Abstract
“Cholesterol is good for your skin” may be an improbable headline that you would see in a health magazine—but it is the reality. Cholesterol is required to form membranes in cells and is also crucial for the formation of the extracellular lamellae in the stratum corneum that provides the permeability barrier for the skin. Keratinocytes in the epidermis, as they stratify and differentiate, synthesize a variety of structural proteins (primarily keratins but also the proteins that form the cornified envelope such as involucrin and loricrin) as well as lipids which are packaged in secretory organelles termed as the epidermal lamellar bodies (LBs).
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Menon, G., Feingold, K. (2015). Chapter 6 Cholesterol Metabolism in the Epidermis. In: Pappas, A. (eds) Lipids and Skin Health. Springer, Cham. https://doi.org/10.1007/978-3-319-09943-9_6
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