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Small Vessel Disease in CKD, Diabetes, Obesity and Hypertension

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Cardio-Renal Clinical Challenges

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Abstract

In the Western world diabetes and hypertension are the most common causes of renal disease and the consequent need for renal replacement therapy. Obesity has emerged as one of the major healthcare challenges afflicting the populations of developed and developing countries alike. In the clinic setting, obesity is seldom seen in isolation; rather it is often encountered together with diabetes mellitus, or impaired glucose homeostasis, and hypertension, a constellation of diseases defined as the metabolic syndrome. The disease entities under the umbrella of the metabolic syndrome each contribute to small vessel changes that ultimately lead to end organ damage including renal failure.

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Authors and Affiliations

  1. Institute of Cardiovascular Sciences, The University of Manchester, Core Technology Facility (3rd floor), 46 Grafton Street, Manchester, M13 9NT, UK

    Reza Aghamohammadzadeh MB, ChB (Honours), MRCP, PhD & Anthony M. Heagerty MBBS, MD, FRCP, FAHA, FMedSci

  2. Southmead hospital, Southmead way, Bristol, Avon, BS10 5NB, UK

    Emma C. Wylie

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  1. Reza Aghamohammadzadeh MB, ChB (Honours), MRCP, PhD
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  2. Emma C. Wylie
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  3. Anthony M. Heagerty MBBS, MD, FRCP, FAHA, FMedSci
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Correspondence to Reza Aghamohammadzadeh MB, ChB (Honours), MRCP, PhD .

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Editors and Affiliations

  1. Renal and Transplantation Department, Guy's Hospital, London, United Kingdom

    David Goldsmith

  2. Gr. T. Popa University of Medicine and Pharmacy, Iasi, Romania

    Adrian Covic

  3. Karolinska Institutet Danderyd University Hospital, Stockholm, Sweden

    Jonas Spaak

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Aghamohammadzadeh, R., Wylie, E.C., Heagerty, A.M. (2015). Small Vessel Disease in CKD, Diabetes, Obesity and Hypertension. In: Goldsmith, D., Covic, A., Spaak, J. (eds) Cardio-Renal Clinical Challenges. Springer, Cham. https://doi.org/10.1007/978-3-319-09162-4_2

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