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Parallel Measurements of in-vivo Skin Autofluorescence Lifetimes and Photobleaching Rates

  • A. Lihachev
  • I. Ferulova
  • J. Spigulis
  • D. Chorvat
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 48)

Abstract

Experimental methodology for parallel measurements of in-vivo skin autofluorescence (AF) lifetimes and photo-bleaching dynamic has been developed and tested. The AF lifetime decay distributions were periodically collected from fixed tissue area with subsequent detection of the fluorescence intensity decrease dynamic at different time shifts after the pulse excitation. Temporal distributions of skin AF lifetimes and bleaching dynamic were collected and analyzed by means of commercial time-correlated single photon counting system. Details of the equipment and data processing are described as well as some measurement results that confirm the feasibility of the proposed technology.

Keywords

in-vivo skin autofluorescence lifetime photo bleaching 

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • A. Lihachev
    • 1
  • I. Ferulova
    • 1
  • J. Spigulis
    • 1
  • D. Chorvat
    • 2
  1. 1.Institute of Atomic Physics and Spectroscopy/ Biophotonics LaboratoryUniversity of LatviaRigaLatvia
  2. 2.International Laser CenterBratislavaSlovakia

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