Abstract
Malaria is a major tropical health burden worldwide and currently the most important parasitic disease in humans (White et al. 2014). It is prevalent in 108 countries that are inhabited by approximately 3 billion people. The most recent estimates from the World Health Organization (WHO) (WHO 2014a, b) suggest there were approximately 207 million cases of malaria in 2012 and 627,000 deaths related to the disease. Most deaths occurred among children living in Africa. However, since 2000, deaths due to malaria have decreased by 42 % worldwide and rates of malaria-related deaths among children in Africa have decreased by 54 % (WHO 2014a).
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Kiang, T.K.L., Wilby, K.J., Ensom, M.H.H. (2015). Introduction. In: Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials. Adis, Cham. https://doi.org/10.1007/978-3-319-10527-7_1
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DOI: https://doi.org/10.1007/978-3-319-10527-7_1
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