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Tissue Engineering Breakthroughs

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Bioengineering

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Abstract

Tissue engineering (TE) is an emerging multidisciplinary field involving biology, medicine, and engineering that is likely to revolutionize the ways we improve the health and quality of life for millions of people worldwide by restoring, maintaining, or enhancing tissue and organ function. Three essentials components of TE are: cells, scaffolds and molecules of extracellular matrix, designed to repair tissue defect. In addition to having a therapeutic application, where the tissue is either grown in a patient or outside the patient and transplanted, tissue engineering can have diagnostic applications where the tissue is made in vitro and used for testing drug metabolism and uptake, toxicity, and pathogenicity. The foundation of tissue engineering for either therapeutic or diagnostic applications is the ability to exploit living cells in a variety of ways. Tissue engineering research includes: biomaterials, cells, biomolecules, engineering design aspects, biomechanics, bio-informatics in order to help interventions not only at organ but also at cellular and molecular level. Therefore, gene therapy, manipulations with abzymes and rational vaccine design are also parts of TE. This Chapter will present the crucial breakthroughs in this field.

Stem cell research can revolutionize medicine, more than anything since antibiotics.

Ron Reagan (1911–2004)

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  1. Department of Computer and Electrical Engineering, Florida Atlantic University, Boca Raton, FL, USA

    Mirjana Pavlovic

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  1. Mirjana Pavlovic
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Pavlovic, M. (2015). Tissue Engineering Breakthroughs. In: Bioengineering. Springer, Cham. https://doi.org/10.1007/978-3-319-10798-1_20

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  • DOI: https://doi.org/10.1007/978-3-319-10798-1_20

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