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Single-Molecule Fluorescence Spectroscopy of the Folding of a Repeat Protein

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Abstract

Repeat proteins account for more than 5 % of the proteins in multi-cellular organisms. In contrast to globular proteins that have extensive long-range contacts, the structures of repeat proteins show mainly intra- and inter-repeat local contacts. These simple topologies facilitate modeling of the folding mechanism. Tetratricopeptide repeat (TPR) is a 34-amino acid helix-turn-helix motif found in tandem arrays in many natural proteins.

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  1. Chemical Physics Department, Weizmann Institute of Science, Rehovot, Israel

    Sharona Cohen

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  1. Sharona Cohen
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Cohen, S. (2016). Introduction. In: Single-Molecule Fluorescence Spectroscopy of the Folding of a Repeat Protein. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-09558-5_1

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