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Pediatric Hodgkin Lymphoma

  • Georgina W. HallEmail author
  • Cindy L. Schwartz
  • Stephen Daw
  • Louis S. Constine
Chapter
Part of the Hematologic Malignancies book series (HEMATOLOGIC)

Abstract

Pediatric/young adult HL is one of the few childhood malignancies that shares aspects of its biology and natural history with an adult cancer. Historically, children were thought to have a worse prognosis than adults due to antiquated treatment approaches that were initially designed to mitigate toxicities in children. It is now clear that effective therapy provides similar or even superior outcomes in children/young adults. A comparison of the demographics of clinical presentations of pediatric/adolescent HL compared with adult HL is presented in Table 14.1. The first of the bimodal incidence peaks in Hodgkin lymphoma (HL) occurs in teenagers and young adults (15–25-year age group). HL represents less than 5 % of malignancies in children under the age of 15 years. In contrast, it represents 16–20 % of malignancies in adolescents making it the most common malignancy of this age group.

Keywords

Overall Survival Hodgkin Lymphoma Autologous Stem Cell Transplant Brentuximab Vedotin Late Relapse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgment

Thanks to Ann Muhs, Rochester, for her help with the manuscript, particularly the references.

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Copyright information

© Springer International Publishing 2015

Authors and Affiliations

  • Georgina W. Hall
    • 1
    Email author
  • Cindy L. Schwartz
    • 2
  • Stephen Daw
    • 3
  • Louis S. Constine
    • 4
  1. 1.Pediatric and Adolescent Haematology/Oncology UnitChildren’s Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS TrustOxfordUK
  2. 2.Department of Paediatric OncologyMD Anderson Cancer CenterHoustonUSA
  3. 3.Children and Young People’s Cancer Services, Division of PaediatricsUniversity College HospitalLondonUK
  4. 4.Department of Radiation Oncology and Pediatrics, James P. Wilmot Cancer CenterUniversity of Rochester Medical CenterRochesterUSA

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