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Oncological Management of Ependymomas

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Posterior Fossa Tumors in Children

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Abstract

Despite its frequency (third most common brain tumor in children), publications about ependymomas per year are three times less frequent than for medulloblastomas (120 vs. 330). The knowledge and the sophistication of the protocols are lagging behind those of medulloblastomas. Accordingly, this has limited the progress made for these tumors. The improvement of neurosurgery is probably the driving force improving the outcome of children affected with this disease in the last 20 years. The three main questions that remain for ependymomas are the following: (i) Which biomarkers are useful to understand the oncogenesis and prognosis? (ii) Is there a role for chemotherapy? (iii) What is the appropriate strategy at the time of relapse?

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Authors and Affiliations

  1. Pediatric and Adolescent Oncology, Institut Gustave Roussy, Rue Edouard Vaillant, Villejuif, Ile de France, 94805, France

    Jacques Grill M.D., Ph.D. & Maria-Jesus Lobon Iglesias M.D.

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  1. Jacques Grill M.D., Ph.D.
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  2. Maria-Jesus Lobon Iglesias M.D.
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Correspondence to Jacques Grill M.D., Ph.D. .

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Editors and Affiliations

  1. Neurosurgery, Acıbadem University, Istanbul, Istanbul, Turkey

    M. Memet Özek

  2. Pediatric Neurosurgery, Santobono Children's Hospital, Naples, Napoli, Italy

    Giuseppe Cinalli

  3. Dept. Neurosurgery, Royal Childrens Hospital, Melbourne, Victoria, Australia

    Wirginia Maixner

  4. Pediatric Neurosurgery, Hopital Necker-Enfants Malades, Paris, Paris, France

    Christian Sainte-Rose

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Grill, J., Iglesias, MJ.L. (2015). Oncological Management of Ependymomas. In: Özek, M., Cinalli, G., Maixner, W., Sainte-Rose, C. (eds) Posterior Fossa Tumors in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-11274-9_24

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  • DOI: https://doi.org/10.1007/978-3-319-11274-9_24

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-11273-2

  • Online ISBN: 978-3-319-11274-9

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