-319-13048-4_4
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