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Heart and APS

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Book cover Antiphospholipid Antibody Syndrome

Part of the book series: Rare Diseases of the Immune System ((RDIS))

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Abstract

Heart involvement in APS is common, and sometimes, the consequences are significant. Different cardiac structures and apparatuses are involved. Heart valve lesions are the most frequent manifestations; however, the hemodynamic significance is quite uncommon. Coronary arteries and myocardium may also be affected leading to left ventricular dysfunction. Other findings include myocardial microthrombi, secondary pulmonary hypertension, and accelerated atherosclerosis. The treatment of cardiac manifestations in APS is challenging and requires an in-depth knowledge of the disease.

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  1. Department of Cardiologic Thoracic and Vascular Sciences, Padua University Hospital, Via Giustiniani, 2, Padua, 235121, Italy

    Gentian Denas & Vittorio Pengo

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  1. Gentian Denas
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  2. Vittorio Pengo
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  1. Department of Rheumatology, Gaetano Pini Institute, Milan, Milano, Italy

    Pier Luigi Meroni

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Denas, G., Pengo, V. (2015). Heart and APS. In: Meroni, P. (eds) Antiphospholipid Antibody Syndrome. Rare Diseases of the Immune System. Springer, Cham. https://doi.org/10.1007/978-3-319-11044-8_11

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