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Uveitis pp 207–209Cite as

Medication Induced

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Abstract

Medication- or drug-induced uveitis is a relatively rare adverse effect related to drug administration. Many agents have been potentially implicated as instigators of intraocular inflammation. The treatment of choice is cessation of the offending agent and administration of topical and/or systemic corticosteroids depending upon the severity and location of the inflammation. The prognosis is generally favorable as these events tend to be mild to moderate in severity.

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References

  1. Fraunfelder FW, Rosenbaum JT. Drug-induced uveitis. Incidence, prevention and treatment. Drug Saf. 1997;17(3):197–207.

    Article  CAS  PubMed  Google Scholar 

  2. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30:224–39.

    Article  Google Scholar 

  3. Tseng AL, Walmsley SL. Rifabutin-associated uveitis. Ann Pharmacother. 1995;29:1149–55.

    Article  CAS  PubMed  Google Scholar 

  4. Siegal FP, Eilbott D, Burger H, Gehan K, Davidson B, Kaell AT, Weiser B. Dose-limiting toxicity of rifabutin in AIDS-related complex: syndrome of arthralgia/arthritis. AIDS. 1990;4(5):433–41.

    Article  CAS  PubMed  Google Scholar 

  5. Akler ME, Johnson DW, Burman WJ, Johnson SC. Anterior uveitis and hypotony after intravenous cidofovir for the treatment of cytomegalovirus retinitis. Ophthalmology. 1998;105(4):651–7.

    Article  CAS  PubMed  Google Scholar 

  6. Ambati JK, Wynne KB, Angerame MC, Robinson MR. Anterior uveitis associated with intravenous cidofovir use in patients with cytomegalovirus retinitis. Br J Ophthal. 1999;83(10):1153–8.

    Article  CAS  Google Scholar 

  7. Fraunfelder FW, Fraunfelder FT, Jensvold B. Scleritis and other ocular side effects associated with pamidronate disodium. Am J Ophthal. 2003;135(2):219–22.

    Article  CAS  PubMed  Google Scholar 

  8. Fraunfelder FW. Ocular side effects associated with bisphosphonates. Drugs Today (Barc). 2003;39:829–35.

    Article  CAS  Google Scholar 

  9. Durnian JM, Olujohungbe A, Kyle G. Bilateral acute uveitis and conjunctivitis after zoledronic acid therapy. Eye. 2005;19(2):221–2.

    Article  CAS  PubMed  Google Scholar 

  10. Tilden ME, Rosenbaum JT, Fraunfelder FT. Systemic Sulfonamides as a cause of bilateral, anterior uveitis. Arch Ophthal. 1991;109(1):67–9.

    Article  CAS  PubMed  Google Scholar 

  11. Bringas CR, Iglesias CD. Acute and bilateral uveitis secondary to moxifloxacin. Arch Soc Esp Oftalmol. 2004;79(7):357–9.

    Google Scholar 

  12. Wefers BR, Brouwers K, et al. Uveitis-like syndrome and iris transillumination after the use of oral moxifloxacin. Eye (Lond). 2009;23(12):2260–2.

    Article  Google Scholar 

  13. Ramos-Casals M, Diaz-Lagares C, Cuadrado MJ, Khamashta MA. BIOGEAS Study Group. Autoimmune diseases induced by biological agents: a double-edged sword? Autoimmun Rev. 2010;9(3):188–93.

    Article  CAS  PubMed  Google Scholar 

  14. Lim LL, Fraunfelder FW, Rosenbaum JT. Do tumor necrosis factor inhibitors cause uveitis? Registry-Based Study. Arthritis Rheum. 2007;56(10):3248–52.

    Article  CAS  PubMed  Google Scholar 

  15. Jabbarpoor Bonyadi MH, Soheilian R, Soheilian M. Topiramate-induced bilateral anterior uveitis associated with hypopyon formation. Ocular Immunol Inflamm. 2011;19(1):86–8.

    Article  Google Scholar 

  16. Caraco Y, Arnon R, Raveh D. Quinidine-induced uveitis. Isr J Med Sci. 1992;28(10):741–3.

    CAS  PubMed  Google Scholar 

  17. Cano PJ, Diaz-Llopis M. Drug induced uveitis. Archivos de la Sociedad Espanola de Oftalmologia. 2005;80(3):137–49.

    Google Scholar 

  18. Kinshuck D. Glauline (metipranolol) induced uveitis and increase in intraocular pressure. Br J Ophthalmol. 1991;75(9):575.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Taylor HR, Murphy RP, Newland HS, White AT, D’Anna SA, Keyvan-Larijani E, Aziz MA, Cupp EW, Greene BM. Treatment of onchocerciasis. The ocular effects of ivermectin and diethylcarbamazine. Arch Ophthalmol. 1986;104(6):863–70.

    Article  CAS  PubMed  Google Scholar 

  20. Martins JC, Wilensky JT, Asseff CF, Obstbaum SA. Buerk KM Corticosteroid-induced uveitis. Am J Ophthalmol. 1974;77(4):433–7.

    Article  CAS  PubMed  Google Scholar 

  21. Byles DB, Frith P, Salmon JF. Anterior uveitis as a side effect of topical brimonidine. Am J Ophthalmol. 2000;130(3):287–91.

    Article  CAS  PubMed  Google Scholar 

  22. Warwar RE, Bullock JD, Ballal D. Cystoid macular edema and anterior uveitis associated with latanoprost use. Experience and incidence in a retrospective review of 94 patients. Ophthalmology. 1998;105(2):263–8.

    Article  CAS  PubMed  Google Scholar 

  23. Ladas ID, Karagiannis DA, Rouvas AA, Kotsolis AI, Liotsou A, Vergados I. Safety of repeat intravitreal injections of bevacizumab versus ranibizumab: our experience after 2,000 injections. Retina. 2009;29(3):313–8.

    Article  PubMed  Google Scholar 

  24. Wang LC, Yang CM. Sterile endophthalmitis following intravitreal injection of triamcinolone acetonide. Ocul Immunol Inflamm. 2005;13(4):295–300.

    Google Scholar 

  25. Jacob M, Gambrelle J, Fleury J, Durieu I, Kodjikian L, Duquesne N, Grange JD. Panuveitis following intravesical bacille Calmette-Guerin therapy. J Fr Ophtalmol. 2006;29(5):552–5.

    Article  CAS  PubMed  Google Scholar 

  26. Islam SM, El-Sheikh HF, Tabbara KF. Anterior uveitis following combined vaccination for measles, mumps and rubella (MMR): a report of two cases. Acta Ophthalmol Scand. 2000;78(5):590–2.

    Article  CAS  PubMed  Google Scholar 

  27. Blanche P, Decrette C, Sicard D. Development of uveitis following vaccination for influenza. Clin Infect Dis. 1994;19(5):979.

    Article  CAS  PubMed  Google Scholar 

  28. Fraunfelder FW, Suhler EB, Fraunfelder FT. Hepatitis B vaccine and uveitis: an emerging hypothesis suggested by review of 32 case reports. Cutan Ocul Toxicol. 2010;29(1):26–9.

    Article  PubMed  Google Scholar 

  29. Papavasileiou E, Prasad S, Freitag SK, Sobrin L, Lobo AM. Ipilimumab-induced ocular and orbital inflammation-a case series and review of the literature. Ocul Immunol Inflamm. 2015;24:1–7.

    Article  Google Scholar 

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Correspondence to George N. Papaliodis .

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Papaliodis, G.N. (2017). Medication Induced. In: Papaliodis, G. (eds) Uveitis. Springer, Cham. https://doi.org/10.1007/978-3-319-09126-6_28

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  • DOI: https://doi.org/10.1007/978-3-319-09126-6_28

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-09125-9

  • Online ISBN: 978-3-319-09126-6

  • eBook Packages: MedicineMedicine (R0)

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