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Obesity and Osteoporosis

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Book cover Multidisciplinary Approach to Obesity

Abstract

The belief that obesity is protective against osteoporosis has recently been revised. In fact latest epidemiologic and clinical studies show that a high level of fat mass, but also reduced muscle mass, might be a risk factor for osteoporosis and fragility fractures. Further, increasing evidence seems to indicate that different components such as myokines, adipokines, and growth factors, released by both fat and muscle tissues, could play a key role in the regulation of skeletal health and in low bone mineral density and, thus, in osteoporosis development. This chapter considers old and recent data in the literature to further evaluate the relationship between fat and bone tissue.

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Author information

Authors and Affiliations

  1. Department of Experimental Medicine, Section of Medical Pathophysiology, Endocrinology and Nutrition, Sapienza University, Rome, Italy

    Emanuela A. Greco, Lorenzo M. Donini & Andrea Lenzi

  2. Department of Movement, Human and Health Sciences, Unit of Endocrinology, Foro Italico University, Largo Lauro De Bosis 15, 00135, Rome, Italy

    Silvia Migliaccio MD, PhD

Authors
  1. Emanuela A. Greco
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  2. Lorenzo M. Donini
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  3. Andrea Lenzi
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  4. Silvia Migliaccio MD, PhD
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Corresponding author

Correspondence to Silvia Migliaccio MD, PhD .

Editor information

Editors and Affiliations

  1. Department of Experimental Medicine, Section of Medical Pathophysiology, Endocrinology and Nutrition, Sapienza University, Rome, Italy

    Andrea Lenzi

  2. Department of Movement, Human and Health Sciences, Unit of Endocrinology, Foro Italico University, Rome, Italy

    Silvia Migliaccio

  3. Department of Experimental Medicine, Section of Medical Pathophysiology, Endocrinology and Nutrition, Sapienza University, Rome, Italy

    Lorenzo Maria Donini

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© 2015 Springer International Publishing Switzerland

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Greco, E.A., Donini, L.M., Lenzi, A., Migliaccio, S. (2015). Obesity and Osteoporosis. In: Lenzi, A., Migliaccio, S., Donini, L. (eds) Multidisciplinary Approach to Obesity. Springer, Cham. https://doi.org/10.1007/978-3-319-09045-0_8

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  • DOI: https://doi.org/10.1007/978-3-319-09045-0_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-09044-3

  • Online ISBN: 978-3-319-09045-0

  • eBook Packages: MedicineMedicine (R0)

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