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Liver Metastases from Stomach Cancer

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Noncolorectal, Nonneuroendocrine Liver Metastases
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Abstract

Gastric carcinoma is a malignant epithelial tumor of the stomach mucosa. Adenocarcinoma of the esophagogastric junction is another clinical entity and is difficult to distinguish from gastric carcinoma. Gastric cancer is estimated to be the fifth most common type of cancer with 952,000 cases worldwide (6.8 % of the total) and is the third leading cause of cancer death (723,000 deaths, 8.8 % of the total) worldwide, according to a report in GLOBOCAN 2012 by the World Health Organization. The incidence of gastric cancer varies with geographic regions, with half of the cases worldwide occurring in Eastern Asia. The highest estimated mortality rates are in Eastern Asia (24 per 100,000 in men, 9.8 per 100,000 in women) and the lowest in Northern America (2.8 and 1.5 per 100,000, respectively) (Fig. 11.1). High mortality rates are also present in both sexes in Central and Eastern Europe and in Central and South America. Age-standardized incidence rates are about twice as high in men as in women, ranging from 3.3 per 100,000 in Western Africa to 35.4 per 100,000 in Eastern Asia for men and from 2.6 per 100,000 in Western Africa to 13.8 per 100,000 in Eastern Asia for women. However, there has been a rapid decline in the incidence of gastric cancer and a steady decline in gastric cancer mortality worldwide. In some Western countries, rates have decreased by more than one third within just one generation. There is about a 20-fold difference in the incidence rates when comparing the rates in Japan with those of some white populations from the USA and of some African countries. The intestinal type of adenocarcinoma is more common in high-risk areas, while the diffuse type is more common in low-risk areas.

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Saiura, A. (2015). Liver Metastases from Stomach Cancer. In: Di Carlo, I. (eds) Noncolorectal, Nonneuroendocrine Liver Metastases. Springer, Cham. https://doi.org/10.1007/978-3-319-09293-5_11

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