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Introducing Interactive Inverse FEM Simulation and Its Application for Adaptive Radiotherapy

  • Eulalie Coevoet
  • Nick Reynaert
  • Eric Lartigau
  • Luis Schiappacasse
  • Jérémie Dequidt
  • Christian Duriez
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8674)

Abstract

We introduce a new methodology for semi-automatic deformable registration of anatomical structures, using interactive inverse simulations. The method relies on non-linear real-time Finite Element Method (FEM) within a constraint-based framework. Given a set of few registered points provided by the user, a real-time optimization adapts the boundary conditions and(/or) some parameters of the FEM in order to obtain the adequate geometrical deformations. To dramatically fasten the process, the method relies on a projection of the model in the space of the optimization variables. In this reduced space, a quadratic programming problem is formulated and solved very quickly. The method is validated with numerical examples for retrieving Young’s modulus and some pressures on the boundaries. Then, we apply the approach for the registration of the parotid glands during the radiotherapy of the head and neck cancer. Radiotherapy treatment induces weight loss that modifies the shape and the positions of these structures and they eventually intersect the target volume. We show how we could adapt the planning to limit the radiation of these glands.

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Eulalie Coevoet
    • 1
    • 2
  • Nick Reynaert
    • 1
  • Eric Lartigau
    • 1
  • Luis Schiappacasse
    • 1
  • Jérémie Dequidt
    • 2
  • Christian Duriez
    • 2
  1. 1.Oscar Lambret HospitalLilleFrance
  2. 2.INRIAUniversity of Lille 1France

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