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Solitary Rectal Ulcer Syndrome

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Colitis

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Abstract

Solitary rectal ulcer syndrome is a benign condition of the rectum caused by mucosal prolapse. Common clinical symptoms are constipation and red blood loss per anum. The endoscopy can show a variable picture of erythema, a shallow ulcer, or even polypoid lesions. The histology is characteristic. The rectal mucosa shows crypt distortion, reactive epithelial cells, and typical fibromuscular obliteration of the lamina propria. Inflammation is usually mild. This lesion should not be misdiagnosed as neoplasia.

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References

  1. Abid S, Khawaja A, Bhimani SA, Ahmad Z, Hamid S, Jafri W. The clinical, endoscopic and histological spectrum of the solitary rectal ulcer syndrome: a single-center experience of 116 cases. BMC Gastroenterol. 2012;12:72.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Ertem D, Acar Y, Karaa EK, Pehlivanoglu E. A rare and often unrecognized cause of hematochezia and tenesmus in childhood: solitary rectal ulcer syndrome. Pediatrics. 2002;110(6):e79.

    Article  PubMed  Google Scholar 

  3. Sharara AI, Azar C, Amr SS, Haddad M, Eloubeidi MA. Solitary rectal ulcer syndrome: endoscopic spectrum and review of the literature. Gastrointest Endosc. 2005;62:755–62.

    Article  PubMed  Google Scholar 

  4. Li SC, Hamilton SR. Malignant tumors in the rectum simulating solitary rectal ulcer syndrome in endoscopic biopsy specimens. Am J Surg Pathol. 1998;22:106–12.

    Article  CAS  PubMed  Google Scholar 

  5. Ball CG, Dupre MP, Falck V, Hui S, Kirkpatrick AW, Gao ZH. Sessile serrated polyp mimicry in patients with solitary rectal ulcer syndrome: is there evidence of preneoplastic change? Arch Pathol Lab Med. 2005;129:1037–40.

    PubMed  Google Scholar 

  6. Dehgani SM, Haghighat M, Imanieh MH, Geramizadeh B. Solitary rectal ulcer syndrome in children: a prospective study of cases from Southern Iran. Eur J Gastroenterol Hepatol. 2008;20:93–5.

    Article  Google Scholar 

  7. Al-Brahim N, Al-Awadhi N, Al-Enezi S, Alsurayei S, Ahmad M. Solitary rectal ulcer syndrome: a clinicopathological study of 13 cases. Saudi J Gastroenterol. 2009;15:188–92.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Torres C, Khaikin M, Bracho J, Luo CH, Weiss EG, Sands DR, et al. Solitary rectal ulcer syndrome: clinical findings, surgical treatment, and outcomes. Int J Colorectal Dis. 2007;22:1389–93.

    Article  PubMed  Google Scholar 

  9. Madigan MR, Morson BC. Solitary ulcer of the rectum. Gut. 1969;10:871–81.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Tendler DA, Aboudola S, Zacks JF, O’Brien MJ, Kelly CP. Prolapsing mucosal polyps: an underrecognized form of colonic polyp. A clinicopathological study of 15 cases. Am J Gastroenterol. 2002;97:370–6.

    CAS  PubMed  Google Scholar 

  11. Warren BF, Dankwa EK, Davies JD. “Diamond-shaped” crypts and mucosal elastin: helpful diagnostic features in biopsies of rectal prolapsed. Histopathology. 1990;17:129–34.

    Article  CAS  PubMed  Google Scholar 

  12. Londsdale RN. Microvascular abnormalities in the mucosal prolapsed syndrome. Gut. 1993;34:106–9.

    Article  Google Scholar 

  13. Campbell AP, Cobb CA, Chapman RW, Kettlewel M, Hoang P, Haot BJ, Jewell DP. Cap polyposis: an unusual cause of diarrhoea. Gut. 1993;34:562–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Pathology, University of Cagliari, Cagliari, Italy

    Rossano Ambu MD

  2. Department of Pathology, KULeuven, Gasthuisberg, Leuven, Belgium

    Karel Geboes MD, PhD, AGAF

  3. Department of Pathology, UGhent, Gent, Belgium

    Karel Geboes MD, PhD, AGAF

Authors
  1. Rossano Ambu MD
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  2. Karel Geboes MD, PhD, AGAF
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Corresponding author

Correspondence to Rossano Ambu MD .

Editor information

Editors and Affiliations

  1. Department of pathology, KULeuven, Leuven, Belgium

    Karel Geboes

  2. Department of Pathology, University of Cagliari, Cagliari, Italy

    Sonia Nemolato

  3. Department of Pathology, University of Cagliari, Cagliari, Italy

    Maria Leo

  4. Department of Pathology, University of Cagliari, Cagliari, Italy

    Gavino Faa

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© 2014 Springer International Publishing Switzerland

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Ambu, R., Geboes, K. (2014). Solitary Rectal Ulcer Syndrome. In: Geboes, K., Nemolato, S., Leo, M., Faa, G. (eds) Colitis. Springer, Cham. https://doi.org/10.1007/978-3-319-08028-4_13

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  • DOI: https://doi.org/10.1007/978-3-319-08028-4_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-08027-7

  • Online ISBN: 978-3-319-08028-4

  • eBook Packages: MedicineMedicine (R0)

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