Abstract
Pharmaceutical Nanotechnology can provide challenges for producing innovative drugs based on bio-inspired nanostructures (advanced Drug Delivery nano Systems—aDDnSs) [1]. These systems could be correlated to the living organisms due to their self-assembly properties, their hierarchical structural organization, as well as to their biocompatibility and biodegradability characteristics. aDDnSs can be considered as new therapeutic outcomes in nanomedicine that may be able to deliver pharmacomolecules to specific tissues and can improve their PK/PD (pharmacokinetics/pharmacodynamics) behavior and affect their total bioavailability. Drug delivery is a scientific sector that promotes the innovation by designing formulation approaches that can produce aDDnSs. Drug nanocarriers produced by the combination of bionanomaterials, such as liposomes, (co)polymers and dendrimers, are considered as new classes of complex self-assembled soft nanostructures.
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References
Demetzos C, Pippa N (2014) Advanced drug delivery nano systems (aDDnSs): a mini-review. Drug Deliv 21(4):250–257
Pippa N, Kaditi E, Pispas S, Demetzos C (2013) PEO-b-PCL/DPPC chimeric nanocarriers: self-assembly aspects in aqueous and biological media and drug incorporation. Soft Matter 9:4073
Pippa N, Merkouraki M, Pispas S, Demetzos C (2013) DPPC:MPOx chimeric advanced Drug Delivery nanosystems (chi-aDDnSs): physicochemical and structural characterization, stability and drug release studies. Int J Pharm 450(1–2):1
Pippa N, Kaditi E, Pispas S, Demetzos C (2013) DPPC/poly(2-methyl-2-oxazoline)-grad-poly(2-phenyl-2-oxazoline) chimeric nanostructures as potential drug nanocarriers. J Nanopart Res 15:1685
Pippa N, Psarommati F, Pispas S, Demetzos C (2013) The shape/morphology balance: a study of stealth liposomes via fractal analysis and drug encapsulation. Pharm Res 30(9):2385
Pippa N, Dokoumetzidis A, Demetzos C, Macheras P (2013) On the ubiquitous presence of fractals and fractal concepts in pharmaceutical sciences: a review. Int J Pharm 456:340
Pippa N, Gardikis K, Pispas S, Demetzos C (2014) The physicochemical/thermodynamic balance of advanced drug liposomal delivery systems. J Therm Anal Calorim 116(1):99–105
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Pippa, N., Pispas, S., Demetzos, C. (2015). Bio-inspired Chimeric Drug Delivery nano Systems (Chi-DDnSs): Their Fractal Hologram and Regulatory Aspects. In: Vlamos, P., Alexiou, A. (eds) GeNeDis 2014. Advances in Experimental Medicine and Biology, vol 822. Springer, Cham. https://doi.org/10.1007/978-3-319-08927-0_23
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DOI: https://doi.org/10.1007/978-3-319-08927-0_23
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