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Prediction of Standard-Dose PET Image by Low-Dose PET and MRI Images

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Machine Learning in Medical Imaging (MLMI 2014)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 8679))

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Positron emission tomography (PET) is a nuclear medical imaging technology that produces 3D images of tissue metabolic activity in human body. PET has been used in various clinical applications, such as diagnosis of tumors and diffuse brain disorders. High quality PET image plays an essential role in diagnosing diseases/disorders and assessing the response to therapy. In practice, in order to obtain the high quality PET images, standard-dose radionuclide (tracer) needs to be used and injected into the living body. As a result, it will inevitably increase the risk of radiation. In this paper, we propose a regression forest (RF) based framework for predicting standard-dose PET images using low-dose PET and corresponding magnetic resonance imaging (MRI) images instead of injecting the standard-dose radionuclide into the body. The proposed approach has been evaluated on a dataset consisting of 7 subjects using leave-one-out cross-validation. Moreover, we compare the prediction performance between sparse representation (SR) based method and our proposed method. Both qualitative and quantitative results illustrate the practicability of our proposed method.

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Kang, J. et al. (2014). Prediction of Standard-Dose PET Image by Low-Dose PET and MRI Images. In: Wu, G., Zhang, D., Zhou, L. (eds) Machine Learning in Medical Imaging. MLMI 2014. Lecture Notes in Computer Science, vol 8679. Springer, Cham.

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-10580-2

  • Online ISBN: 978-3-319-10581-9

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