Abstract
This chapter deals with the classification of Drug Delivery nano Systems (DDnSs) with a Modulatory Controlled Release profile (MCR) denoted as Modulatory Controlled Release nano Systems (MCRnSs). Conventional (c) and advanced (a) DDnSs are denoted by the acronyms cDDnSs and aDDnSs, and can be composed of a single or more than one biomaterials, respectively. The classification was based on their characteristics such as surface functionality (f), the nature of biomaterials used, and the kind of interactions between biomaterials. The aDDnSs can be classified as Hybridic (Hy-) or Chimeric (Chi-) based on the nature—same or different, respectively—of biomaterials and inorganic materials used. The nature of the elements used for producing advanced biomaterials is of great importance and medicinal chemistry contributes effectively to the production of aDDnSs.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gaspar R, Aksu B, Cuine A, Danhof M, Takac MJ, Linden HH, Link A, Muchitsch EM, Rowland M, Noe CR, Smith DA, Tucker GT, Crommelin DJ, Peck CC, Rocci ML Jr, Basançon L, Shah VP (2012) Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years. J Pharm Sci 101:4075
Gardikis K, Hatziantoniou S, Bucos M, Fessas D, Signorelli M, Felekis T, Zervou M, Screttas C, Steele B, Ionov M, Scretta M, Klajnert B, Bryszewska M, Demetzos C (2010) New drug delivery nanosystem combining liposomal and dendrimeric technology (liposomal locked-in dendrimers) for cancer therapy. J Pharm Sci 99:3561
Pippa N, Pispas S, Demetzos C (2012) The fractal hologram and elucidation of the structure of liposomal carriers in aqueous and biological media. Int J Pharm 430:65
Pippa N, Pispas S, Demetzos C (2012) The delineation of the morphology of charged liposomal vectors via a fractal analysis in aqueous and biological media: physicochemical and self-assembly studies. Int J Pharm 437:264
Pippa N, Kaditi E, Pispas S, Demetzos C (2013) PEO-b-PCL:DPPC chimeric nanocarriers: self-assembly aspects in aqueous and biological media and drug incorporation. Soft Matter 9:4073
Pippa N, Merkouraki M, Pispas S, Demetzos C (2013) DPPC:MPOx chimeric advanced Drug Delivery nano Systems (chi-aDDnSs): physicochemical and structural characterization, stability and drug release studies. Int J Pharm 450:1
Demetzos C, Pippa N (2014) Advanced drug delivery nano systems (aDDnSs): a mini-review. Drug Deliv 21(4):250–257
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Demetzos, C. (2015). Advanced Drug Delivery Nanosystems: Perspectives and Regulatory Issues. In: Vlamos, P., Alexiou, A. (eds) GeNeDis 2014. Advances in Experimental Medicine and Biology, vol 822. Springer, Cham. https://doi.org/10.1007/978-3-319-08927-0_22
Download citation
DOI: https://doi.org/10.1007/978-3-319-08927-0_22
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-08926-3
Online ISBN: 978-3-319-08927-0
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)