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The Pathophysiology of Adenomyosis

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Uterine Adenomyosis

Abstract

Our understanding of adenomyosis remains hampered because of the lack of clarity of the clinical significance of the finding of aberrant endometrial glands and stoma within the myometrium. Despite the growing number of publications and the renewed interest generated by advances in vaginal ultrasounds and magnetic resonance imaging as non-invasive diagnostic techniques, many basic questions remain. Some of the theories of the pathogenesis stem from observations made in early writings with little supporting evidence. More recent research has highlighted a possible role for the myometrium.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Leicester Royal Infirmary, University Hospitals of Leicester, Infirmary Close, Leicester, LE1 5WW, UK

    Marwan Habiba PhD, PhD, FRCOG

  2. Department of Health Sciences, University of Leicester, Leicester, UK

    Marwan Habiba PhD, PhD, FRCOG

  3. Department of Gynaecology, Obstetrics and Urology, Sapienza, University of Rome, Rome, 00161, Italy

    Giuseppe Benagiano MD, PhD, FRCOG

  4. Leuven Centre for Fertility and Embryology, Catholic University of Leuven, Leuven, B-3001, Belgium

    Ivo Brosens MD, PhD, FRCOG

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  1. Marwan Habiba PhD, PhD, FRCOG
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  2. Giuseppe Benagiano MD, PhD, FRCOG
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  3. Ivo Brosens MD, PhD, FRCOG
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Correspondence to Marwan Habiba PhD, PhD, FRCOG .

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  1. Obstetrics and Gynaecology, University Hospitals of Leicester, Leicester, United Kingdom

    Marwan Habiba

  2. Gynaecology, Obstetrics and Urology, Sapienza University, Rome, Italy

    Giuseppe Benagiano

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Habiba, M., Benagiano, G., Brosens, I. (2016). The Pathophysiology of Adenomyosis. In: Habiba, M., Benagiano, G. (eds) Uterine Adenomyosis. Springer, Cham. https://doi.org/10.1007/978-3-319-13012-5_3

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