Abstract
Currently recommended antimalarial agents consist of a variety of agents from different drug classes. Differences in mechanisms of action allow for synergistic combinations and increased therapeutic success. A summary of pharmacological and pharmacokinetic considerations is given in Table 2.1 for chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, quinine/quinidine, artemisinin (the artemisinin agents, artemether, artesunate, and dihydroartemisin, are closely related and summarized as a class, where applicable), lumefantrine, primaquine, atovaquone, and proguanil.
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Kiang, T.K.L., Wilby, K.J., Ensom, M.H.H. (2015). Pharmacology of Recommended Antimalarial Agents. In: Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials. Adis, Cham. https://doi.org/10.1007/978-3-319-10527-7_2
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DOI: https://doi.org/10.1007/978-3-319-10527-7_2
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